Breaking News: ASF could become a human health risk
"The African swine fever (ASF) virus, may in the
future become dangerous for humans, according to the head of the Russian
Epidemiology Service, Chief State Sanitary Doctor Gennady Onishchenko,
at the press-conference in St. Petersburg. According to him almost all
viruses from time to time go through mutation processes which can give
them some additional functions."
http://www.pigprogress.net/Health-Diseases/Outbreaks/2013/7/ASF-could-become-a-human-health-risk-1308047W/
If HHV-6 is the real cause of AIDS, here are some of the implications:
1. HIV is a massive scientific fraud. Something akin to a Ponzi scheme. Scientists who challenged the HIV theory of AIDS (the ones who have been thuggishly censored and silenced) turn out to be on the money.
2. Chronic Fatigue Syndrome and Autism (and many other so-called HHV-6 related mysterious epidemics) are part of the so-called AIDS epidemic. Chronic Fatigue Syndrome and Autism both are clearly the results of the ravages of HHV-6.
3. AIDS and Chronic Fatigue Syndrome has been artificially and politically separated into two epidemics. We are living in a period of CFS/AIDS apartheid. So-called AIDS patients have to sit in the back of the HHV-6 epidemic bus while the befuddled HHV-6/CFS patients and HHV-6/Autism victims sit up front. Nobody is well-served.
4. AIDS is not a sexually transmitted disease. That paradigm has set a scapegoating and antigay agenda in place that the public thinks is solidly based on science. It is only based on homophobic and racist nosology, epidemiology and virology. The scientists behind the paradigm are charlatans and crooks.
5. The Centers for Disease Control in Atlanta and the Pasteur Institute in Paris have a great deal in common with the institutions of Nazi medicine. For Blacks, everything these institutions have done in the name of AIDS really constitutes a second Tuskegee Syphilis Experiment.
Elements of a Scientific Ponzi Scheme like the Montagnier-Agut HIV Fraud Ponzi Scheme and HHV-6 Cover-up
http://www.pigprogress.net/Health-Diseases/Outbreaks/2013/7/ASF-could-become-a-human-health-risk-1308047W/
Background on African Swine Fever Virus as a human pathogen:
"African Swine fever is an endemic disease in sub-Saharan Africa and
many other parts of the developing world. It is caused by the African
Swine virus that primarily replicates in macrophages and monocytes
leading to the impairment of the structure and function of the immune
system of the infected organisms. Until now the African Swine epidemic
continues to spread despite all efforts to contain it. Thus, there is
an objective need for effective, safe and affordable preventive and
therapeutic approaches, in particular for effective vaccines, to
control and eventually eradicate this disease. Since the characteristic
feature of the African Swine virus is to impair the immune system and
to cause immune deficiencies in its hosts the development of vaccines
and other therapeutic approaches against the African Swine virus has
implications for other immune deficiencies or diseases. Several other
viruses are also known to cause immunodeficiency-like syndromes in
humans, including cytomegalovirus, Epstein Barr Virus
and others. Moreover, a series of cases of so-called "idiopathic"
immunodeficiencies have been documented that display
CD4+T-lymphocytopenia with opportunistic infections, but show no
evidence of HIV infection. Since antibodies for the African Swine virus
have been detected in humans, the possibility of human infection with
the African Swine virus exists and may thus far have escaped any systematic screening. Thus, any preventive and therapeutic approach to African Swine fever can have far-reaching implications to control immune deficiency conditions in humans."http://www.faqs.org/patents/app/20080207875
Detection of Novel Sequences Related to African Swine Fever Virus in Human Serum and Sewage.
Loh J, Zhao G, Presti RM, Holtz LR, Finkbeiner SR, Droit L, Villasana Z, Todd C, Pipas JM, Calgua B, Girones R, Wang D, Virgin HW.
Departments of Pathology & Immunology and Molecular Microbiology, Department of Medicine and Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri; Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Microbiology, Faculty of Biology, University of Barcelona, Barcelona, Spain.
"The family Asfarviridae contains only a single virus species, African swine fever virus (ASFV). ASFV is a viral agent with significant economic impact due to its devastating effects on populations of domesticated pigs during outbreaks, but has not been reported to infect humans. We report here the discovery of novel viral sequences in human serum and sewage which are clearly related to the Asfarvirus family, but highly divergent from ASFV. Detection of these sequences suggests that greater genetic diversity may exist among Asfarviruses than previously thought, and raises the possibility that human infection by Asfarviruses may occur."
Detection of Novel Sequences Related to African Swine Fever Virus in Human Serum and Sewage.
Loh J, Zhao G, Presti RM, Holtz LR, Finkbeiner SR, Droit L, Villasana Z, Todd C, Pipas JM, Calgua B, Girones R, Wang D, Virgin HW.
Departments of Pathology & Immunology and Molecular Microbiology, Department of Medicine and Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri; Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Microbiology, Faculty of Biology, University of Barcelona, Barcelona, Spain.
"The family Asfarviridae contains only a single virus species, African swine fever virus (ASFV). ASFV is a viral agent with significant economic impact due to its devastating effects on populations of domesticated pigs during outbreaks, but has not been reported to infect humans. We report here the discovery of novel viral sequences in human serum and sewage which are clearly related to the Asfarvirus family, but highly divergent from ASFV. Detection of these sequences suggests that greater genetic diversity may exist among Asfarviruses than previously thought, and raises the possibility that human infection by Asfarviruses may occur."
http://www.ncbi.nlm.nih.gov/pubmed/19812170?dopt=Abstract
Cytokines produced by cells of the immune system, including macrophages,
can influence inflammatory responses to viral infection. This has been
exploited by viruses, which have developed strategies to direct the
immune response towards ineffective responses. African swine fever virus
(ASFV) is a double-stranded DNA virus that infects macrophages of
domestic swine. In this study, primary cells of monocyte macrophage
lineage were obtained from the lungs, peritoneum or blood of domestic
swine and, after infection with ASFV, supernatants were tested for
cytokines using biological assays. The cytokine transforming growth
factor-beta (TGF-beta) was detected after infection of macrophage
preparations, but tumour necrosis factor (TNF) and interleukin-1 (IL-1)
were not detected. ASFV-infected and uninfected macrophage populations
were also tested to assess their ability to respond to cytokines by
enhancing production of superoxide in the respiratory burst mechanism.
Responses to interferon-gamma (IFN-gamma) and lipopolysaccharide (LPS)
were suppressed in macrophage populations infected with virus, even at
low multiplicities of infection. Addition of TGF-beta to uninfected
macrophages resulted in a similar suppression of response, but antibody
to TGF-beta did not prevent suppression induced by virus. These results
are discussed in relation to the pathology of African swine fever.
Source:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1364015/
"The natural killing of the human myeloid leukaemia cell line by pig
mononuclear cells was investigated in an 18 hr assay; the most active
natural-killer (NK) effectors were those cells not adhering to
nylon-wool columns or rosetting with sheep red blood cells. Mononuclear
cells cultured in the presence of African swine-fever virus maintained
NK activity. Pigs infected with African swine-fever virus exhibited a
suppressed NK activity, possibly due to the sensitivity of NK cells to
increased temperatures. The possible role of NK cells in recovery from
African swine fever is discussed."
Source:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1454312/
Spin Magazine on John Beldekas
--By JON NORDHEIMER, SPECIAL TO THE NEW YORK TIMES
African Swine Fever Virus (Asfarviridae) sequences found in people with febrile illnesses
Abstract
Virus Identification in Unknown Tropical Febrile Illness Cases Using Deep Sequencing
Dengue virus is an emerging infectious agent that infects an estimated
50–100 million people annually worldwide, yet current diagnostic
practices cannot detect an etiologic pathogen in ∼40% of dengue-like
illnesses. Metagenomic approaches to pathogen detection, such as viral
microarrays and deep sequencing, are promising tools to address
emerging and non-diagnosable disease challenges. In this study, we
used the Virochip microarray and deep sequencing to characterize the
spectrum of viruses present in human sera from 123 Nicaraguan patients
presenting with dengue-like symptoms but testing negative for dengue
virus. We utilized a barcoding strategy to simultaneously deep
sequence multiple serum specimens, generating on average over 1
million reads per sample. We then implemented a stepwise bioinformatic
filtering pipeline to remove the majority of human and low-quality
sequences to improve the speed and accuracy of subsequent unbiased
database searches. By deep sequencing, we were able to detect virus
sequence in 37% (45/123) of previously negative cases. These included
13 cases with Human Herpesvirus 6 sequences. Other samples contained
sequences with similarity to sequences from viruses in the Herpesviridae, Flaviviridae, Circoviridae, Anelloviridae, Asfarviridae, and Parvoviridae
families. In some cases, the putative viral sequences were virtually
identical to known viruses, and in others they diverged, suggesting
that they may derive from novel viruses. These results demonstrate the
utility of unbiased metagenomic approaches in the detection of known
and divergent viruses in the study of tropical febrile illness.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3274504/
" . .. further study is needed to characterize their potential risks to both public health and agricultural development."
http://link.springer.com/article/10.1007%2Fs11262-013-0878-2
http://vir.sgmjournals.org/content/34/3/455.short
Detection of African swine fever virus-like sequences in ponds in the Mississippi Delta through metagenomic sequencing
http://link.springer.com/article/10.1007%2Fs11262-013-0878-2
ASF virus, adapted to grow in VERO cells, produces a strong cytopathic effect in human macrophages leading to cell destruction.
Could this happen to macrophages in humans infected with African Swine Fever Virus?
Source:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1364015/
Will African Swine Fever affect the natural killer cells in humans infected with it?
Source:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1454312/
How to Test for African Swine Fever Virus
Laboratory Diagnosis
Because ASF can easily be confused with other important diseases of
swine, obtaining samples for laboratory diagnosis is an important step
in confirming the illness.
Samples of the following should be sent to the laboratory (they should
be kept as cold as possible, without freezing, during transport):
- Blood in anticoagulant (heparin or ethylenediaminetetraacetic acid [EDTA])
- Spleen
- Tonsil
- Kidney
- Lymph nodes
The following tests are available to identify the ASF virus:
- Hemadsorption (HAD) test
- Polymerase chain reaction (PCR)
- Pig inoculation (no longer recommended)
The following tests can be used to test for antibodies in recovering pigs about 8 to 21 days after infection:
- Enzyme-linked immunosorbent assay (ELISA) (preferred test for international trade)
- Indirect fluorescent antibody test (FAT)
- Immunoblotting test
- Counter-immunoelectrophoresis (immunoelectroosmophoresis)
John Beldekas's research on African Swine Fever Virus as a human infection
http://www.keephopealive.org/report10.htmlSpin Magazine on John Beldekas
Florida Pig Farm Poses Riddle
"AIDS victims and pigs stricken with chronic African swine fever have common characteristics, Beldekas said, including fever, abnormally large lymph nodes, skin lesions, immune-related pneumonia, and a reduction of white blood cells. Both diseases can be spread through exposure to infected blood, blood products and semen, Beldekas said, but the animal virus can also be transmitted by infected ticks. Accordingly, they say, the animal virus may somehow be a factor in the transmission of AIDS, which could have spread from infected pigs to humans through tick bites, and then from human to human through sexual contact or direct infection of blood."--By JON NORDHEIMER, SPECIAL TO THE NEW YORK TIMES
1. HIV is a massive scientific fraud. Something akin to a Ponzi scheme. Scientists who challenged the HIV theory of AIDS (the ones who have been thuggishly censored and silenced) turn out to be on the money.
2. Chronic Fatigue Syndrome and Autism (and many other so-called HHV-6 related mysterious epidemics) are part of the so-called AIDS epidemic. Chronic Fatigue Syndrome and Autism both are clearly the results of the ravages of HHV-6.
3. AIDS and Chronic Fatigue Syndrome has been artificially and politically separated into two epidemics. We are living in a period of CFS/AIDS apartheid. So-called AIDS patients have to sit in the back of the HHV-6 epidemic bus while the befuddled HHV-6/CFS patients and HHV-6/Autism victims sit up front. Nobody is well-served.
4. AIDS is not a sexually transmitted disease. That paradigm has set a scapegoating and antigay agenda in place that the public thinks is solidly based on science. It is only based on homophobic and racist nosology, epidemiology and virology. The scientists behind the paradigm are charlatans and crooks.
5. The Centers for Disease Control in Atlanta and the Pasteur Institute in Paris have a great deal in common with the institutions of Nazi medicine. For Blacks, everything these institutions have done in the name of AIDS really constitutes a second Tuskegee Syphilis Experiment.
Elements of a Scientific Ponzi Scheme like the Montagnier-Agut HIV Fraud Ponzi Scheme and HHV-6 Cover-up
A
scientific Ponzi scheme begins with a central seminal or foundational
scientific fraud and is sometimes built on an infrastructure of smaller
scientific frauds. Like the fake dividends issued in a strictly
financial Ponzi scheme, a scientific Ponzi scheme issues fake dividends
in the form of ongoing fraud-based research often framed as
"breakthroughs" and bogus extrapolations which make it look like
everything is above board and that what, in reality, is scientific
fraud, appears to the rest of the scientific community and the public as
good faith progress.
A classic scientific Ponzi scheme like the Montgnier-Agut HIV Fraud Ponzi Scheme and HHV-6 Cover-up include elements like these:
1. Nosological fraud.
2. Epidemiological fraud.
3. Virological fraud.
4. Treatment fraud.
5. Public health policy fraud.
6. Concealment of negative scientific data and paradigm-challenging anomalies.
7. Use of an elite network of "old boys" and pseudo-activist provocateurs to censor critics and whistleblowers.
8. Chronic obscurantism.
9.
If necessary, vigilantism and witch-hunts against any intellectuals,
scientists, or citizens who constitute any form of resistance to the
Ponzi scheme.
10. A subservient scientific press that is used as a conveyor belt for the Ponzi scheme's propaganda.
Everything
always looks like it is working perfectly in a Ponzi scheme, until the
moment comes when someone look at the books and blows the whistle.
Hopefully, that game-changing moment for the Montagnier-Agut HIV Fraud
Ponzi Scheme and HHV-6 Cover-up is coming soon.