HHV-6 + Zika Virus = lymphoblastic leukemia and myeloid leukemia???
Since Zika virus is a flavivirus, it is likely that both innate and
adaptive responses are required to halt Zika viral replication and clear
the virus, so medical conditions or interventions that influence innate
and/or adaptive immune responses could alter the course of clinical
illness, including the symptoms, severity and duration of infection.
Case reports describing Zika virus infection in patients with conditions associated with compromised immune systems are limited. In Colombia, an adult and a child with confirmed Zika virus infection had severe illness with fatal outcomes. Post mortem examinations suggested probable lymphoblastic leukaemia and myeloid leukaemia, respectively. The role of Zika virus infection in these fatal outcomes is unclear.
Based on experience with acute RNA virus infections in general, immunocompromised patients could have atypical presentations, including absence of fever.
https://www.gov.uk/guidance/zika-virus-and-immunocompromised-patients
Case reports describing Zika virus infection in patients with conditions associated with compromised immune systems are limited. In Colombia, an adult and a child with confirmed Zika virus infection had severe illness with fatal outcomes. Post mortem examinations suggested probable lymphoblastic leukaemia and myeloid leukaemia, respectively. The role of Zika virus infection in these fatal outcomes is unclear.
Based on experience with acute RNA virus infections in general, immunocompromised patients could have atypical presentations, including absence of fever.
https://www.gov.uk/guidance/zika-virus-and-immunocompromised-patients