Is Kaposi's Sarcoma responsible for the digestive disorders in Chronic Fatigue Syndrome?

Kaposi Sarcoma Involving the Gastrointestinal Tract

Although gastrointestinal Kaposi sarcoma is usually asymptomatic, hemorrhages from the oral cavity, esophagus, stomach, and large bowel have been reported in this disease., Some patients present with abdominal pain, weight loss, nausea, vomiting, malabsorption, or diarrhea.Further complications of gastrointestinal Kaposi sarcoma can be perforation or obstruction of the bowel.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2933764/



This is what oral Kaposi's Sarcoma looks like.




Source: https://doctorspiller.com/kaposis-sarcoma/

Compare it to these crimson crescent lesions in the mouths of Chronic Fatigue Syndrome patients.



"Burke A. Cunha, MD, discovered what he called crimson crescents in the mouths of 80% of his CFS patients. After the word got out, Cunha received calls from other parts of the country. Physicians began telling him that they also were finding the crimson crescents in their patients once they looked for them."

https://www.prohealth.com/library/crimson-crescents-facilitate-chronic-fatigue-syndrome-cfs-diagnosis-11266




Chronic Fatigue Syndrome patients may have undiagnosed internal Kaposi's Sarcoma. Susan Levine found HHV-8, the Kaposi's Sarcoma virus, in half of CFS patients she looked at.

Prevalence in the Cerebrospinal Fluid of the Following Infectious Agents in a Cohort of 12 CFS Subjects
Susan Levine

Published online: 04 Dec 2011


Over the last decade a wide variety of infectious agents has been associated with the chronic fatigue syndrome (CFS) as potential etiologies for this disorder by researchers from all over the world. Many of these agents are neurotrophic and have been linked previously to other diseases involving the central nervous system (CNS). Human herpes virus-6 (HHV-6), especially the B variant, has been found in autopsy specimens of patients who suffered from multiple sclerosis. Because patients with CFS manifest a wide range of symptoms involving the CNS as shown by abnormalities on brain MRIs, SPECT scans of the brain and results of tilt table testing we sought to determine the prevalence of HHV-6, HHV-8, Epstein-Barr virus (EBV), cytomegalovirus (CMV), Mycoplasma species, Chlamydia species, and Coxsackie virus in the spinal fluid of a group of 12 patients with CFS. Although we intended to search mainly for evidence of actively replicating HHV-6, a virus that has been associated by several researchers with this disorder, we found evidence of HHV-8, Chlamydia species, CMV and Coxsackie virus in 6/12 samples. Attempts were made to correlate the clinical presentations of each of these patients, especially the neurological exams and results of objective testing of the CNS, with the particular infectious agent isolated. It was also surprising to obtain such a relatively high yield of infectious agents on cell free specimens of spinal fluid that had not been centrifuged. Future research in spinal fluid analysis, in addition to testing tissue samples by polymerase chain reaction (PCR) and other direct viral isolation techniques will be important in characterizing subpopulations of CFS patients, especially those with involvement of the CNS.

https://www.tandfonline.com/doi/abs/10.1300/J092v09n01_05






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