Hemispherx’s Alferon And Ampligen Effective Against Ebola Virus

http://www.bidnessetc.com/28451-hemispherxs-alferon-and-ampligen-effective-against-ebola-virus/

Ampligen inhibits human herpesvirus-6 in vitro.

http://www.ncbi.nlm.nih.gov/pubmed/7893986

 

 

New HHV-6 Research Suggests Additional Ampligen(R) Role in Treating CFS 

 http://www.prnewswire.com/news-releases/new-hhv-6-research-suggests-additional-ampligenr-role-in-treating-cfs-77022237.html

  NEW YORK, Oct. 16 /PRNewswire/ -- Hemispherx Biopharma, Inc. (Amex:   HEB)
 said today that recently reported research that indicates Human Herpes Virus 6
 (HHV-6) has a role in pathogenesis of Chronic Fatigue Syndrome (CFS) symptoms
 may further explain Ampligen's(R) potential role in treatment of the disorder.
     Earlier peer-reviewed studies from independent researchers associated with
 the National Institutes of Health (NIH), have shown that Ampligen can
 eradicate HHV-6 infection in vitro; Ampligen demonstrated the maximum
 antiviral activity from a large panel of approximately three dozen prospective
 antiviral/immunological drugs.
     The new HHV-6 research was presented in a paper this past week by
 Dr. D.V. Ablashi of Advanced Biotechnologies Inc. and Georgetown University
 School of Medicine, et. al., at the American Association for Chronic Fatigue
 Conference held in Cambridge, Massachusetts.  Dr. Ablashi, who is a Board
 member of the national association, utilized specialized techniques to
 actually harvest live, replicating virus from a group of CFS patients.
     Dr. Ablashi's scientific abstract, entitled, "Increased Activation of
 Human Herpes Virus-6 (HHV-6) but not Human Herpes Virus-7 (HHV-7) or Human
 Herpes Virus-8 (HHV-8) in Chronic Fatigue Syndrome Patients" detected the
 active replicating HHV-6 in 57% of CFS patients versus only 8% of a normal
 healthy population.
     Hemispherx said that this new finding represents the second disease marker
 to be recently announced, and provides additional evidence for a possible
 Ampligen mechanism in treatment of CFS.  As recently announced, the pioneering
 efforts of Dr. Robert Suhadolnik (U.S.), and subsequent researchers at
 Montpelier University (France) and the Free University of Brussels (Belgium)
 confirmed the identification of a specifically abnormal immune/antiviral
 factor, a natural disease barrier against many viruses, in the blood's immune
 cells from approximately 90% of CFS patients (now termed the "REDD"
 abnormality).
     Hemispherx said that while the proximate cause of CFS remains unknown,
 measuring of both HHV-6 replication and REDD may serve as powerful markers to
 evaluate the disease process itself.  In this case, the active drug would
 function as a type of bifurcated warhead -- attacking both the replicating
 virus (HHV-6) as well as the REDD abnormality which led to the breakdown in
 host defense barriers.
     According to the National Institutes of Health, during the early years of
 life, HHV-6 infection is observed in 90% of the U.S. population, but
 antibodies and the intact immune system thereafter keep the virus in check and
 present only in dormant form.  However, the dysfunctional immune system of
 many CFS sufferers thereafter allows the virus to awake from dormancy and
 renew its replication and growth.
     Currently, Ampligen is the only drug being developed worldwide for
 treatment of CFS at the Phase III clinical trial level.
 
     Information contained in this news release other than historical
 information, should be considered forward-looking and is subject to various
 risk factors and uncertainties.  For instance, the strategies and operations
 of Hemispherx involve risks of competition, changing market conditions,
 changes in laws and regulations affecting these industries and numerous other
 factors discussed in this release and in the Company's filings with the
 Securities and Exchange Commission.  Accordingly, actual results may differ
 materially from those in any forward-looking statements.
 
 

SOURCE  Hemispherx Biopharma, Inc.
 
 cartoon, ampligen, ebola, treatment, cdc,nih, fauci

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