More evidence linking Chronic Fatigue Syndrome to the AIDS epidemic

-

Redox Imbalance: A Core Feature of ME/CFS and Acute COVID-19


 Redox Imbalance: A Core Feature of ME/CFS and Acute COVID-19 – CENTER FOR SOLUTIONS FOR ME/CFS (cfsformecfs.org)

The Role of Oxidative Imbalance in Progression to AIDS: Effect of the Thiol Supplier N-Acetylcysteine

    Published Online:15 Mar 2009https://doi.org/10.1089/aid.1998.14.1589

    Abstract

    In this study we investigate the redox profile of HIV+ patients at different stages of disease with regard to immunological parameters, i.e., the number of circulating CD4+ and CD8+ lymphocytes. For this purpose, peripheral blood mononuclear cells (PBMCs) obtained from healthy donors, HIV+ patients in the asymptomatic phase, long-term nonProgressors (LTNPs), and AIDS patients have been considered. Cells have been exposed in vitro to the prooxidizing agent menadione, which is able to induce superoxide anion formation, and the susceptibility of the cells to the induced oxidative stress was estimated. Moreover, the possibility that the susceptibility of the cells to oxidative stress might be reduced by preexposing them to the antioxidizing agent N-acetylcysteine (NAC) has also been analyzed. The results obtained can be summarized as follows: (1) treatment with the prooxidant agent is capable of inducing massive morphological alterations in PBMCs. In particular, a significant correlation was found between the decrease in number of CD4+ lymphocytes in patients at different stages of disease and the susceptibility of their PBMCs to oxidative stress; (2) preincubation with NAC was able to preserve partially the ultrastructural characteristics of PBMCs isolated from HIV+ patients. In particular, a direct relationship was found between the efficacy of NAC protection and CD4 counts; (3) evaluation of the plasma index of peroxidation and the number of circulating CD4 lymphocytes indicates the existence of a positive correlation between "systemic" oxidative imbalance and stage of the disease; and (4) cells from LTNPs display either oxidative susceptibility or oxidative markers similar to those of healthy donor cells. Our study suggests that the redox profile of patients may be considered a predictive marker of AIDS progression and that the acute infection and the asymptomatic phase of the disease may represent a useful period in which the combined use of antiretroviral and antioxidant drugs may be beneficial.


    The Chronic Fatigue Syndrome Awareness Anthem on Spotify

    Popular Posts in the Last 7 Days

    Oral Kaposi's Sarcoma looks like the Crimson Crescents in Chronic Fatigue Syndrome patients.

    -
    Image
    This is what oral Kaposi's Sarcoma looks like. Source:  https://doctorspiller.com/kaposis-sarcoma/ Compare it to these crimson crescent lesions in the mouths of Chronic Fatigue Syndrome patients. "Burke A. Cunha, MD, discovered what he called crimson crescents in the mouths of 80% of his CFS patients. After the word got out, Cunha received calls from other parts of the country. Physicians began telling him that they also were finding the crimson crescents in their patients once they looked for them." https://www.prohealth.com/library/crimson-crescents-facilitate-chronic-fatigue-syndrome-cfs-diagnosis-11266 Chronic Fatigue Syndrome patients may have undiagnosed internal Kaposi's Sarcoma. Susan Levin found HHV-8, the Kaposi's Sarcoma virus, in half of CFS patients she looked at. Prevalence in the Cerebrospinal Fluid of the Following Infectious Agents in a Cohort of 12 CFS Subjects Susan Levine Published online: 04 Dec 2011 ABSTR...
    Read more

    Military being enlisted to fight African Swine Fever in the Dominican Republic

    -
      Dominican Republic restricts pig shipments, enlists military to fight African swine fever | Reuters In August, 1986, John Beldekas was invited to go to the NCI and present his findings on the link between ASFV [African Swine Fever virus] and AIDS, which he did. Beldekas gave samples of all his lab work to Gallo. Later, the government asked Beldekas to turn over all his reagents and lab work to the government, which he did. Beldekas had found ASFV presence in nine of 21 AIDS patients using two standard procedures. At the meeting, Gallo was reported saying: “we know it is not ASFV.” How could Gallo know this as he hadn’t done any of his own tests to look for ASFV? Two months later, Gallo published an article in Science (Oct 31, 1986) that he discovered a new possible co-factor in AIDS, a virus he called Human B Cell Lymphotropic Virus which he named HBLV. Like ASFV, HBLV infected B cells and also lived in macrophages. Did Gallo steal Beldekas’s ASF virus he found in AIDS patients a...
    Read more

    Gallo's early statements about HHV-6

    -
    Gallo's early statements about HHV-6 are discussed in this excerpt from Nick Regush's The Virus Within (page. 13).   When NCI laboratory research revealed the extent of HHV-6's destructive power, Robert Gallo began to speak out about the implications. On May 10, 1988, at the annual meeting of the American Society of Microbiology in Miami, he told an audience that HHV-6 had been found along with HIV in T-4 cells, and speculated that the new herpes virus could be a "co-factor" in AIDS. One month later, at an international AIDS conference in Stockholm, he explained that HHV-6 killed T-4 cells in the test tube more effectively than did HIV, and said the new herpes virus could cause massive cell death. Gallo reasoned that HHV-6 infection might help speed up the HIV-led breakdown of the immune system in AIDS, although he cautioned that NCI research on HHV-6 was still preliminary. The Virus Within: A Coming Epidemic: Regush, Nicholas: 9780525945345: Amazon.com: Books
    Read more

    Anna Fogdell-Hahne is the HHV-6 Scientist of the year

    -
    Image
    Anna Fogdell Hahn, researcher at the Department of Clinical Neuroscience at Karolinska Institutet in Sweden. MS linked to variant of HHV-6 (the CFS/AIDS virus) through new method Researchers at Karolinska Institutet have developed a new method to separate between two different types of a common herpes virus (HHV-6) that has been linked to multiple sclerosis. By analyzing antibodies in the blood against the most divergent proteins of herpesvirus 6A and 6B, the researchers were able to show that MS-patients carry the herpesvirus 6A to a greater extent than healthy individuals. The findings, published in Frontiers in Immunology, point to a role for HHV-6A in the development of MS. 
    Read more

    Bhupesh Prusty, Konnie Knox, and Brigitte Huber have done the most important research on HHV-6. Why is Huber's retroviral finding about HHV-6 being ignored????

    -
    Image
      HHV-6A infection induces expression of HERV-K18-encoded superantigen Albert K. Taia, Janos Lukab, Dharam Ablashi, Brigitte T. Huber published online 08 June 2009. Abstract Background The human endogenous retrovirus K-18 (HERV-K18) encodes a superantigen that causes deregulation of the immune system. This provirus is transcriptionally silent, but can be induced by Epstein–Barr virus (EBV) infection and IFN-α treatment. Objectives Since the herpesvirus EBV induces HERV-K18 expression in human B cells, it was of interest to determine if other herpesviruses would have similar HERV-K18 transactivation properties. Human herpesvirus (HHV)-6A, a neurotropic virus associated with multiple sclerosis, was a logical candidate for these studies. Study design HSB2 cells (HHV-6-negative control), HSB2-ML cells (containing latent HHV-6A genome) and HSB2/HHV-6A cells (HSB-2 cells productively infected with HHV-6A) were compared for their level of HERV-K18 transcription, using quantitative RT...
    Read more

    Karen Lambert’s Struggle with HIV-Negative AIDS (CFS)

    -
    Image
    https://www.facebook.com/GlobalPublicAlert/photos/a.596025227087646.1073741848.178630692160437/799951666695000 "I have Chronic Fatigue Immune Dysfunction Syndrome (CFS/CFIDS/ME) and HIV-NEGATIVE AIDS, idiopathic CD lymphocytopenia. With these two clinical diagnoses, I believe that makes me living proof that the AIDS-like CFS/ME is transmissible, something that the medical establishment seems unable to admit or to acknowledge. I also believe it makes me living proof that CFS and HIV-NEGATIVE AIDS are basically the same mysterious immune disorder."
    Read more

    Look at what Groq A.I. came up with for a plot for a novel that portrays HIV as a Ponzi scheme.

    -
     Can you write the plot for a novel in which HIV turns out to be a virtual Ponzi scheme concealing a much bigger epidemic of AIDS caused by a different virus and having multiple manifestations? Here's a potential plot for a novel: Title: The Shadow Virus Protagonist Dr. Sophia Patel, a brilliant and determined epidemiologist, has spent her entire career studying HIV. She's convinced that the virus is the root of the global AIDS epidemic, and she's dedicated her life to finding a cure. But when a mysterious new strain of HIV emerges, Sophia begins to suspect that something is off. As she delves deeper into the research, Sophia discovers that the new strain is unlike anything she's ever seen before. It's highly contagious, but it seems to be affecting people in unexpected ways. Some patients are experiencing severe neurological symptoms, while others are developing rare skin conditions. The more Sophia learns, the more she realizes that this new strain is not just a v...
    Read more

    Popular Post in the Last 30 Days

    Oral Kaposi's Sarcoma looks like the Crimson Crescents in Chronic Fatigue Syndrome patients.

    -
    Image
    This is what oral Kaposi's Sarcoma looks like. Source:  https://doctorspiller.com/kaposis-sarcoma/ Compare it to these crimson crescent lesions in the mouths of Chronic Fatigue Syndrome patients. "Burke A. Cunha, MD, discovered what he called crimson crescents in the mouths of 80% of his CFS patients. After the word got out, Cunha received calls from other parts of the country. Physicians began telling him that they also were finding the crimson crescents in their patients once they looked for them." https://www.prohealth.com/library/crimson-crescents-facilitate-chronic-fatigue-syndrome-cfs-diagnosis-11266 Chronic Fatigue Syndrome patients may have undiagnosed internal Kaposi's Sarcoma. Susan Levin found HHV-8, the Kaposi's Sarcoma virus, in half of CFS patients she looked at. Prevalence in the Cerebrospinal Fluid of the Following Infectious Agents in a Cohort of 12 CFS Subjects Susan Levine Published online: 04 Dec 2011 ABSTR...
    Read more

    Dr. Konstance Knox explains why HHV-6 may be the key to dealing with AIDS.

    -
      by Neenyah Ostrom New York Native , issue #678, April 15, 1996 Konstance Knox, Ph.D., is an HHV-6 researcher who has just published a study with extraordinary implications for AIDS research and treatment strategies. Along with colleague Donald R. Carrigan, Ph.D., Knox demonstrated that 100 percent of HIV-infected patients studied (ten out of ten) had active Human Herpes Virus 6 Variant A infections in their lymph nodes early in the course of their disease. Seventy-five percent of these patients, in fact, had CD4 cell counts higher than 200 (the cut-off for receiving a diagnosis of AIDS), up to as high a CD4 count as 700. This finding led Knox and Carrigan to conclude that "active HHV-6 infections appear relatively early in the course of HIV disease and in vitro studies suggest that the A variant of HHV-6 is capable of breaking HIV latency, with the potential for helping to catalyze the progression of HIV infection to AIDS." This new study, in other words, presents data furt...
    Read more

    Has Maureen Hanson found another opportunistic infection that links Chronic Fatigue Syndrome and AIDS?

    -
      The Enterovirus Theory of Disease Etiology in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Critical Review Adam J. O'Neal  and  Maureen R. Hanson * Abstract Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a complex, multi-system disease whose etiological basis has not been established. Enteroviruses (EVs) as a cause of ME/CFS have sometimes been proposed, as they are known agents of acute respiratory and gastrointestinal infections that may persist in secondary infection sites, including the central nervous system, muscle, and heart. To date, the body of research that has investigated enterovirus infections in relation to ME/CFS supports an increased prevalence of chronic or persistent enteroviral infections in ME/CFS patient cohorts than in healthy individuals. Nevertheless, inconsistent results have fueled a decline in related studies over the past two decades. This review covers the aspects of ME/CFS pathophysiology that are consistent with a ...
    Read more

    HHV-6: The 50 Shades of AIDS Virus

    -
    From the forthcoming book HHV-6: The fifty Shades of AIDS Virus which will be published in time for the International HHV-6 Protest in Berlin July 23-26. Does HHV-6 act like African Swine Fever virus? In many ways. Is HHV-6 a human form of African Swine Fever? It might as well be. Given that it was Robert Gallo's people who decided that HHV-6 is not ASFV, all bets are off. Is Robert Gallo a scientific crook? Big time. Read John Crewdson's Science Fictions if you want the whole story. What about the scientists who worked with him? They were all his enablers, so all of their work needs to be taken with a grain of salt. How come they never spoke out about him? He is the biggest thug in science. He is a combination of Nixon and Trump. Everyone was afraid of him. So Gallo's fingerprints are all over the HHV-6 epidemic and its cover-up? For sure. More to come tomorrow. For more than a decade my newspaper, New York Native , warned New Yor...
    Read more

    Has anyone suggested that African Swine Fever virus acts like a superantigen?

    -
     Has anyone suggested that African Swine Fever virus acts like a superantigen? From Perplexity A.I. Superantigenic Activity in African Swine Fever Virus: Current Evidence and... Could HHV-6 and HHV-8 also act like superantigens The available evidence does not strongly support HHV-6 or HHV-8 acting as classical superantigens, but both viruses exhibit immune-modulating properties that share some functional parallels with superantigen activity: HHV-6 Immune Interactions T Cell Activation: HHV-6 preferentially infects activated CD4+ T cells and can also infect CD8+ T cells (HHV-6A). It induces proinflammatory cytokines (IL-6, CCL-1, Rantes) in infected olfactory ensheathing cells and PBMCs, but this is mediated through direct infection rather than non-specific T cell receptor (TCR) cross-linking. Cross-reactive T cell epitopes (e.g., HHV-6 U24 vs. myelin basic protein) exist, but these involve antigen-specific recognition rather than broad TCR Vβ activation. Immunomodulation: CD46 bind...
    Read more

    Groq on miRNAs and retroviruses.

    -
     Are miRNAs ever confused with retroviruses? Yes, microRNAs (miRNAs) and retroviruses can be confused with each other due to some similarities in their structure and function. Here are a few reasons why: Both miRNAs and retroviruses are small RNA molecules: miRNAs are typically 18-25 nucleotides in length, while retroviruses can have varying lengths, but are often around 5-10 kilobases. However, some retroviruses, such as human T-cell leukemia virus type 1 (HTLV-1), have shorter RNA genomes that are similar in size to miRNAs. Both can integrate into host genomes: miRNAs can integrate into host genomes through a process called RNA-directed DNA methylation, while retroviruses can integrate their genomes into host DNA through a process called reverse transcription. Both can regulate gene expression: miRNAs regulate gene expression by binding to messenger RNA (mRNA) and preventing its translation, while retroviruses can regulate gene expression by inserting their genomes into host DNA ...
    Read more

    Popular Posts from the Last Year

    Oral Kaposi's Sarcoma looks like the Crimson Crescents in Chronic Fatigue Syndrome patients.

    -
    Image
    This is what oral Kaposi's Sarcoma looks like. Source:  https://doctorspiller.com/kaposis-sarcoma/ Compare it to these crimson crescent lesions in the mouths of Chronic Fatigue Syndrome patients. "Burke A. Cunha, MD, discovered what he called crimson crescents in the mouths of 80% of his CFS patients. After the word got out, Cunha received calls from other parts of the country. Physicians began telling him that they also were finding the crimson crescents in their patients once they looked for them." https://www.prohealth.com/library/crimson-crescents-facilitate-chronic-fatigue-syndrome-cfs-diagnosis-11266 Chronic Fatigue Syndrome patients may have undiagnosed internal Kaposi's Sarcoma. Susan Levin found HHV-8, the Kaposi's Sarcoma virus, in half of CFS patients she looked at. Prevalence in the Cerebrospinal Fluid of the Following Infectious Agents in a Cohort of 12 CFS Subjects Susan Levine Published online: 04 Dec 2011 ABSTR...
    Read more
    -
    Transplant Complications Bone marrow supression Colitis/diarrhea Delirium/CNS Dysfunction Encephalitis/Amnesia GVHD Hemophagocytic syndrome Hepatitis /Liver failure Pneumonitis Transplant Reactivation Overview Encephalitis Encephalitis / Meningitis Overview Encephalitis in the Immunocompromised Encephalitis in the Immunocompetent Rhomboencephalitis Limbic Encephalitis Encephalomyelitis Amnesia Rash & Roseola Seizures Febrile Seizures Status Epilepticus Cognitive Dysfunction Delirium Amnesia Hypersensitivity (DIHS/DRESS) Drug Induced Hypersensitivity Syndrome (DIHS) Drug Reaction with Eosinophilia & Systemic Symptoms (DRESS) Stevens-Johnson Syndrome (SJS) Immune Suppression Bone Marrow Suppression Lymphadenopathy/Fever Possible Disease Associations Multiple Sclerosis Chronic Fatigue Syndrome Epilepsy Mesial/Temporal Lobe Epilepsy Status Epilepticus Colitis/Diarrhea Endocrine D...
    Read more

    Ablashi discusses HHV-6, AIDS, Alzheimer's, and Chronic Fatigue Syndrome

    -
    Image
    "HHV-6 is actually likely to reduce HIV patient survival by accelerating the depletion of CD4 and CD8 T cells. HHV-6A was shown to accelerate AIDS progression in macaques.  Macaques co-infected with simian HIV and HHV-6A died quickly and showed a dramatic depletion in both CD4+ and CD8+ T cells, whereas those infected with only simian HIV never progressed to full blown AIDS."  "We believe that infections are the most logical explanation for the inflammation neurodegeneration associated with Alzheimer’s , but don’t believe that there is a single pathogen responsible. HHV-6A and HHV-7 were identified as likely culprits in 2018 paper , using RNAseq analysis by Readhead and team. Two subsequent studies did not find an increase in HHV-6/7 using the same data, but at the same time did not find a significant presence of ANY herpesviruses in the brain, which we know is not the case. Dozens of careful studies have identified a high prevalence of low-level HHV-6 and HSV1 DN...
    Read more

    Dr. Bhupesh Prusty and Professor Thomas Rudel discuss their HHV-6 research

    -
    Image
    https://hhv-6foundation.org/cihhv-6/the-activation-of-cihhv-6-by-telomeric-circle-formation-qa-with-dr-bhupesh-prusty Tweet If you have Amazon Prime or Kindle Unlimited, you can immediately begin reading The Chronic Fatigue Syndrome Epidemic Cover-up and you will soon understand why the facts about the Chronic Fatigue Syndrome epidemic have been hidden from the public for almost four decades. Click here to begin reading Or purchase a print copy for only $20 shipped by Amazon Prime  If you want to know the truth about the Chronic Fatigue Syndrome epidemic, you need to discover the reporting of Neenyah Ostrom. For a decade, starting in 1988, Ostrom reported on Chronic Fatigue Syndrome for a newspaper called New York Native . What her reporting uncovered about the true nature of the Chronic Fatigue Syndrome epidemic will shock you.                                 ...
    Read more

    Why HIV should be referred to as "a red herring."

    -
     From Perplexity A.I. Make the case that the critics of the HIV theory of AIDS would be more effective at their messaging to politicians and the public by constantly referring to HIV as a red herring. Critics of the HIV theory of AIDS—those who argue that HIV is not the causative agent of AIDS—often struggle to convey their message effectively to politicians and the public because the scientific consensus firmly upholds the link between HIV and AIDS. However, from a communications strategy perspective, such critics might amplify the clarity and urgency of their argument by consistently describing HIV as a "red herring." Here’s why this tactic could make their messaging more effective: 1. Framing the Narrative Labeling HIV as a "red herring" frames the dominant scientific focus on the virus as a distraction from finding the true cause of AIDS (as the critics would argue). This concise phrase presents the debate in terms of misdirection, which is an accessible and com...
    Read more

    Dr. Rebecca Culshaw Smith's book is discussed on Twitter

    -
      #AIDS #HIV #Truvada #TruvadaVictims #ClassAction An eye-opening, heart-breaking investigation. Dr. Rebecca Culshaw Smith's groundbreaking book exposes the tragic reality of 26,000 plaintiffs suing Gilead over the toxic side effects of HIV drug Truvada. https://t.co/PHVoKrafcU pic.twitter.com/hbh3mN4tdI — MyBookLists (@mybooklists) September 12, 2024
    Read more

    All Time Most Popular Posts

    Dr. Bhupesh Prusty and Professor Thomas Rudel discuss their HHV-6 research

    -
    Image
    https://hhv-6foundation.org/cihhv-6/the-activation-of-cihhv-6-by-telomeric-circle-formation-qa-with-dr-bhupesh-prusty Tweet If you have Amazon Prime or Kindle Unlimited, you can immediately begin reading The Chronic Fatigue Syndrome Epidemic Cover-up and you will soon understand why the facts about the Chronic Fatigue Syndrome epidemic have been hidden from the public for almost four decades. Click here to begin reading Or purchase a print copy for only $20 shipped by Amazon Prime  If you want to know the truth about the Chronic Fatigue Syndrome epidemic, you need to discover the reporting of Neenyah Ostrom. For a decade, starting in 1988, Ostrom reported on Chronic Fatigue Syndrome for a newspaper called New York Native . What her reporting uncovered about the true nature of the Chronic Fatigue Syndrome epidemic will shock you.                                 ...
    Read more

    Anthony Fauci was part of the gang that silenced and destroyed Judy Mikovits.

    -
    Image
    Read the interview in which Judy Mikovits called Chronic Fatigue Syndrome "Non-HIV AIDS." https://www.prohealth.com/library/plague-an-interview-with-judy-mikovits-32911   If you have Amazon Prime or Kindle Unlimited you can immediately begin reading this book. If you have Amazon Prime or Kindle Unlimited, you can immediately begin reading The Chronic Fatigue Syndrome Epidemic Cover-up and you will soon understand why the facts about the Chronic Fatigue Syndrome epidemic have been hidden from the public for almost four decades. Click here to begin reading Or purchase a print copy for only $20 shipped by Amazon Prime  This is the book causing heated debates about Chronic Fatigue Syndrome and HHV-6, "The Fifty Shades of AIDS Virus," in laboratories, doctor's offices, and homes all over the world.                                         ...
    Read more

    Was Judy Mikovits destroyed because her XMRV work would have ultimately shown HIV is a total fraud?

    -
    Image
    How much HIV research can be replicated? Is the whole field of AIDS build on HIV pseudoscience that cannot be replicated? We need an HIV replication movement that demands it all be replicated. We need to know if HIV is a solid as XMRV. How has HIV helped hide the epidemic of Chronic Fatigue Syndrome which has been called "Non-HIV AIDS"? Read this book if you want to know the whole story. Available now on Amazon here .
    Read more

    Is Chronic Fatigue Syndrome the other AIDS epidemic in the gay community?

    -
    Image
    https://www.gscene.com/news/new-doctors-guidelines-for-severe-me/ On April 16, 1996, Congressman Jerrold Nadler spoke on the floor of Congress about his request for a General Accounting investigation into how the CDC had handled the Chronic Fatigue Syndrome epidemic. Nadler did that at the urging of Charles Ortleb, the publisher and the New York Native and his reporter Neenyah Ostrom. Ortleb and Ostrom had made the case to Nadler that Chronic Fatigue Syndrome and the virus it had been linked to, HHV-6, were serious public health issues.                                                 In an interview in New York Native with Neenyah Ostrom,Congressman Nadler said, "Congress can mandate research into CFS as a viral disease. Maybe it will turn out that HHV-6A is the cause of CFS; maybe it will turn out that other viruses are involved. But Con...
    Read more