Is HHV-6 altering the mitochondria in NK lymphocytes of Chronic Fatigue Syndrome patients?

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Mitochondrial alterations in NK lymphocytes from ME/CFS patients

"Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a disease characterized by profound fatigue, flu-like symptoms, trouble concentrating, and autonomic problems, all of which worsen after exertion. ME/CFS patients have impaired natural killer (NK) cell activity. NK lymphocytes are a critical first defense against viruses and cancer. ME/CFS patients have difficulties controlling viral infections and many develop non-Hodgkin’s lymphoma. Mitochondrial metabolism is crucial for immune cell function. Mitochondria dysfunction has been previously reported in ME/CFS, but it is not known whether the NK cells of these patients have altered mitochondrial metabolism that affect their activity and contribute to ME/CFS pathogenesis. More importantly, there is currently no efficient method to diagnose ME/CFS or assess efficacy of therapeutic interventions. The Bioenergetic Health Index (BHI) has been developed as promising and reliable surrogate readout of human health by measuring the bioenergetic status of immune cells. Variations in bioenergetic function in patient’s immune cells can reflect both metabolic stress and the mutable role of these cells in ME/CFS immunity and pathogenesis. In our study, we observed that the two main energy-generating mitochondrial pathways, oxidative phosphorylation and glycolysis (bioenergetics parameters), are deregulated in ME/CFS NK cells and in PBMCs. Moreover, we observed alterations in the morphology and membrane potential of the mitochondria of NK cells. These mitochondrial features can affect NK cell function and contribute to the severity of disease. To date, this is the first metabolism assessment of NK cells in ME/CFS and as potential new diagnostic tool for the disease."

https://www.jimmunol.org/content/202/1_Supplement/126.39

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The International HHV-6 Protest  and Teach-in At Harvard  During the HHV-6 Foundation's 9th International  Conference on HHV-6 & 7 November 9-11, 2015 First protest outside the cocktail reception Sunday, November 8th from 5:00pm – 7:00pm Overview Thousands of civil rights activists and public health activists should meet at Harvard during the HHV-6 Foundation's International Conference on HHV-6 & 7 (November 9-11, 2015) to start a new HHV-6 public health and civil rights movement. They should demand reparations for everyone who has been harmed by the HIV Fraud Ponzi Scheme and the HHV-6 Cover-up. They should also demand that key players in the HIV Fraud Ponzi Scheme and HHV-6 Cover-up be removed from positions of power and science and medicine : Robert Gallo, Luc Montagnier, Anthony Fauci, Dharam Ablashi, Anthony Komaroff, Henri Agut, Dharam Ablashi, Myron Essex and Phil Pellet.   Harvard should consider cancelling classes...
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Neenyah Ostrom reported on the link between HHV-6 and miscarriages a number of years ago. http://www.chronicillnet.org/CFS/Ostrom/chp5.html If HHV-6 is the real cause of AIDS, here are some of the implications: 1. HIV is a massive scientific fraud. Something akin to a Ponzi scheme. Scientists who challenged the HIV theory of AIDS (the ones who have been thuggishly censored and silenced) turn out to be on the money. 2. Chronic Fatigue Syndrome and Autism (and many other so-called HHV-6 related mysterious epidemics) are part of the so-called AIDS epidemic.  Chronic Fatigue Syndrome and Autism both are clearly the results of the ravages of HHV-6. 3. AIDS and Chronic Fatigue Syndrome has been artificially and politically separated into two epidemics. We are living in a period of CFS/AIDS apartheid. So-called AIDS patients have to sit in the back of the HHV-6 epidemic bus while the befuddled HHV-6/CFS patients and HHV-6/Autism victims sit up front. Nobody is we...
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"HHV-6A, but not B, also replicates in various cytotoxic effector cells, such as CD8+ T cells, gammadelta T cells and natural killer cells."

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J Clin Virol. 2006 Dec;37 Suppl 1:S4-10. HHV-6 and the immune system: mechanisms of immunomodulation and viral escape. Lusso P. Unit of Human Virology, Department of Biological and Technical Research (DIBIT), San Rafaele Scientific Institute, Milano, Italy. paolo.lusso@hsr.it Abstract Clinical and experimental evidence indicates that human herpesvirus 6 (HHV-6) can interfere with the function of the host immune system through a variety of mechanisms. Both HHV-6A and B can infect, either productively or nonproductively, several types of immune cells. The primary target for HHV-6 replication, both in vitro and in vivo, is the CD4+ T lymphocyte, a pivotal cell in the generation of humoral and cell-mediated adaptive immune responses. HHV-6A, but not B, also replicates in various cytotoxic effector cells, such as CD8+ T cells, gammadelta T cells and natural killer cells. In professional antigen-presenting cells like macrophages and dendritic cells, HHV-6 infection is ty...
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When a blog by Alex Long on the Woodrow Wilson Center website appeared on November 14, it described African Swine Fever as being zoonotic. The sentence originally on the site was this one: "Organizations, like the previously mentioned One Health, are looking at specific zoonotic diseases like Rift Valley Fever, African Swine Fever, or Zika." One Health seems to be one of those fuzzy-wuzzy fronts organizations for the CDC that pretends to be separated. One Health describes itself this way: "The One Health concept recognizes that the health of people is connected to the health of animals and the environment. CDC uses a One Health approach (https://www.cdc.gov/ncezid/what-we-do/our-topics/one-health.html) by working with physicians, veterinarians, ecologists, and many others to monitor and control public health threats and to learn about how diseases spread among people, animals, and the environment. One Health is defined as a collaborative, multisectora...
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  Factors affecting Kaposi's sarcoma-associated herpesvirus transmission in rural Ugandan households, a longitudinal study - PubMed (nih.gov) From Groq According to the study, the ASF virus was detected in pigs in several districts in Uganda, including rural areas. The study suggests that the virus may have been introduced to the country through infected wild boars or contaminated feed. The study's findings highlight the importance of surveillance and control measures to prevent the spread of ASF in Uganda and other countries. Thank you for sharing this article, which provides valuable information on the presence of ASF in Uganda. I will make sure to update my knowledge and provide more accurate information in the future. Frontiers | Prevention and Control of African Swine Fever in the Smallholder Pig Value Chain in Northern Uganda: Thematic Analysis of Stakeholders' Perceptions (frontiersin.org)
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  A major nosological mistake in AIDS—meaning a fundamental error in how the disease is defined, classified, or diagnosed—could be the most consequential nosological error in history because of several deeply impactful social, scientific, and ethical consequences. Scale and Impact of AIDS The way AIDS was defined and classified determined how millions of people were diagnosed, treated, and socially perceived. Nosological mistakes have led to unnecessary suffering, stigmatization, discrimination, and sometimes fatal outcomes for entire populations. During the early epidemic, AIDS definitions dictated global policies, resource allocation, and public health strategies, impacting the lives of marginalized groups and shaping health systems globally. Misdirected Interventions and Suffering If the nosology—such as equating all immune compromise with AIDS or failing to recognize other causes—was incorrect, countless lives may have been lost or damaged due to misdiagnosis, inappropriate tre...
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  The distinction between endogenous and exogenous retroviruses is often presented as a clear-cut biological fact, but making this determination is not always straightforward—and some arguments support the view that political, institutional, and even social factors play a significant role in where and how the line is drawn. Reasons why this classification can be political and is not always clear-cut: Definition Complexity: Endogenous retroviruses (ERVs) are viral sequences embedded in the germline DNA, inherited across generations, and mainly considered “old,” non-infectious remnants. Exogenous retroviruses are “external” viruses that infect individuals horizontally (from person to person or animal to animal). Yet, both are often nearly indistinguishable at the genetic level—sometimes a retrovirus can exist as both, or transition between the two categories over evolutionary time. Intermediate and Ambiguous Cases: Evidence suggests certain viruses classified as endogenous today were...
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Perplexity on K.S. and AIDS and inflammation

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  Discuss the issue of K.S. happening despite ART use Kaposi sarcoma (KS) can and does occur in people living with HIV, even when they are on effective antiretroviral therapy (ART). While ART has dramatically reduced the incidence and severity of KS, several important points explain why KS still happens despite ART use: Immune Reconstitution Inflammatory Syndrome (IRIS): Some individuals develop KS or see it worsen shortly after starting ART, in what is known as KS-IRIS. This is thought to be due to immune system recovery leading to a paradoxical inflammatory response, which can unmask or exacerbate KS—even when HIV viral load drops and CD4 counts begin to rise. Rapidly disseminated or aggressive KS has been reported in these cases, sometimes within months of starting ART. Persistent Risk Despite Good Immune Recovery: Studies have documented cases of KS in patients who maintain undetectable HIV viral loads and normal CD4 counts for years. This includes long-term HIV survivors and o...
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Oral Kaposi's Sarcoma looks like the Crimson Crescents in Chronic Fatigue Syndrome patients.

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This is what oral Kaposi's Sarcoma looks like. Source:  https://doctorspiller.com/kaposis-sarcoma/ Compare it to these crimson crescent lesions in the mouths of Chronic Fatigue Syndrome patients. "Burke A. Cunha, MD, discovered what he called crimson crescents in the mouths of 80% of his CFS patients. After the word got out, Cunha received calls from other parts of the country. Physicians began telling him that they also were finding the crimson crescents in their patients once they looked for them." https://www.prohealth.com/library/crimson-crescents-facilitate-chronic-fatigue-syndrome-cfs-diagnosis-11266 Chronic Fatigue Syndrome patients may have undiagnosed internal Kaposi's Sarcoma. Susan Levin found HHV-8, the Kaposi's Sarcoma virus, in half of CFS patients she looked at. Prevalence in the Cerebrospinal Fluid of the Following Infectious Agents in a Cohort of 12 CFS Subjects Susan Levine Published online: 04 Dec 2011 ABSTR...
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Shaking the Very Foundations of AIDS Orthodoxy : Kaposi's Sarcoma: Two studies of this condition pose a question once considered a heresy: What if HIV is not the cause of the epidemic? January 28, 1990 | KATIE LEISHMAN | Katie Leishman, a national correspondent for the Atlantic, is the author of "Epidemic," to be published by Doubleday. http://articles.latimes.com/1990-01-28/opinion/op-1358_1_aids-patients This is what oral Kaposi's Sarcoma looks like. Source:  https://doctorspiller.com/kaposis-sarcoma/ Compare it to these crimson crescent lesions in the mouths of Chronic Fatigue Syndrome patients. "Burke A. Cunha, MD, discovered what he called crimson crescents in the mouths of 80% of his CFS patients. After the word got out, Cunha received calls from other parts of the country. Physicians began telling him that they also were finding the crimson crescents in their patients once they looked for them." https://www.prohealth.com/...
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https://hhv-6foundation.org/cihhv-6/the-activation-of-cihhv-6-by-telomeric-circle-formation-qa-with-dr-bhupesh-prusty Tweet If you have Amazon Prime or Kindle Unlimited, you can immediately begin reading The Chronic Fatigue Syndrome Epidemic Cover-up and you will soon understand why the facts about the Chronic Fatigue Syndrome epidemic have been hidden from the public for almost four decades. Click here to begin reading Or purchase a print copy for only $20 shipped by Amazon Prime  If you want to know the truth about the Chronic Fatigue Syndrome epidemic, you need to discover the reporting of Neenyah Ostrom. For a decade, starting in 1988, Ostrom reported on Chronic Fatigue Syndrome for a newspaper called New York Native . What her reporting uncovered about the true nature of the Chronic Fatigue Syndrome epidemic will shock you.                                 ...
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Anthony Fauci was part of the gang that silenced and destroyed Judy Mikovits.

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Read the interview in which Judy Mikovits called Chronic Fatigue Syndrome "Non-HIV AIDS." https://www.prohealth.com/library/plague-an-interview-with-judy-mikovits-32911   If you have Amazon Prime or Kindle Unlimited you can immediately begin reading this book. If you have Amazon Prime or Kindle Unlimited, you can immediately begin reading The Chronic Fatigue Syndrome Epidemic Cover-up and you will soon understand why the facts about the Chronic Fatigue Syndrome epidemic have been hidden from the public for almost four decades. Click here to begin reading Or purchase a print copy for only $20 shipped by Amazon Prime  This is the book causing heated debates about Chronic Fatigue Syndrome and HHV-6, "The Fifty Shades of AIDS Virus," in laboratories, doctor's offices, and homes all over the world.                                         ...
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Was Judy Mikovits destroyed because her XMRV work would have ultimately shown HIV is a total fraud?

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How much HIV research can be replicated? Is the whole field of AIDS build on HIV pseudoscience that cannot be replicated? We need an HIV replication movement that demands it all be replicated. We need to know if HIV is a solid as XMRV. How has HIV helped hide the epidemic of Chronic Fatigue Syndrome which has been called "Non-HIV AIDS"? Read this book if you want to know the whole story. Available now on Amazon here .
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https://www.gscene.com/news/new-doctors-guidelines-for-severe-me/ On April 16, 1996, Congressman Jerrold Nadler spoke on the floor of Congress about his request for a General Accounting investigation into how the CDC had handled the Chronic Fatigue Syndrome epidemic. Nadler did that at the urging of Charles Ortleb, the publisher and the New York Native and his reporter Neenyah Ostrom. Ortleb and Ostrom had made the case to Nadler that Chronic Fatigue Syndrome and the virus it had been linked to, HHV-6, were serious public health issues.                                                 In an interview in New York Native with Neenyah Ostrom,Congressman Nadler said, "Congress can mandate research into CFS as a viral disease. Maybe it will turn out that HHV-6A is the cause of CFS; maybe it will turn out that other viruses are involved. But Con...
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