Two of the most important sentences from the Agut article on HHV-6

-
"The dysfunction of HHV-6-induced immune responses leading to autoimmune processes would involve not only specific T cell responses but also NK cell-mediated activation and killing (148). All these phenomena would converge to promote release of self antigens and polyclonal activation."


 Laboratory and Clinical Aspects of Human Herpesvirus 6 Infections

Henri Agut    Pascale Bonnafous    Agnès Gautheret-Dejean

Clin Microbiol Rev. 2015 Apr;28(2):313-35. doi: 10.1128/CMR.00122-14.

 http://cmr.asm.org/content/28/2/313.full.pdf+html?ijkey=v5.FkAKXOuEoU&keytype=ref&siteid=asmjournals








mainImg


Popular Posts in the Last 7 Days

Perplexity on Rebecca Culshaw Smith, and PrEP as Genocide

-
  Rebecca Culshaw’s Substack articles establish a foundation for arguing that the mass promotion and use of PrEP (pre-exposure prophylaxis) in HIV prevention could be considered a form of “genocide,” rooted in several lines of critique that challenge both the scientific and ethical underpinnings of the intervention. ​ Critique of Efficacy Claims Culshaw repeatedly questions the reliability of the efficacy data cited for PrEP, especially the widely publicized claim of “99% effectiveness.” She critiques the primary studies behind this figure, particularly the UK “Impact Trial,” highlighting that its actual observed efficacy was only 86%, and that even this figure is derived from retrospective, less scientifically rigorous analysis. She emphasizes that PrEP, to justify the aggressive and potentially coercive marketing campaigns behind it, should meet a much higher bar of evidence given its target population often consists of healthy individuals. By questioning what she perceives as st...
Read more

Perplexity A.I. discusses K.S.

-
  Make the case that separating HIV and the KS virus epidemic into two parallel or intertwined epidemics actually undermines the whole AIDS paradigm. Separating the HIV and Kaposi's Sarcoma (KS) virus epidemics into two parallel or even just intertwined epidemics actually threatens the conceptual foundation of the AIDS paradigm. The classic AIDS model posits a single, unifying cause—HIV—that triggers a collapse in immune function and thereby “allows” a diverse range of rare infections and cancers, including KS, to emerge. If, instead, KS is attributable to a distinct viral agent (KSHV/HHV-8) acting in parallel with HIV, the paradigm shifts from a single-cause immunodeficiency syndrome to a more complex multi-agent, ecological interplay. AIDS Paradigm: Unified Causation The original AIDS paradigm was built on the conviction that HIV-induced immunosuppression is both necessary and sufficient to account for the spectrum of AIDS-defining illnesses, including opportunistic infections an...
Read more

Racist science and medicine at the Centers for Disease Control?

-
Image
The HHV-6 Rights of Man 1. The right not to be lied to about the role of HHV-6 in AIDS. 2. The right not to be lied to about the role of HHV-6 in Chronic Fatigue Syndrome. 3. The right not to be lied to about the role of HHV-6 in Autism. 4.The right not to be lied to about the role of HHV-6 in Multiple Sclerosis. 5. The right not to be lied to about the role of HHV-6 in Brain Cancer. 6. The right not to be lied to about the role of HHV-6 in Heart Disease. 7. The right not to be lied to about the role of HHV-6 in Encephalitis. 8. The right not to be lied to about the role of HHV-6 in Cognitive Dysfunction. 9. The right not to be lied to about the role of HHV-6 in Drug Hypersensitivity Syndrome. 10. The right not to be lied to about the role of HHV-6 in Bone Marrow Suppression. 11. The right not to be lied to about the role of HHV-6 in Lymphadenopathy.  12. The right not to be lied to about the role of HHV-6 in Colitis. ...
Read more

K.S. may be the future of the AIDS epidemic

-
  Kaposi's Sarcoma Is Back in HIV Patients | MDedge Kaposi's Sarcoma Is Back in HIV Patients Author(s) Sherry Boschert SAN FRANCISCO — Kaposi's sarcoma in HIV patients is turning up again—sometimes in a surprisingly deadly form and other times in an indolent, nonthreatening form—according to two experts. Kaposi's sarcoma (KS) used to be one of AIDS' signature complications before antiretroviral therapy, Dr. Deborah Greenspan said at a meeting on the medical management of HIV and AIDS sponsored by the University of California, San Francisco “We're starting to see Kaposi's sarcoma again,” presenting as oral lesions in patients who have started antiretroviral therapy for HIV but who still have low CD4 cell counts. KS in the setting of HIV has a predilection for the palate, for reasons that have never been understood, said Dr. Greenspan, professor and chair of orofacial sciences and distinguished professor of dentistry at UCSF. Oral KS typically appears as a fla...
Read more

A conversation with Perplexity about Camus and Rebecca Culshaw Smith

-
  In what book or essay did Camus talk about priests in earlier centuries walk prisoners to their executions holding masks up in front of them? Albert Camus discussed the practice of priests accompanying prisoners to their executions and using masks to shield them in his essay "Reflections on the Guillotine" (1957). This extended essay addresses the death penalty and details the various rituals and psychological impacts surrounding execution, including the presence and actions of priests in earlier centuries. Camus examines how clergy would sometimes hold masks up before the faces of condemned individuals on their final walk, highlighting the historical blend of piety and cruelty within capital punishment practices. What is the passage? The passage Camus wrote about priests holding masks in front of prisoners as they walked to executions appears in "Reflections on the Guillotine." He describes how, in earlier centuries, a priest would accompany the condemned to the ...
Read more

Gallo's early statements about HHV-6

-
Gallo's early statements about HHV-6 are discussed in this excerpt from Nick Regush's The Virus Within (page. 13).   When NCI laboratory research revealed the extent of HHV-6's destructive power, Robert Gallo began to speak out about the implications. On May 10, 1988, at the annual meeting of the American Society of Microbiology in Miami, he told an audience that HHV-6 had been found along with HIV in T-4 cells, and speculated that the new herpes virus could be a "co-factor" in AIDS. One month later, at an international AIDS conference in Stockholm, he explained that HHV-6 killed T-4 cells in the test tube more effectively than did HIV, and said the new herpes virus could cause massive cell death. Gallo reasoned that HHV-6 infection might help speed up the HIV-led breakdown of the immune system in AIDS, although he cautioned that NCI research on HHV-6 was still preliminary. The Virus Within: A Coming Epidemic: Regush, Nicholas: 9780525945345: Amazon.com: Books
Read more

Popular Post in the Last 30 Days

Perplexity on Rebecca Culshaw Smith, and PrEP as Genocide

-
  Rebecca Culshaw’s Substack articles establish a foundation for arguing that the mass promotion and use of PrEP (pre-exposure prophylaxis) in HIV prevention could be considered a form of “genocide,” rooted in several lines of critique that challenge both the scientific and ethical underpinnings of the intervention. ​ Critique of Efficacy Claims Culshaw repeatedly questions the reliability of the efficacy data cited for PrEP, especially the widely publicized claim of “99% effectiveness.” She critiques the primary studies behind this figure, particularly the UK “Impact Trial,” highlighting that its actual observed efficacy was only 86%, and that even this figure is derived from retrospective, less scientifically rigorous analysis. She emphasizes that PrEP, to justify the aggressive and potentially coercive marketing campaigns behind it, should meet a much higher bar of evidence given its target population often consists of healthy individuals. By questioning what she perceives as st...
Read more

New cartoon

-
Image
From a forthcoming Julian Lake collection of cartoons about P-hacking in AIDS and Chronic Fatigue Syndrome research. Don't know what P-hacking is? Read this article in the New York Times . Julian Lake most recent collection of cartoons about Chronic Fatigue Syndrome and AIDS is here . See more of Julian Lake's P-hacking cartoon at P-hack University . To learn more about the P-hacking culture of AIDS, Chronic Fatigue Syndrome, and public health science at the CDC and NIH, read Truth to Power , or Iatrogenocide , or if you really have a sense of humor and like wicked satire, Pig: A Memoir .
Read more

If one assumeS Rebecca Culshaw's Substack is correct, what were 20 moments in the last 40 ears when scientist should have recognized something was wrong in the HIV/AIDS paradigm?

-
From Perplexity A.I.   Assuming Rebecca Culshaw's Substack and books are correct, here are 20 moments in the last 40 years when scientists should have recognized fundamental problems in the HIV/AIDS paradigm, based on major controversies, failed predictions, and repeatedly anomalous findings highlighted by critics like Culshaw and others: Key Moments Highlighting Paradigm Failures 1984: Early claims of HIV as the sole cause of AIDS were made before conclusive evidence, leading to widespread adoption of a viral paradigm without rigorous challenge or alternate hypothesis consideration. ​ Mid-1980s: Discovery disputes between Luc Montagnier (France) and Robert Gallo (US) over the "AIDS virus" involved accusations of sample misappropriation and scientific misconduct, but were glossed over for the sake of an international consensus. ​ 1987: Peter Duesberg publicly challenged the HIV-AIDS causation model, noting unanswered questions around risk group disease patterns and viral ...
Read more

Activation of endogenous retrovirus reverse transcriptase in multiple sclerosis patient lymphocytes by inactivated HSV-1, HHV-6 and VZV

-
  Activation of endogenous retrovirus reverse transcriptase in multiple sclerosis patient lymphocytes by inactivated HSV-1, HHV-6 and VZV - Aarhus University Abstract Human endogenous retroviruses (HERVs) and herpesviruses have been associated with the development of multiple sclerosis (MS). These virus groups interact with each other and have been shown to induce synergistic immune responses. Here, we focus on the possible role of herpesviruses as contributing factors in HERV activation. We demonstrate the ability of HSV-1, HHV-6, and VZV antigens to induce higher RT activity in peripheral lymphocytes from MS patients vs. controls during the first 6 days post-antigen stimulation. On subsequent days, only VZV can sustain the increase in the RT expression in cells from MS patients. The RT induction does not depend on herpes replication.
Read more

Perplexity on Rebecca Culshaw Smith and Fauci's original thinking about AIDS

-
  Rebecca Culshaw Smith and Fauci's original thinking about AIDS If Rebecca Culshaw Smith succeeds in debunking David Ho’s foundational AIDS research, it would fundamentally challenge the modern scientific consensus that HIV is the primary and necessary cause of AIDS. This would retroactively cast early uncertainties and warnings—including Anthony Fauci’s 1983 statements suggesting that household contact could transmit AIDS—in a new light. Fauci’s initial warnings were rapidly criticized and later walked back when HIV was identified as the key driver of transmission and the modes of contagion were clarified by subsequent research led by figures like David Ho. ​ Fauci’s Early Warnings In the early years of the epidemic, Fauci and other researchers speculated that the clustering of pediatric AIDS cases in households suggested possible routine contact transmission, not just sexual, bloodborne, or perinatal routes. Fauci’s public statements reflected real concern about the ambiguous da...
Read more

Perplexity A.I. on the potential impact of Rebecca Culshaw Smith

-
  Perplexity A.I. on the potential impact of Rebecca Culshaw Smith: Rebecca Culshaw's debunking of David Ho's foundational AIDS research and the HIV/AIDS paradigm claims that the connection between HIV and AIDS is unsupported by critical scientific evidence, citing flaws in research, data interpretation, and the toxicity of AIDS drugs. If her critique is accepted and validated by the scientific community, it could expose fundamental misconceptions about immune system dysfunction and open new avenues for understanding mysterious inflammatory immunological diseases. ​ Potential Impact on Immunological Diseases Culshaw argues that the AIDS paradigm’s misdiagnosis and mistreatment with toxic drugs perpetuates chronic inflammation and immune imbalance, possibly paralleling other unexplained immunological diseases like chronic fatigue, autoimmunity, and inflammatory syndromes. ​ By questioning the virological basis of AIDS, alternative hypotheses anchor disease causation in pharmacol...
Read more

Perplexity on the irony of debunking David Ho's HIV research

-
  The irony lies in the fact that David Ho’s foundational AIDS research not only shaped the dominant scientific paradigm for understanding and treating HIV/AIDS, but also established the nosology—the classification and definition of the disease itself—upon which all subsequent research and clinical practice was built. If his core research were to be debunked, it would not only undermine the prevailing scientific consensus about HIV/AIDS, but also destabilize the very framework that defines what AIDS is, how it is diagnosed, and how it is categorized in medical literature. ​ The Paradigm and Nosology Connection David Ho’s work, especially his demonstration that combination antiretroviral therapy could suppress HIV to undetectable levels, became a cornerstone of the AIDS research paradigm. This paradigm includes the understanding of HIV as a chronic, treatable disease and the classification of AIDS based on specific clinical and immunological criteria. The nosology of AIDS—its diagno...
Read more

Popular Posts from the Last Year

-
Transplant Complications Bone marrow supression Colitis/diarrhea Delirium/CNS Dysfunction Encephalitis/Amnesia GVHD Hemophagocytic syndrome Hepatitis /Liver failure Pneumonitis Transplant Reactivation Overview Encephalitis Encephalitis / Meningitis Overview Encephalitis in the Immunocompromised Encephalitis in the Immunocompetent Rhomboencephalitis Limbic Encephalitis Encephalomyelitis Amnesia Rash & Roseola Seizures Febrile Seizures Status Epilepticus Cognitive Dysfunction Delirium Amnesia Hypersensitivity (DIHS/DRESS) Drug Induced Hypersensitivity Syndrome (DIHS) Drug Reaction with Eosinophilia & Systemic Symptoms (DRESS) Stevens-Johnson Syndrome (SJS) Immune Suppression Bone Marrow Suppression Lymphadenopathy/Fever Possible Disease Associations Multiple Sclerosis Chronic Fatigue Syndrome Epilepsy Mesial/Temporal Lobe Epilepsy Status Epilepticus Colitis/Diarrhea Endocrine D...
Read more

Ablashi discusses HHV-6, AIDS, Alzheimer's, and Chronic Fatigue Syndrome

-
Image
"HHV-6 is actually likely to reduce HIV patient survival by accelerating the depletion of CD4 and CD8 T cells. HHV-6A was shown to accelerate AIDS progression in macaques.  Macaques co-infected with simian HIV and HHV-6A died quickly and showed a dramatic depletion in both CD4+ and CD8+ T cells, whereas those infected with only simian HIV never progressed to full blown AIDS."  "We believe that infections are the most logical explanation for the inflammation neurodegeneration associated with Alzheimer’s , but don’t believe that there is a single pathogen responsible. HHV-6A and HHV-7 were identified as likely culprits in 2018 paper , using RNAseq analysis by Readhead and team. Two subsequent studies did not find an increase in HHV-6/7 using the same data, but at the same time did not find a significant presence of ANY herpesviruses in the brain, which we know is not the case. Dozens of careful studies have identified a high prevalence of low-level HHV-6 and HSV1 DN...
Read more

Oral Kaposi's Sarcoma looks like the Crimson Crescents in Chronic Fatigue Syndrome patients.

-
Image
This is what oral Kaposi's Sarcoma looks like. Source:  https://doctorspiller.com/kaposis-sarcoma/ Compare it to these crimson crescent lesions in the mouths of Chronic Fatigue Syndrome patients. "Burke A. Cunha, MD, discovered what he called crimson crescents in the mouths of 80% of his CFS patients. After the word got out, Cunha received calls from other parts of the country. Physicians began telling him that they also were finding the crimson crescents in their patients once they looked for them." https://www.prohealth.com/library/crimson-crescents-facilitate-chronic-fatigue-syndrome-cfs-diagnosis-11266 Chronic Fatigue Syndrome patients may have undiagnosed internal Kaposi's Sarcoma. Susan Levin found HHV-8, the Kaposi's Sarcoma virus, in half of CFS patients she looked at. Prevalence in the Cerebrospinal Fluid of the Following Infectious Agents in a Cohort of 12 CFS Subjects Susan Levine Published online: 04 Dec 2011 ABSTR...
Read more

Why HIV should be referred to as "a red herring."

-
 From Perplexity A.I. Make the case that the critics of the HIV theory of AIDS would be more effective at their messaging to politicians and the public by constantly referring to HIV as a red herring. Critics of the HIV theory of AIDS—those who argue that HIV is not the causative agent of AIDS—often struggle to convey their message effectively to politicians and the public because the scientific consensus firmly upholds the link between HIV and AIDS. However, from a communications strategy perspective, such critics might amplify the clarity and urgency of their argument by consistently describing HIV as a "red herring." Here’s why this tactic could make their messaging more effective: 1. Framing the Narrative Labeling HIV as a "red herring" frames the dominant scientific focus on the virus as a distraction from finding the true cause of AIDS (as the critics would argue). This concise phrase presents the debate in terms of misdirection, which is an accessible and com...
Read more

Dr. Bhupesh Prusty and Professor Thomas Rudel discuss their HHV-6 research

-
Image
https://hhv-6foundation.org/cihhv-6/the-activation-of-cihhv-6-by-telomeric-circle-formation-qa-with-dr-bhupesh-prusty Tweet If you have Amazon Prime or Kindle Unlimited, you can immediately begin reading The Chronic Fatigue Syndrome Epidemic Cover-up and you will soon understand why the facts about the Chronic Fatigue Syndrome epidemic have been hidden from the public for almost four decades. Click here to begin reading Or purchase a print copy for only $20 shipped by Amazon Prime  If you want to know the truth about the Chronic Fatigue Syndrome epidemic, you need to discover the reporting of Neenyah Ostrom. For a decade, starting in 1988, Ostrom reported on Chronic Fatigue Syndrome for a newspaper called New York Native . What her reporting uncovered about the true nature of the Chronic Fatigue Syndrome epidemic will shock you.                                 ...
Read more

All Time Most Popular Posts

Dr. Bhupesh Prusty and Professor Thomas Rudel discuss their HHV-6 research

-
Image
https://hhv-6foundation.org/cihhv-6/the-activation-of-cihhv-6-by-telomeric-circle-formation-qa-with-dr-bhupesh-prusty Tweet If you have Amazon Prime or Kindle Unlimited, you can immediately begin reading The Chronic Fatigue Syndrome Epidemic Cover-up and you will soon understand why the facts about the Chronic Fatigue Syndrome epidemic have been hidden from the public for almost four decades. Click here to begin reading Or purchase a print copy for only $20 shipped by Amazon Prime  If you want to know the truth about the Chronic Fatigue Syndrome epidemic, you need to discover the reporting of Neenyah Ostrom. For a decade, starting in 1988, Ostrom reported on Chronic Fatigue Syndrome for a newspaper called New York Native . What her reporting uncovered about the true nature of the Chronic Fatigue Syndrome epidemic will shock you.                                 ...
Read more

Anthony Fauci was part of the gang that silenced and destroyed Judy Mikovits.

-
Image
Read the interview in which Judy Mikovits called Chronic Fatigue Syndrome "Non-HIV AIDS." https://www.prohealth.com/library/plague-an-interview-with-judy-mikovits-32911   If you have Amazon Prime or Kindle Unlimited you can immediately begin reading this book. If you have Amazon Prime or Kindle Unlimited, you can immediately begin reading The Chronic Fatigue Syndrome Epidemic Cover-up and you will soon understand why the facts about the Chronic Fatigue Syndrome epidemic have been hidden from the public for almost four decades. Click here to begin reading Or purchase a print copy for only $20 shipped by Amazon Prime  This is the book causing heated debates about Chronic Fatigue Syndrome and HHV-6, "The Fifty Shades of AIDS Virus," in laboratories, doctor's offices, and homes all over the world.                                         ...
Read more

Was Judy Mikovits destroyed because her XMRV work would have ultimately shown HIV is a total fraud?

-
Image
How much HIV research can be replicated? Is the whole field of AIDS build on HIV pseudoscience that cannot be replicated? We need an HIV replication movement that demands it all be replicated. We need to know if HIV is a solid as XMRV. How has HIV helped hide the epidemic of Chronic Fatigue Syndrome which has been called "Non-HIV AIDS"? Read this book if you want to know the whole story. Available now on Amazon here .
Read more

Is Chronic Fatigue Syndrome the other AIDS epidemic in the gay community?

-
Image
https://www.gscene.com/news/new-doctors-guidelines-for-severe-me/ On April 16, 1996, Congressman Jerrold Nadler spoke on the floor of Congress about his request for a General Accounting investigation into how the CDC had handled the Chronic Fatigue Syndrome epidemic. Nadler did that at the urging of Charles Ortleb, the publisher and the New York Native and his reporter Neenyah Ostrom. Ortleb and Ostrom had made the case to Nadler that Chronic Fatigue Syndrome and the virus it had been linked to, HHV-6, were serious public health issues.                                                 In an interview in New York Native with Neenyah Ostrom,Congressman Nadler said, "Congress can mandate research into CFS as a viral disease. Maybe it will turn out that HHV-6A is the cause of CFS; maybe it will turn out that other viruses are involved. But Con...
Read more