Is immune dysfunction the context and cofactor of Zika Disease?

-
"Let’s stop blaming viral mutation rates for altered patterns of virus spread and pathogenesis. More likely determinants include susceptibility of human populations, immune status . . . ."
http://www.virology.ws/

Popular Posts in the Last 7 Days

-
Transplant Complications Bone marrow supression Colitis/diarrhea Delirium/CNS Dysfunction Encephalitis/Amnesia GVHD Hemophagocytic syndrome Hepatitis /Liver failure Pneumonitis Transplant Reactivation Overview Encephalitis Encephalitis / Meningitis Overview Encephalitis in the Immunocompromised Encephalitis in the Immunocompetent Rhomboencephalitis Limbic Encephalitis Encephalomyelitis Amnesia Rash & Roseola Seizures Febrile Seizures Status Epilepticus Cognitive Dysfunction Delirium Amnesia Hypersensitivity (DIHS/DRESS) Drug Induced Hypersensitivity Syndrome (DIHS) Drug Reaction with Eosinophilia & Systemic Symptoms (DRESS) Stevens-Johnson Syndrome (SJS) Immune Suppression Bone Marrow Suppression Lymphadenopathy/Fever Possible Disease Associations Multiple Sclerosis Chronic Fatigue Syndrome Epilepsy Mesial/Temporal Lobe Epilepsy Status Epilepticus Colitis/Diarrhea Endocrine D...
Read more

A satirical story about in which AIDS activists get involved in promoting and defending science that turns out to be totally wrong and backfires on them

-
Fun from Perplexity Write a satirical story about in which AIDS activists get involved in promoting and defending science that turns out to be totally wrong and backfires on them Based on the research I've conducted, I now have enough information to write a satirical story about AIDS activists getting involved in promoting and defending flawed science. I'll create a fictional story that draws inspiration from the real history of AIDS activism, medical reversals, and scientific controversies to craft a satirical narrative that explores the themes requested. The Experts Dr. Marcus Sterling adjusted his wire-rimmed glasses and surveyed the packed auditorium with satisfaction. The banner hanging behind him read "Coalition for Revolutionary AIDS Research" in bold, rainbow letters. After eighteen months of relentless advocacy, CRAR had finally achieved what many thought impossible: they had convinced the medical establishment to embrace the groundbreaking "Cellular Har...
Read more

African Swine Fever and Kaposi's Sarcoma

-
 From Perplexity A.I. Make the case that the case that internal variable lesions in pigs with African Swine Fever are similar to the variable internal lesions of Kaposi's Sarcoma. African Swine Fever clinical presentation in the field ... Pathological Characteristics of Domestic Pigs Orally ... Full article: Pathogenicity and virulence of African swine ... Manual on meat inspection for developing countries Similarities Between Internal Variable Lesions in African Swine Fever (ASF) and Kaposi's Sarcoma Overview Both African Swine Fever (ASF) in pigs and Kaposi's Sarcoma (KS) in humans are characterized by lesions with marked variability in their internal distribution, severity, and appearance. Comparing the pathology of these diseases illuminates fundamental similarities in the variable and multi-organ nature of their internal lesions. 1. Lesion Distribution and Variability African Swine Fever: Lesions are highly variable depending on the virulence of the ASF virus and the d...
Read more

Perplexity looks at a challenging paradigm shift for AIDS and K.S.

-
  From Perplexity A.I . Make the case that the scientists who did autopsies on the first AIDS patients and found internal Kaposi's Sarcoma in all of them regardless of risk group, may have found out something that could one day change the nosology and causation theory of AIDS if scientists want to go back to the nosological (and epidemiological) drawing board and rethink the AIDS paradigm. Rethinking AIDS Nosology: The Implications of Early Autopsy Findings Introduction The initial autopsy studies on AIDS patients in the early 1980s, notably those identifying internal Kaposi's Sarcoma (KS) across various risk groups, presented findings that may still have profound implications for our understanding of AIDS. These data, often overshadowed by the viral causation narrative, could challenge and potentially expand the current nosological and etiological frameworks for AIDS if revisited with modern scientific approaches. The Significance of Early Autopsy Findings Internal Kaposi'...
Read more

What warnings would Eric Hoffer give about the fanaticism of the AIDS activists like Act Up?

-
  From Perplexity What warnings would Eric Hoffer give about the fanaticism of the AIDS activists like Act Up? Eric Hoffer’s Warnings on Fanaticism and Their Relevance to ACT UP Eric Hoffer, the influential author of The True Believer, deeply analyzed the psychology and dangers of fanaticism present in all types of mass movements. While he did not specifically address AIDS activism or the group ACT UP—whose activism began long after his most influential work—his general critiques provide insight into how he might have assessed the risks associated with highly zealous activism, even for just causes. Key Warnings Hoffer Would Likely Apply Motivation Rooted in Insecurity Hoffer asserted that the core of fanaticism is a deep sense of personal incompleteness and insecurity, which leads individuals to seek belonging and self-worth through passionate commitment to a cause, sometimes regardless of its particular content or justice. He argued, “The fanatic is perpetually incomplete and inse...
Read more

Popular Post in the Last 30 Days

-
Transplant Complications Bone marrow supression Colitis/diarrhea Delirium/CNS Dysfunction Encephalitis/Amnesia GVHD Hemophagocytic syndrome Hepatitis /Liver failure Pneumonitis Transplant Reactivation Overview Encephalitis Encephalitis / Meningitis Overview Encephalitis in the Immunocompromised Encephalitis in the Immunocompetent Rhomboencephalitis Limbic Encephalitis Encephalomyelitis Amnesia Rash & Roseola Seizures Febrile Seizures Status Epilepticus Cognitive Dysfunction Delirium Amnesia Hypersensitivity (DIHS/DRESS) Drug Induced Hypersensitivity Syndrome (DIHS) Drug Reaction with Eosinophilia & Systemic Symptoms (DRESS) Stevens-Johnson Syndrome (SJS) Immune Suppression Bone Marrow Suppression Lymphadenopathy/Fever Possible Disease Associations Multiple Sclerosis Chronic Fatigue Syndrome Epilepsy Mesial/Temporal Lobe Epilepsy Status Epilepticus Colitis/Diarrhea Endocrine D...
Read more

Consciousness of Guilt in Science and Medicine (From Perplexity A.I.)

-
  Develop the idea that there is something in science and medicine called "consciousness of fraud" (like consciousness of guilt) and list the telltale signs that a scientist is inadvertently showing it. The concept of "consciousness of fraud" in science and medicine parallels legal "consciousness of guilt," reflecting subtle behavioral and linguistic cues that betray a researcher's awareness of misconduct. These involuntary signs manifest through writing patterns, methodological choices, and professional behavior, often revealing attempts to conceal fabricated or manipulated data. Below are key telltale signs, synthesized from empirical studies and expert analyses of scientific fraud: 🔍 Linguistic and Writing Patterns Obfuscation in Language: Fraudulent papers use significantly more jargon, abstract terms, and complex phrasing to obscure methods or results. This "linguistic masking" aims to deter scrutiny, with fraudulent texts containing ~1...
Read more

We asked Perplexity A.I. to make the argument that Castleman's Disease undermines the nosology, epidemiology, and virology of AIDS.

-
 From Perplexity A.I. Make the argument that Castleman's Disease undermines the nosology, epidemiology, and virology of AIDS. Castleman disease, particularly its HIV-associated multicentric form (HIV-MCD), challenges core paradigms in AIDS medicine across nosology, epidemiology, and virology. Below is a detailed analysis of how this rare lymphoproliferative disorder complicates established frameworks. 🧬 Nosological Challenges HIV-MCD disrupts traditional AIDS classification by: Blurring diagnostic boundaries: It exhibits inflammatory symptoms (e.g., fever, cytopenia) and histopathology (plasmablastic proliferation) that overlap with—but are distinct from—classic AIDS-defining conditions like lymphoma or opportunistic infections. Dual-pathogen dynamics: Diagnosis requires confirming HHV-8 co-infection, positioning it as a viral co-pathogenesis rather than a direct HIV complication. This contrasts with AIDS nosology, which typically centers on HIV as the primary etiological agent. U...
Read more

If one studies all the medical literature on Chronic Fatigue Syndrome and AIDS, what viruses, infections, and pathological findings do they have in common? (From Perplexity)

-
 From Perplexity A.I. If one studies all the medical literature on Chronic Fatigue Syndrome and AIDS, what viruses, infections, and pathological findings do they have in common? If one studies all the medical literature on Chronic Fatigue Syndrome and AIDS, what viruses, infections, and pathological findings do they have in common? When reviewing the medical literature on  Chronic Fatigue Syndrome (CFS, also known as Myalgic Encephalomyelitis/ME)  and  AIDS  (Acquired Immunodeficiency Syndrome), several  viruses, infections, and pathological findings  are noted to overlap, though the diseases have distinct etiologies and clinical courses. Viruses and Infections in Common Herpesviruses:  Both conditions are associated with increased prevalence or reactivation of herpesviruses, notably  Cytomegalovirus (CMV)  and  Herpes Simplex Virus (HSV) . In AIDS, CMV is a common opportunistic infection, while in CFS, studies have found higher odd...
Read more

If the nosological definition of AIDS is reset to include all illnesses with serious inflammation regardless of HIV positivity or status, what illnesses could be included in the nosology of AIDS?

-
From Perplexity A.I. If the nosological definition of AIDS is reset to include all illnesses with serious inflammation regardless of HIV positivity or status, what illnesses could be included in the nosology of AIDS? If the nosological definition of AIDS were changed to include all illnesses with serious inflammation regardless of HIV positivity or status, the category would expand dramatically beyond its current, precise meaning. AIDS is currently defined by the presence of HIV infection leading to profound immunodeficiency and a specific set of opportunistic infections and cancers. Chronic inflammation is a hallmark of untreated HIV/AIDS, but it is not unique to it. If “AIDS” were redefined as any illness with serious inflammation, the following types of illnesses could be included: Autoimmune diseases: These are characterized by chronic, often severe inflammation due to the body’s immune system attacking its own tissues. Examples include: Rheumatoid arthritis Systemic lupus erythema...
Read more

Popular Posts from the Last Year

Oral Kaposi's Sarcoma looks like the Crimson Crescents in Chronic Fatigue Syndrome patients.

-
Image
This is what oral Kaposi's Sarcoma looks like. Source:  https://doctorspiller.com/kaposis-sarcoma/ Compare it to these crimson crescent lesions in the mouths of Chronic Fatigue Syndrome patients. "Burke A. Cunha, MD, discovered what he called crimson crescents in the mouths of 80% of his CFS patients. After the word got out, Cunha received calls from other parts of the country. Physicians began telling him that they also were finding the crimson crescents in their patients once they looked for them." https://www.prohealth.com/library/crimson-crescents-facilitate-chronic-fatigue-syndrome-cfs-diagnosis-11266 Chronic Fatigue Syndrome patients may have undiagnosed internal Kaposi's Sarcoma. Susan Levin found HHV-8, the Kaposi's Sarcoma virus, in half of CFS patients she looked at. Prevalence in the Cerebrospinal Fluid of the Following Infectious Agents in a Cohort of 12 CFS Subjects Susan Levine Published online: 04 Dec 2011 ABSTR...
Read more

Dr. Bhupesh Prusty and Professor Thomas Rudel discuss their HHV-6 research

-
Image
https://hhv-6foundation.org/cihhv-6/the-activation-of-cihhv-6-by-telomeric-circle-formation-qa-with-dr-bhupesh-prusty Tweet If you have Amazon Prime or Kindle Unlimited, you can immediately begin reading The Chronic Fatigue Syndrome Epidemic Cover-up and you will soon understand why the facts about the Chronic Fatigue Syndrome epidemic have been hidden from the public for almost four decades. Click here to begin reading Or purchase a print copy for only $20 shipped by Amazon Prime  If you want to know the truth about the Chronic Fatigue Syndrome epidemic, you need to discover the reporting of Neenyah Ostrom. For a decade, starting in 1988, Ostrom reported on Chronic Fatigue Syndrome for a newspaper called New York Native . What her reporting uncovered about the true nature of the Chronic Fatigue Syndrome epidemic will shock you.                                 ...
Read more

Dr. Rebecca Culshaw Smith's book is discussed on Twitter

-
  #AIDS #HIV #Truvada #TruvadaVictims #ClassAction An eye-opening, heart-breaking investigation. Dr. Rebecca Culshaw Smith's groundbreaking book exposes the tragic reality of 26,000 plaintiffs suing Gilead over the toxic side effects of HIV drug Truvada. https://t.co/PHVoKrafcU pic.twitter.com/hbh3mN4tdI — MyBookLists (@mybooklists) September 12, 2024
Read more

Ablashi discusses HHV-6, AIDS, Alzheimer's, and Chronic Fatigue Syndrome

-
Image
"HHV-6 is actually likely to reduce HIV patient survival by accelerating the depletion of CD4 and CD8 T cells. HHV-6A was shown to accelerate AIDS progression in macaques.  Macaques co-infected with simian HIV and HHV-6A died quickly and showed a dramatic depletion in both CD4+ and CD8+ T cells, whereas those infected with only simian HIV never progressed to full blown AIDS."  "We believe that infections are the most logical explanation for the inflammation neurodegeneration associated with Alzheimer’s , but don’t believe that there is a single pathogen responsible. HHV-6A and HHV-7 were identified as likely culprits in 2018 paper , using RNAseq analysis by Readhead and team. Two subsequent studies did not find an increase in HHV-6/7 using the same data, but at the same time did not find a significant presence of ANY herpesviruses in the brain, which we know is not the case. Dozens of careful studies have identified a high prevalence of low-level HHV-6 and HSV1 DN...
Read more

Is African Swine Fever a threat to human health in Congo?

-
Image
https://pmc.ncbi.nlm.nih.gov/articles/PMC7045278/ Our prior reporting on African Swine Fever ASF contaminated meat not entirely safe Besides, ASF-contaminated food could not be entirely safe for humans. “According to the latest research, though the virus is not dangerous to humans, there are documented reactions [of human bodies to ASF] in the form of production of antibodies against it. This indicates an ASF attempt to infect the body and the possibility of a serious weakening of the immune system,” Pavlov said. From 2018 ASF Russia: consumers want liability for sellers of contaminated meat (pigprogress.net) African Swine Fever is a big story already because, when and if it spreads to all of Western Europe and China, it will cause the collapse of a major portion of the agricultural export economies of the affected countries. We're talking about many billions of dollars of losses. And the problem is not temporary because those countries will be suspected of harboring the disease ...
Read more

All Time Most Popular Posts

Dr. Bhupesh Prusty and Professor Thomas Rudel discuss their HHV-6 research

-
Image
https://hhv-6foundation.org/cihhv-6/the-activation-of-cihhv-6-by-telomeric-circle-formation-qa-with-dr-bhupesh-prusty Tweet If you have Amazon Prime or Kindle Unlimited, you can immediately begin reading The Chronic Fatigue Syndrome Epidemic Cover-up and you will soon understand why the facts about the Chronic Fatigue Syndrome epidemic have been hidden from the public for almost four decades. Click here to begin reading Or purchase a print copy for only $20 shipped by Amazon Prime  If you want to know the truth about the Chronic Fatigue Syndrome epidemic, you need to discover the reporting of Neenyah Ostrom. For a decade, starting in 1988, Ostrom reported on Chronic Fatigue Syndrome for a newspaper called New York Native . What her reporting uncovered about the true nature of the Chronic Fatigue Syndrome epidemic will shock you.                                 ...
Read more

Anthony Fauci was part of the gang that silenced and destroyed Judy Mikovits.

-
Image
Read the interview in which Judy Mikovits called Chronic Fatigue Syndrome "Non-HIV AIDS." https://www.prohealth.com/library/plague-an-interview-with-judy-mikovits-32911   If you have Amazon Prime or Kindle Unlimited you can immediately begin reading this book. If you have Amazon Prime or Kindle Unlimited, you can immediately begin reading The Chronic Fatigue Syndrome Epidemic Cover-up and you will soon understand why the facts about the Chronic Fatigue Syndrome epidemic have been hidden from the public for almost four decades. Click here to begin reading Or purchase a print copy for only $20 shipped by Amazon Prime  This is the book causing heated debates about Chronic Fatigue Syndrome and HHV-6, "The Fifty Shades of AIDS Virus," in laboratories, doctor's offices, and homes all over the world.                                         ...
Read more

Was Judy Mikovits destroyed because her XMRV work would have ultimately shown HIV is a total fraud?

-
Image
How much HIV research can be replicated? Is the whole field of AIDS build on HIV pseudoscience that cannot be replicated? We need an HIV replication movement that demands it all be replicated. We need to know if HIV is a solid as XMRV. How has HIV helped hide the epidemic of Chronic Fatigue Syndrome which has been called "Non-HIV AIDS"? Read this book if you want to know the whole story. Available now on Amazon here .
Read more

Is Chronic Fatigue Syndrome the other AIDS epidemic in the gay community?

-
Image
https://www.gscene.com/news/new-doctors-guidelines-for-severe-me/ On April 16, 1996, Congressman Jerrold Nadler spoke on the floor of Congress about his request for a General Accounting investigation into how the CDC had handled the Chronic Fatigue Syndrome epidemic. Nadler did that at the urging of Charles Ortleb, the publisher and the New York Native and his reporter Neenyah Ostrom. Ortleb and Ostrom had made the case to Nadler that Chronic Fatigue Syndrome and the virus it had been linked to, HHV-6, were serious public health issues.                                                 In an interview in New York Native with Neenyah Ostrom,Congressman Nadler said, "Congress can mandate research into CFS as a viral disease. Maybe it will turn out that HHV-6A is the cause of CFS; maybe it will turn out that other viruses are involved. But Con...
Read more