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Showing posts from September, 2013

In this study, we detected the viral DNA of Human Herpes Virus 6 (HHV-6) in the sera and cell-free cerebrospinal fluid (CSF) of Chinese multiple sclerosis (MS) patients

http://www.bioportfolio.com/search/T-cell-recall-and-cross-reactivity.html

Possible role of HHV-6 as a trigger of Autoimmune disease

http://www.hindawi.com/journals/tswj/aip/867389/

Chimerix Initiates Phase 3 SUPPRESS Trial of Brincidofovir (CMX001) for Prevention of Cytomegalovirus in Hematopoietic Cell Transplant Recipients

http://www.healthtechnologynet.com/articles/viewarticle.jsp?id=2796030&type=home

Sensitivity of human herpesvirus 6 and other human herpesviruses to the broad-spectrum antiinfective drug artesunate.

http://www.ncbi.nlm.nih.gov/pubmed/19501020

Conditions associated with HHV-6

http://hhv-6foundation.org/conditions-associated-with-hhv-6

Dan Peterson on Antiviral Treatment for HHV-6 (2008)

Video #1 Video #2

Human Herpesvirus 6 Infection of the Gastroduodenal Mucosa

"HHV-6–positive cells and CMV-positive cells were frequently found in the gastroduodenal mucosa of liver transplant recipients and of immunocompetent patients undergoing gastroscopic examination because of dyspeptic symptoms." Leena Halme, Johanna Arola, Krister Höckerstedt, and Irmeli Lautenschlager http://cid.oxfordjournals.org/content/46/3/434.full

Infection of murine oligodendroglial precursor cells with Human Herpesvirus 6 (HHV-6) — establishment of a murine in vitro model

odel David J. Mock et. al. Abstract Background Human Herpesvirus 6 was previously demonstrated to infect human oligodendroglial precursor cells (OPCs) in vitro causing cell cycle arrest and premature differentiation with consequent loss of the precursor pool. Objectives To develop an in vitro murine OPC model to study the cell cycle and differentiation effects of HHV-6 in more readily available, genetically well-defined cells free of the risk of contamination with human herpesviruses. Study design Murine OPCs were exposed to infectious HHV-6A or HHV-6B and analyzed for production of viral transcripts, particles, and replicating virus. FACS analysis and specific markers were used to evaluate effects on cell cycling and differentiation. Results HHV-6 infection of murine OPCs resulted in production of both immediate-early and some late transcripts but no replicating virus by TaqMan quantitative PCR or electron microscopy. Both a specific G1/S cell cycle a...

HHV-6 Virus May Enter Brain via Nose, Say Experts

http://topnews.us/content/242425-hhv-6-virus-may-enter-brain-nose-say-experts

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