Another smoking gun pointing to HHV-6 as the definitive cause of Chronic Fatigue Syndrome?
Mitochondrial DNA variants correlate with symptoms in myalgic
encephalomyelitis/chronic fatigue syndrome
http://www.translational-medicine.com/content/14/1/19
Human herpesvirus 6A induces apoptosis of HSB-2 cells via a mitochondrion-related caspase pathway
"Apoptosis plays an important role in the pathogenesis of viral infections. In this study, we investigated the cell death processes during productive HHV-6A infection and the underlying mechanisms. Annexin V-PI staining and electron microscopy indicated that HHV-6A is a strong inducer of apoptosis. HHV-6A infection decreased mitochondrial transmembrane potential and led to morphological changes of mitochondria"
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596692/
encephalomyelitis/chronic fatigue syndrome
http://www.translational-medicine.com/content/14/1/19
Human herpesvirus 6A induces apoptosis of HSB-2 cells via a mitochondrion-related caspase pathway
"Apoptosis plays an important role in the pathogenesis of viral infections. In this study, we investigated the cell death processes during productive HHV-6A infection and the underlying mechanisms. Annexin V-PI staining and electron microscopy indicated that HHV-6A is a strong inducer of apoptosis. HHV-6A infection decreased mitochondrial transmembrane potential and led to morphological changes of mitochondria"
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596692/