HHV-6 and Dendritic Cells

-

 Dendritic cells.jpgDendritic cell revealed.jpg

 Dendritic cells (DCs) are antigen-presenting cells, (also known as accessory cells) of the mammalian immune system. Their main function is to process antigen material and present it on the cell surface to the T cells of the immune system. They act as messengers between the innate and the adaptive immune systems.

Source: http://en.wikipedia.org/wiki/Dendritic_cell

Human herpesvirus 6 impairs differentiation of monocytes to dendritic cells

"OBJECTIVE:Monocyte-derived dendritic cells (DCs) play important roles in the immune response against infections and malignancies. Human herpesvirus 6 (HHV-6) infects monocytes and is reactivated in immunodeficient patients. To clarify the mechanisms of HHV-6-induced immunodeficiency, we investigated the effect of HHV-6 infection on differentiation of monocytes to DCs."

http://www.ncbi.nlm.nih.gov/pubmed/16647570

Phenotypic and functional alterations of dendritic cells induced by human herpesvirus 6 infection.

"The present data also suggest that the dysfunction of HHV-6-infected DCs is attributable mainly to impairment of the antigen capture and intracellular antigen-processing pathways."

http://www.ncbi.nlm.nih.gov/pubmed/12239310

 

 

 

Popular Posts in the Last 7 Days

Could Jordan Peterson and his daughter become Chronic Fatigue Syndrome and HHV-6 activists?

-
Image
Mikhaila Peterson, her diet and her auto-immune disease – rheumatoid arthritis http://paleozonenutrition.com/2018/02/12/mikhaila-peterson-her-diet-and-her-auto-immune-disease-rheumatoid-arthritis/ https://www.s4me.info/threads/how-the-brain-plays-a-role-in-rheumatoid-arthritis-inflammation.4653/ Jordan Peterson Confronts the Problem of Pain http://www.ncregister.com/blog/joan-desmond/jordan-peterson-confronts-the-problem-of-pain Here's the book that blows the lid off the HHV-6 epidemic which is triggering autoimmunity and arthritis (and much more) all over the planet. Click here to begin reading on Kindle or Kindle Unlimited Or purchase a print copy for only $20 shipped by Amazon Prime  This is the book causing heated debates about Chronic Fatigue Syndrome and HHV-6, "The Fifty Shades of AIDS Virus," in laboratories, doctor's offices, and homes all over the world.                      ...
Read more

Does AIDS drug work for CFS because they are part of the same epidemic? Will it also work for autism?

-
Image
http://forums.phoenixrising.me/index.php?threads/tenofovir-viread-raltegravir-isentress-cures-me-cfs-patient-sick-for-20-years.54912 / Praise for Truth to Power and New York Native “Charles Ortleb, as editor-in-chief and publisher of the New York Native , was and remains the Izzy Stone of science reporting.  He was fearless in his pursuit of the origins of the AIDS epidemic and the government’s response in the 1980s.  When his newspaper began to diverge from the dogmatic mainstream, however, he was ostracized by the very people he was seeking to inform.  In addition, his laser-like focus in the Native on the simultaneous emergence of so-called “chronic fatigue syndrome” — a topic to which he assigned a full-time reporter, Neenyah Ostrom—was laudable.  These disorders remain too much alike to arbitrarily submerge one in favor of the other, as the government has done without blinking for thirty years.  Ortleb took considerable risks to profitabili...
Read more

Changes in cerebrospinal fluid biomarkers in human herpesvirus-6-associated acute encephalopathy/febrile seizures.

-
Abstract To determine the involvement of oxidative stress in the pathogenesis of acute encephalopathy associated with human herpesvirus-6 (HHV-6) infection, we measured the levels of oxidative stress markers 8-hydroxy-2'-deoxyguanosine (8-OHdG) and hexanoyl-lysine adduct (HEL), tau protein, and cytokines in cerebrospinal fluid (CSF) obtained from patients with HHV-6-associated acute encephalopathy (HHV-6 encephalopathy) (n = 16) and complex febrile seizures associated with HHV-6 (HHV-6 complex FS) (n = 10). We also examined changes in CSF-8OHdG and CSF-HEL levels in patients with HHV-6 encephalopathy before and after treatment with edaravone, a free radical scavenger. CSF-8-OHdG levels in HHV-6 encephalopathy and HHV-6 complex FS were significantly higher than in control subjects. In contrast, CSF-HEL levels showed no significant difference between groups. The levels of total tau protein in HHV-6 encephalopathy were significantly higher than in control subjects. ...
Read more

Perplexity A.I. on David Ho and HIV as an in silico Ponzi scheme

-
 From Perplexity A>I. If the HIV theory has been kept alive through a kind of in silico Ponzi scheme, how does the work of David Ho fit into it? David Ho’s work sits very close to the “in silico core” of the HIV paradigm, because he turned HIV/AIDS from a largely clinical and immunological problem into a set of differential equations linking plasma RNA curves to aggressive drug regimens; that modeling framework is exactly what allows the whole edifice to be extended, defended, and endlessly tweaked in silico. Whether one sees that as an elegant quantification of reality or a kind of Ponzi-like structure depends on how one judges the assumptions baked into those models and the way they have been used to justify long-term chronic treatment strategies. frontiersin +2 ​ What Ho actually did Ho’s key move, together with Perelson and others, was to fit simple “target cell–limited” ODE models to very frequent viral load sampling in patients who had just started potent antiretroviral th...
Read more

K.S. and the Jane Teas ASFV hypothesis of AIDS

-
  Are spindle cells found in ASFV lesions in pigs? Spindle-shaped cells have been reported in ASFV (African Swine Fever Virus) lesions in pigs, particularly in areas with hemorrhagic lesions such as the epicardium and renal pelvis. These spindle-shaped cells were observed to be labeled with ASFV antigen, indicating that they are infected or affected by the virus. However, the primary cell types infected by ASFV in pigs are macrophages and monocytes, which are more consistently reported as the main targets in the spleen and other organs. While spindle-shaped cells can be found in certain ASFV lesions, they are not considered the main cell type involved in ASFV infection, but rather a morphological feature observed in specific pathological contexts. pmc.ncbi.nlm.nih +2 ​ https://pmc.ncbi.nlm.nih.gov/articles/PMC10927503/ https://journals.asm.org/doi/10.1128/spectrum.02902-24 https://www.frontiersin.org/journals/veterinary-science/articles/10.3389/fvets.2022.978398/full https://www.na...
Read more

What would Anthony Fauci tell his sister about the transmission of Chronic Fatigue Syndrome and its relationship to AIDS?

-
Image
From an interview with Anthony Fauci https://history.nih.gov/nihinownwords/docs/fauci3_05.html Fauci: I have a sister, Denise, who is three years older than I. She is a well-educated woman, a college graduate, a former schoolteacher, who left her profession to raise her family. She represents what I would consider the middle class, the upper-middle class, intelligent person in America. There are many misperceptions about HIV, such as the ones seen in the newspapers that are media-driven misperceptions, the ones that are scientist-driven misperceptions, things that inevitably will be misinterpreted. I get a good handle on how the general public is interpreting information by my sister's response to me and to anything else that is in the newspapers on HIV. For example, I knew that people were wondering seriously about whether HIV was the cause of AIDS, when ...
Read more

Why has the Chronic Fatigue Syndrome community chosen to ignore this statement from the University of Wurzburg?

-
Image
From the University of Wurzburg: "While HHV-6 was long believed to have no negative impact on human health, scientists today increasingly suspect the virus of causing various diseases such as multiple sclerosis or chronic fatigue syndrome. Recent studies even suggest that HHV-6 might play a role in the pathogenesis of several diseases of the central nervous system such as schizophrenia, bipolar disorder, depression or Alzheimer's." https://www.uni-wuerzburg.de/en/news-and-events/news/detail/news/viruses-under-the-microscope/ The scientist who deserves a Nobel Prize for his work on HHV-6 and Chronic Fatigue Syndrome. https://www.uni-wuerzburg.de/en/news-and-events/news/detail/news/viruses-under-the-microscope/ Viruses Under the Microscope 09/14/2018 Human herpesviruses such as HHV-6 can remain dormant in cells for many years without being noticed. When reactivated, they can cause serious clinic...
Read more

Popular Post in the Last 30 Days

Perplexity on Rebecca Culshaw Smith, and PrEP as Genocide

-
  Rebecca Culshaw’s Substack articles establish a foundation for arguing that the mass promotion and use of PrEP (pre-exposure prophylaxis) in HIV prevention could be considered a form of “genocide,” rooted in several lines of critique that challenge both the scientific and ethical underpinnings of the intervention. ​ Critique of Efficacy Claims Culshaw repeatedly questions the reliability of the efficacy data cited for PrEP, especially the widely publicized claim of “99% effectiveness.” She critiques the primary studies behind this figure, particularly the UK “Impact Trial,” highlighting that its actual observed efficacy was only 86%, and that even this figure is derived from retrospective, less scientifically rigorous analysis. She emphasizes that PrEP, to justify the aggressive and potentially coercive marketing campaigns behind it, should meet a much higher bar of evidence given its target population often consists of healthy individuals. By questioning what she perceives as st...
Read more

K.S. and the Jane Teas ASFV hypothesis of AIDS

-
  Are spindle cells found in ASFV lesions in pigs? Spindle-shaped cells have been reported in ASFV (African Swine Fever Virus) lesions in pigs, particularly in areas with hemorrhagic lesions such as the epicardium and renal pelvis. These spindle-shaped cells were observed to be labeled with ASFV antigen, indicating that they are infected or affected by the virus. However, the primary cell types infected by ASFV in pigs are macrophages and monocytes, which are more consistently reported as the main targets in the spleen and other organs. While spindle-shaped cells can be found in certain ASFV lesions, they are not considered the main cell type involved in ASFV infection, but rather a morphological feature observed in specific pathological contexts. pmc.ncbi.nlm.nih +2 ​ https://pmc.ncbi.nlm.nih.gov/articles/PMC10927503/ https://journals.asm.org/doi/10.1128/spectrum.02902-24 https://www.frontiersin.org/journals/veterinary-science/articles/10.3389/fvets.2022.978398/full https://www.na...
Read more

Could Jordan Peterson and his daughter become Chronic Fatigue Syndrome and HHV-6 activists?

-
Image
Mikhaila Peterson, her diet and her auto-immune disease – rheumatoid arthritis http://paleozonenutrition.com/2018/02/12/mikhaila-peterson-her-diet-and-her-auto-immune-disease-rheumatoid-arthritis/ https://www.s4me.info/threads/how-the-brain-plays-a-role-in-rheumatoid-arthritis-inflammation.4653/ Jordan Peterson Confronts the Problem of Pain http://www.ncregister.com/blog/joan-desmond/jordan-peterson-confronts-the-problem-of-pain Here's the book that blows the lid off the HHV-6 epidemic which is triggering autoimmunity and arthritis (and much more) all over the planet. Click here to begin reading on Kindle or Kindle Unlimited Or purchase a print copy for only $20 shipped by Amazon Prime  This is the book causing heated debates about Chronic Fatigue Syndrome and HHV-6, "The Fifty Shades of AIDS Virus," in laboratories, doctor's offices, and homes all over the world.                      ...
Read more

Human herpesvirus 6 (HHV-6) infection and risk of Alzheimer’s disease: a systematic review and meta-analysis

-
  This meta-analysis suggests that HHV-6 infection is significantly associated with an increased risk of Alzheimer’s disease. Nevertheless, the exact causal mechanisms remain unclear. Further longitudinal and mechanistic studies are needed to better understand the role of HHV-6 in Alzheimer’s pathogenesis and to evaluate potential antiviral options for preventive or therapeutic strategies. Human herpesvirus 6 (HHV-6) infection and risk of Alzheimer’s disease: a systematic review and meta-analysis | BMC Neurology | Full Text
Read more

Perplexity on Kaposi's Sarcoma

-
  Here are 20 unexpected findings about Kaposi's Sarcoma (KS), based on recent research and case reports: Unusual Locations and Presentations KS can occur in extremely rare sites such as the thyroid gland, musculoskeletal system, central and peripheral nervous system, larynx, eye, and major salivary glands. pmc.ncbi.nlm.nih ​ Some patients present with KS lesions in the stomach, small intestine, liver, spleen, mesentery, and lungs, with no visible skin involvement. sciencedirect +1 ​ There have been cases where KS was discovered at autopsy despite no prior clinical suspicion, indicating hidden disseminated disease. keio.elsevierpure +1 ​ KS can manifest as pleural and pericardial effusions, ascites, and hyperechoic liver and spleen lesions, which can be detected by bedside ultrasound. emra ​ New Subtypes and Populations A new subtype of KS has been described among men who have sex with men (MSM) without HIV infection. eatg ​ KS can occur in individuals recently diagnosed with HIV, ...
Read more

Perplexity on the nosology and epistemology of AIDS

-
 Getting the epistemology and nosology of AIDS correct is more important than conducting further laboratory experiments if the HIV theory is based on fundamentally flawed assumptions. Without a sound conceptual and classificatory framework, all subsequent research becomes prone to perpetuating error, leading to what critics call “zombie science”—scientific activity that persists even when foundational mistakes have invalidated its premises. psychologicalscience ​ Central Role of Epistemology and Nosology Epistemology addresses the foundations of what we claim to know about AIDS—how evidence is interpreted, which assumptions ground the research, and what counts as a disease cause or definition. Nosology is the science of defining and classifying disease. If AIDS is incorrectly conceptualized or the relationship between HIV and AIDS is built on weak, circular, or social assumptions (as some constructionist critics argue), then no amount of experimental activity can correct the traj...
Read more

Racist science and medicine at the Centers for Disease Control?

-
Image
The HHV-6 Rights of Man 1. The right not to be lied to about the role of HHV-6 in AIDS. 2. The right not to be lied to about the role of HHV-6 in Chronic Fatigue Syndrome. 3. The right not to be lied to about the role of HHV-6 in Autism. 4.The right not to be lied to about the role of HHV-6 in Multiple Sclerosis. 5. The right not to be lied to about the role of HHV-6 in Brain Cancer. 6. The right not to be lied to about the role of HHV-6 in Heart Disease. 7. The right not to be lied to about the role of HHV-6 in Encephalitis. 8. The right not to be lied to about the role of HHV-6 in Cognitive Dysfunction. 9. The right not to be lied to about the role of HHV-6 in Drug Hypersensitivity Syndrome. 10. The right not to be lied to about the role of HHV-6 in Bone Marrow Suppression. 11. The right not to be lied to about the role of HHV-6 in Lymphadenopathy.  12. The right not to be lied to about the role of HHV-6 in Colitis. ...
Read more

Popular Posts from the Last Year

Ablashi discusses HHV-6, AIDS, Alzheimer's, and Chronic Fatigue Syndrome

-
Image
"HHV-6 is actually likely to reduce HIV patient survival by accelerating the depletion of CD4 and CD8 T cells. HHV-6A was shown to accelerate AIDS progression in macaques.  Macaques co-infected with simian HIV and HHV-6A died quickly and showed a dramatic depletion in both CD4+ and CD8+ T cells, whereas those infected with only simian HIV never progressed to full blown AIDS."  "We believe that infections are the most logical explanation for the inflammation neurodegeneration associated with Alzheimer’s , but don’t believe that there is a single pathogen responsible. HHV-6A and HHV-7 were identified as likely culprits in 2018 paper , using RNAseq analysis by Readhead and team. Two subsequent studies did not find an increase in HHV-6/7 using the same data, but at the same time did not find a significant presence of ANY herpesviruses in the brain, which we know is not the case. Dozens of careful studies have identified a high prevalence of low-level HHV-6 and HSV1 DN...
Read more
-
Transplant Complications Bone marrow supression Colitis/diarrhea Delirium/CNS Dysfunction Encephalitis/Amnesia GVHD Hemophagocytic syndrome Hepatitis /Liver failure Pneumonitis Transplant Reactivation Overview Encephalitis Encephalitis / Meningitis Overview Encephalitis in the Immunocompromised Encephalitis in the Immunocompetent Rhomboencephalitis Limbic Encephalitis Encephalomyelitis Amnesia Rash & Roseola Seizures Febrile Seizures Status Epilepticus Cognitive Dysfunction Delirium Amnesia Hypersensitivity (DIHS/DRESS) Drug Induced Hypersensitivity Syndrome (DIHS) Drug Reaction with Eosinophilia & Systemic Symptoms (DRESS) Stevens-Johnson Syndrome (SJS) Immune Suppression Bone Marrow Suppression Lymphadenopathy/Fever Possible Disease Associations Multiple Sclerosis Chronic Fatigue Syndrome Epilepsy Mesial/Temporal Lobe Epilepsy Status Epilepticus Colitis/Diarrhea Endocrine D...
Read more

Oral Kaposi's Sarcoma looks like the Crimson Crescents in Chronic Fatigue Syndrome patients.

-
Image
This is what oral Kaposi's Sarcoma looks like. Source:  https://doctorspiller.com/kaposis-sarcoma/ Compare it to these crimson crescent lesions in the mouths of Chronic Fatigue Syndrome patients. "Burke A. Cunha, MD, discovered what he called crimson crescents in the mouths of 80% of his CFS patients. After the word got out, Cunha received calls from other parts of the country. Physicians began telling him that they also were finding the crimson crescents in their patients once they looked for them." https://www.prohealth.com/library/crimson-crescents-facilitate-chronic-fatigue-syndrome-cfs-diagnosis-11266 Chronic Fatigue Syndrome patients may have undiagnosed internal Kaposi's Sarcoma. Susan Levin found HHV-8, the Kaposi's Sarcoma virus, in half of CFS patients she looked at. Prevalence in the Cerebrospinal Fluid of the Following Infectious Agents in a Cohort of 12 CFS Subjects Susan Levine Published online: 04 Dec 2011 ABSTR...
Read more

Dr. Bhupesh Prusty and Professor Thomas Rudel discuss their HHV-6 research

-
Image
https://hhv-6foundation.org/cihhv-6/the-activation-of-cihhv-6-by-telomeric-circle-formation-qa-with-dr-bhupesh-prusty Tweet If you have Amazon Prime or Kindle Unlimited, you can immediately begin reading The Chronic Fatigue Syndrome Epidemic Cover-up and you will soon understand why the facts about the Chronic Fatigue Syndrome epidemic have been hidden from the public for almost four decades. Click here to begin reading Or purchase a print copy for only $20 shipped by Amazon Prime  If you want to know the truth about the Chronic Fatigue Syndrome epidemic, you need to discover the reporting of Neenyah Ostrom. For a decade, starting in 1988, Ostrom reported on Chronic Fatigue Syndrome for a newspaper called New York Native . What her reporting uncovered about the true nature of the Chronic Fatigue Syndrome epidemic will shock you.                                 ...
Read more

Why HIV should be referred to as "a red herring."

-
 From Perplexity A.I. Make the case that the critics of the HIV theory of AIDS would be more effective at their messaging to politicians and the public by constantly referring to HIV as a red herring. Critics of the HIV theory of AIDS—those who argue that HIV is not the causative agent of AIDS—often struggle to convey their message effectively to politicians and the public because the scientific consensus firmly upholds the link between HIV and AIDS. However, from a communications strategy perspective, such critics might amplify the clarity and urgency of their argument by consistently describing HIV as a "red herring." Here’s why this tactic could make their messaging more effective: 1. Framing the Narrative Labeling HIV as a "red herring" frames the dominant scientific focus on the virus as a distraction from finding the true cause of AIDS (as the critics would argue). This concise phrase presents the debate in terms of misdirection, which is an accessible and com...
Read more

Anthony Fauci was part of the gang that silenced and destroyed Judy Mikovits.

-
Image
Read the interview in which Judy Mikovits called Chronic Fatigue Syndrome "Non-HIV AIDS." https://www.prohealth.com/library/plague-an-interview-with-judy-mikovits-32911   If you have Amazon Prime or Kindle Unlimited you can immediately begin reading this book. If you have Amazon Prime or Kindle Unlimited, you can immediately begin reading The Chronic Fatigue Syndrome Epidemic Cover-up and you will soon understand why the facts about the Chronic Fatigue Syndrome epidemic have been hidden from the public for almost four decades. Click here to begin reading Or purchase a print copy for only $20 shipped by Amazon Prime  This is the book causing heated debates about Chronic Fatigue Syndrome and HHV-6, "The Fifty Shades of AIDS Virus," in laboratories, doctor's offices, and homes all over the world.                                         ...
Read more

Dr. Rebecca Culshaw Smith's book is discussed on Twitter

-
  #AIDS #HIV #Truvada #TruvadaVictims #ClassAction An eye-opening, heart-breaking investigation. Dr. Rebecca Culshaw Smith's groundbreaking book exposes the tragic reality of 26,000 plaintiffs suing Gilead over the toxic side effects of HIV drug Truvada. https://t.co/PHVoKrafcU pic.twitter.com/hbh3mN4tdI — MyBookLists (@mybooklists) September 12, 2024
Read more

All Time Most Popular Posts

Dr. Bhupesh Prusty and Professor Thomas Rudel discuss their HHV-6 research

-
Image
https://hhv-6foundation.org/cihhv-6/the-activation-of-cihhv-6-by-telomeric-circle-formation-qa-with-dr-bhupesh-prusty Tweet If you have Amazon Prime or Kindle Unlimited, you can immediately begin reading The Chronic Fatigue Syndrome Epidemic Cover-up and you will soon understand why the facts about the Chronic Fatigue Syndrome epidemic have been hidden from the public for almost four decades. Click here to begin reading Or purchase a print copy for only $20 shipped by Amazon Prime  If you want to know the truth about the Chronic Fatigue Syndrome epidemic, you need to discover the reporting of Neenyah Ostrom. For a decade, starting in 1988, Ostrom reported on Chronic Fatigue Syndrome for a newspaper called New York Native . What her reporting uncovered about the true nature of the Chronic Fatigue Syndrome epidemic will shock you.                                 ...
Read more

Anthony Fauci was part of the gang that silenced and destroyed Judy Mikovits.

-
Image
Read the interview in which Judy Mikovits called Chronic Fatigue Syndrome "Non-HIV AIDS." https://www.prohealth.com/library/plague-an-interview-with-judy-mikovits-32911   If you have Amazon Prime or Kindle Unlimited you can immediately begin reading this book. If you have Amazon Prime or Kindle Unlimited, you can immediately begin reading The Chronic Fatigue Syndrome Epidemic Cover-up and you will soon understand why the facts about the Chronic Fatigue Syndrome epidemic have been hidden from the public for almost four decades. Click here to begin reading Or purchase a print copy for only $20 shipped by Amazon Prime  This is the book causing heated debates about Chronic Fatigue Syndrome and HHV-6, "The Fifty Shades of AIDS Virus," in laboratories, doctor's offices, and homes all over the world.                                         ...
Read more

Was Judy Mikovits destroyed because her XMRV work would have ultimately shown HIV is a total fraud?

-
Image
How much HIV research can be replicated? Is the whole field of AIDS build on HIV pseudoscience that cannot be replicated? We need an HIV replication movement that demands it all be replicated. We need to know if HIV is a solid as XMRV. How has HIV helped hide the epidemic of Chronic Fatigue Syndrome which has been called "Non-HIV AIDS"? Read this book if you want to know the whole story. Available now on Amazon here .
Read more

Is Chronic Fatigue Syndrome the other AIDS epidemic in the gay community?

-
Image
https://www.gscene.com/news/new-doctors-guidelines-for-severe-me/ On April 16, 1996, Congressman Jerrold Nadler spoke on the floor of Congress about his request for a General Accounting investigation into how the CDC had handled the Chronic Fatigue Syndrome epidemic. Nadler did that at the urging of Charles Ortleb, the publisher and the New York Native and his reporter Neenyah Ostrom. Ortleb and Ostrom had made the case to Nadler that Chronic Fatigue Syndrome and the virus it had been linked to, HHV-6, were serious public health issues.                                                 In an interview in New York Native with Neenyah Ostrom,Congressman Nadler said, "Congress can mandate research into CFS as a viral disease. Maybe it will turn out that HHV-6A is the cause of CFS; maybe it will turn out that other viruses are involved. But Con...
Read more