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Saturday, May 16, 2020

Do the many coinfections in COVID-19 hint at the connection to China's African Swine Fever epidemic?

"In animals with chronic African swine fever, the carcass may be emaciated. Other possible post–mortem lesions include focal areas of skin necrosis, skin ulcers, consolidated lobules in the lung, caseous pneumonia, nonseptic fibrinous pericarditis, pleural adhesions, generalized lymphadenopathy and swollen joints. Some of these lesions may result from secondary infections."
Source:
http://www.cfsph.iastate.edu/Factsheets/pdfs/african_swine_fever.pdf

COVID-19 Study:  In total, 24 respiratory pathogens were found among the patients, and 242 (94.2 %) patients were co-infected with one or more pathogens. 



Abstract:

Accumulating evidence shows that microbial co-infection increases the risk of disease severity in humans. There have been few studies about SARS-CoV-2 co-infection with other pathogens. In this retrospective study, 257 laboratory-confirmed COVID-19 patients in Jiangsu Province were enrolled from January 22 to February 2, 2020. They were re-confirmed by real-time RT-PCR and tested for 39 respiratory pathogens. In total, 24 respiratory pathogens were found among the patients, and 242 (94.2 %) patients were co-infected with one or more pathogens. Bacterial co-infections were dominant in all COVID-19 patients, Streptococcus pneumoniae was the most common, followed by Klebsiella pneumoniae and Haemophilus influenzae. The highest and lowest rates of co-infections were found in patients aged 15–44 and below 15, respectively. Most co-infections occurred within 1–4 days of onset of COVID-19 disease. In addition, the proportion of viral co-infections, fungal co-infections and bacterial-fungal co-infections were the highest severe COVID-19 cases. These results will provide a helpful reference for diagnosis and clinical treatment of COVID-19 patients.
Source:
https://www.sciencedirect.com/science/article/pii/S0168170220303531













COVID-19 Study: In total, 24 respiratory pathogens were found among the patients, and 242 (94.2 %) patients were co-infected with one or more pathogens.

Abstract:

Accumulating evidence shows that microbial co-infection increases the risk of disease severity in humans. There have been few studies about SARS-CoV-2 co-infection with other pathogens. In this retrospective study, 257 laboratory-confirmed COVID-19 patients in Jiangsu Province were enrolled from January 22 to February 2, 2020. They were re-confirmed by real-time RT-PCR and tested for 39 respiratory pathogens. In total, 24 respiratory pathogens were found among the patients, and 242 (94.2 %) patients were co-infected with one or more pathogens. Bacterial co-infections were dominant in all COVID-19 patients, Streptococcus pneumoniae was the most common, followed by Klebsiella pneumoniae and Haemophilus influenzae. The highest and lowest rates of co-infections were found in patients aged 15–44 and below 15, respectively. Most co-infections occurred within 1–4 days of onset of COVID-19 disease. In addition, the proportion of viral co-infections, fungal co-infections and bacterial-fungal co-infections were the highest severe COVID-19 cases. These results will provide a helpful reference for diagnosis and clinical treatment of COVID-19 patients.
Source:
https://www.sciencedirect.com/science/article/pii/S0168170220303531














Nobody should be surprised that COVID-19 is a multisystemic inflammatory syndrome. It is in pigs all over China.







COVID-19 looks more and more like Chronic African Swine Fever


'Weird as hell’: the Covid-19 patients who have symptoms for months

https://www.theguardian.com/world/2020/may/15/weird-hell-professor-advent-calendar-covid-19-symptoms-paul-garner






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