"Ablashi asserts that HHV-6A is the predominant strain in CFS, multiple sclerosis (MS) and AIDS patients.."
"In vitro tests indicate HHV-6 can infect many different cell types including dendritic cells, NK cells and fibroblasts as well as liver, epithelial and endothelial cells and the glial cells in the brain (astrocytes, oligodendrocytes, microglia). The HHV6 genome has been detected in brain, liver, skin, lungs, kidneys, heart, tonsils, salivary glands, esophagus, etc. It is believed to make its way to the brain on board T lymphocytes able to penetrate the blood:brain barrier.
Although HHV-6 is able to infect many cells, in only a few is it able to progress to the ‘lytic phase’. (The lytic phase occurs when a virus enters the cells and uses its DNA to produce virions which usually end up killing the cell, allowing them to escape en masse.) HHV-6 can replicate in B cells and NK cells but productive HHV-6 infection is believed to be confined to T lymphocytes, in particular in T-helper (CD4+) cells, monocytes/macrophages, neurons, astrocytes and oligodendrocytes (Kakimoto et al. 2002, Grivel et al. 2003, Fotheringham et al. 2008)).
http://phoenixrising.me/research-2/the-pathogens-in-chronic-fatigue-syndrome-mecfs/hhv-6-and-chronic-fatigue-syndrome-mecfs-an-overview/human-herpes-virus-6-hhv-6-and-disease