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Showing posts from November, 2022

Are chronic strains of African Swine Fever in Germany a threat to human health?

  Pathology of African Swine Fever in Wild Boar Carcasses Naturally Infected with German Virus Variants - PubMed (nih.gov)

Were Masters and Johnson inadvertently warning the world about the Chronic Fatigue Syndrome epidemic in 1988?

  https://www.washingtonpost.com/archive/politics/1988/05/19/public-misled-masters-and-johnson-tell-aids-panel/d724a633-12a2-4c96-8956-61ea4ddca949 /

Will the big question about Long-haul AIDS and Long-haul Covid be the role of KS Inflammatory cytokines?

  Kaposi Sarcoma Inflammatory Cytokine Syndrome (KICS): A Rare but Potentially Treatable Condition - PubMed (nih.gov)

In addition to "Long-haul AIDS," the correction of the CFS/AIDS paradigm may require the new working diagnosis of "Long-haul Kaposi's Sarcoma."

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HHV-8 may hold the key to the real nature of the CFS/AIDS pandemic   A179L, a viral Bcl-2 homologue, targets the core Bcl-2 apoptotic machinery and its upstream BH3 activators with selective binding restrictions for Bid and Noxa - PMC (nih.gov) The apoptosis cascade may be initiated by pathogenic agents such as viruses and is considered as part of the cellular defensive mechanism. Viruses have adapted numerous ways of circumventing this host defensive response, including regulation of endogenous host death receptors and ligands, expression of caspase activation inhibitors, regulation of host Bcl-2 proteins, and expression of viral homologues of Bcl-2 (vBcl-2s) ( Benedict et al., 2002; Polster et al., 2004 ).These viral genes encoding proteins with amino acid sequence similarity to cellular Bcl-2 apoptosis inhibitors have been identified in several viral models including Epstein–Barr virus (EBV) ( Bellows et al., 2002; Henderson et al., 1993 ),  human herpes virus 8 (HHV8) ( Ch...

The link between African Swine Fever and HHV-8, the supposed Kaposi's Sarcoma virus.

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  A179L, a viral Bcl-2 homologue, targets the core Bcl-2 apoptotic machinery and its upstream BH3 activators with selective binding restrictions for Bid and Noxa - PMC (nih.gov) The apoptosis cascade may be initiated by pathogenic agents such as viruses and is considered as part of the cellular defensive mechanism. Viruses have adapted numerous ways of circumventing this host defensive response, including regulation of endogenous host death receptors and ligands, expression of caspase activation inhibitors, regulation of host Bcl-2 proteins, and expression of viral homologues of Bcl-2 (vBcl-2s) ( Benedict et al., 2002; Polster et al., 2004 ).These viral genes encoding proteins with amino acid sequence similarity to cellular Bcl-2 apoptosis inhibitors have been identified in several viral models including Epstein–Barr virus (EBV) ( Bellows et al., 2002; Henderson et al., 1993 ), human herpes virus 8 (HHV8) ( Cheng et al., 1997 ) and African swine fever virus (ASFV) ( Afonso et al....

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Is African Swine Fever a threat to human health in Congo?

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Multiple forms of Kaposi's Sarcoma and endothelial cell dysfunction may be the link between AIDS, Chronic Fatigue Syndrome, and autism.

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