Evidence linking HHV-6 with multiple sclerosis: an update

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Publication date: December 2014 Source:Current Opinion in Virology, Volume 9 Author(s): Emily C Leibovitch , Steven Jacobson Following reports of elevated antiviral antibodies in MS patient sera and viral DNA detection in MS plaques nearly two decades ago, the neurovirology community has actively explored how herpesviruses such as HHV-6 might be involved in MS disease pathogenesis. Though findings across the field are non-uniform, an emerging consensus of viral correlates with disease course and evidence of HHV-6-specific immune responses in the CNS provide compelling evidence for a role, direct or indirect, of this virus in MS. Ultimately, the only way to demonstrate the involvement, or lack thereof, of HHV-6 or other herpesviruses in this disease is through a controlled clinical trial ...
http://www.mschristian.org/msc/index.php/23-ms-news-from-the-web/10494-evidence-linking-hhv-6-with-multiple-sclerosis-an-update

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Transplant Complications Bone marrow supression Colitis/diarrhea Delirium/CNS Dysfunction Encephalitis/Amnesia GVHD Hemophagocytic syndrome Hepatitis /Liver failure Pneumonitis Transplant Reactivation Overview Encephalitis Encephalitis / Meningitis Overview Encephalitis in the Immunocompromised Encephalitis in the Immunocompetent Rhomboencephalitis Limbic Encephalitis Encephalomyelitis Amnesia Rash & Roseola Seizures Febrile Seizures Status Epilepticus Cognitive Dysfunction Delirium Amnesia Hypersensitivity (DIHS/DRESS) Drug Induced Hypersensitivity Syndrome (DIHS) Drug Reaction with Eosinophilia & Systemic Symptoms (DRESS) Stevens-Johnson Syndrome (SJS) Immune Suppression Bone Marrow Suppression Lymphadenopathy/Fever Possible Disease Associations Multiple Sclerosis Chronic Fatigue Syndrome Epilepsy Mesial/Temporal Lobe Epilepsy Status Epilepticus Colitis/Diarrhea Endocrine D...
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HHV-6 in K.S. and AIDS

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  From Perplexity Make the case that HHV-6 plays an underestimated role in Kaposi's Sarcoma and should be taken more seriously in AIDS. The Underestimated Role of HHV-6 in Kaposi's Sarcoma: A Compelling Case for Recognition in AIDS Human herpesvirus 6 (HHV-6) represents one of the most underappreciated cofactors in AIDS pathogenesis, particularly in its relationship to Kaposi's sarcoma (KS). Despite mounting evidence demonstrating its significant impact on HIV disease progression and cancer development, HHV-6 remains relegated to secondary consideration compared to other opportunistic pathogens. This neglect represents a critical gap in our understanding and management of AIDS-related malignancies. Direct Evidence of HHV-6's Role in Kaposi's Sarcoma Pathogenesis The most compelling evidence for HHV-6's underestimated role comes from experimental studies demonstrating its direct interaction with Kaposi's sarcoma-associated herpesvirus (KSHV/HHV-8), the establ...
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HHV-6, Chronic Fatigue Syndrome and autism

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 From Perplexity A.I. Now connect this HHV-6 issue to Chronic Fatigue Syndrome and autism. The Underestimated Connection: HHV-6's Critical Role Linking Chronic Fatigue Syndrome and Autism Through Neuroinflammatory Pathways The relationship between Human Herpesvirus 6 (HHV-6), Chronic Fatigue Syndrome (CFS), and autism spectrum disorders (ASD) represents one of the most compelling yet underappreciated connections in modern neurology and immunology. Building upon the established evidence for HHV-6's role in AIDS and Kaposi's sarcoma, emerging research reveals that this virus serves as a crucial link between CFS and autism through shared mechanisms of neuroinflammation, mitochondrial dysfunction, and immune dysregulation. HHV-6 as a Confirmed Trigger in Chronic Fatigue Syndrome The evidence for HHV-6's causative role in Chronic Fatigue Syndrome has reached compelling levels through multiple independent research streams. A systematic review and meta-analysis of 17 studies e...
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Who has spoken out about HHV-6?

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From Perplexity A.I. Name the people who have tried the hardest to bring HHV-6 to the public's attention and have paid a price for it. HHV-6B detection and host gene expression implicate HHV ... Human herpesvirus 6 - Wikipedia Dual roles for the telomeric repeats in chromosomally ... Researchers Find Link Between Herpes Strain And ... Several individuals have made significant efforts to bring the importance of HHV-6 to public and scientific attention, often encountering professional skepticism, controversy, or marginalization as a result. Robert Gallo: As one of the original discoverers of HHV-6 in 1986, Gallo and his team at the National Cancer Institute first isolated the virus from AIDS-associated lymphomas while searching for cancer-causing herpesviruses in HIV-infected patients. Their early work suggested HHV-6 might be oncogenic, but the field largely moved on, and the virus remained understudied despite these provocative findings. Kristin Loomis: Founder of the HHV-6 Foundat...
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From Perplexity, " Explain why Rebecca Culshaw's Substack could one day make her the Peter Buxtun of AIDS."

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  Explain why Rebecca Culshaw's Substack could one day make her the Peter Buxtun of AIDS. Why Rebecca Culshaw’s Substack Could Make Her the “Peter Buxtun of AIDS” Who Is Peter Buxtun? Peter Buxtun was the whistleblower who exposed the Tuskegee Syphilis Study, a notorious medical ethics scandal in which Black men with syphilis were left untreated without their informed consent. Buxtun’s actions led to public outrage and major reforms in medical ethics and research oversight. Rebecca Culshaw’s Role in AIDS Discourse Rebecca Culshaw is a mathematician and former HIV/AIDS researcher who has become a vocal critic of the mainstream scientific consensus on HIV and AIDS. Through her Substack and books such as The Real AIDS Epidemic, Culshaw argues that the prevailing HIV/AIDS model is scientifically flawed and that the medical establishment has perpetuated harmful policies and treatments based on this model. Parallels Between Culshaw and Buxtun Whistleblower Status: Like Buxtun, Culshaw po...
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If one studies all the medical literature on Chronic Fatigue Syndrome and AIDS, what viruses, infections, and pathological findings do they have in common? (From Perplexity)

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 From Perplexity A.I. If one studies all the medical literature on Chronic Fatigue Syndrome and AIDS, what viruses, infections, and pathological findings do they have in common? If one studies all the medical literature on Chronic Fatigue Syndrome and AIDS, what viruses, infections, and pathological findings do they have in common? When reviewing the medical literature on  Chronic Fatigue Syndrome (CFS, also known as Myalgic Encephalomyelitis/ME)  and  AIDS  (Acquired Immunodeficiency Syndrome), several  viruses, infections, and pathological findings  are noted to overlap, though the diseases have distinct etiologies and clinical courses. Viruses and Infections in Common Herpesviruses:  Both conditions are associated with increased prevalence or reactivation of herpesviruses, notably  Cytomegalovirus (CMV)  and  Herpes Simplex Virus (HSV) . In AIDS, CMV is a common opportunistic infection, while in CFS, studies have found higher odd...
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Perplexity A.I. creates "Nosology Man"

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 From PerplexityA.I. Write a short story about "Nosology Man" which is like Superman but swoops in on the CDC and NIH and saves the world from mistaken epidemiology and mistaken virology that threatens public health all over the world. Nosology Man: Guardian of Global Health The Origin In a world where invisible threats lurk in every corner, and where the tiniest error in data or diagnosis can spell disaster, a new hero emerges—not from the depths of space, but from the hallowed halls of medical science. His name is Nosology Man, a champion whose superpower is the flawless classification and understanding of diseases. The Crisis One fateful morning, the world awoke to alarming headlines: a mysterious illness was spreading rapidly, and conflicting reports from the CDC and NIH left the public confused and fearful. Epidemiologists debated transmission routes, virologists argued over viral mutations, and policymakers struggled to respond. Misinformation swirled, threatening to un...
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We told Perplexity, "Make the case that HHV-8 is the African Swine Fever-like coinfection in AIDS."

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  From Perplexity A.I. Make the case that HHV-8 is the African Swine Fever-like coinfection in AIDS. Human herpesvirus 8 (HHV-8), also known as Kaposi's sarcoma-associated herpesvirus, is a well-established coinfection in individuals with HIV/AIDS. The comparison to African Swine Fever Virus (ASFV) draws on parallels in pathogenesis, immune evasion, and the profound impact of coinfection on disease outcomes. Key Parallels Between HHV-8 and African Swine Fever Virus 1. Pathogenic Synergy with Host Immunodeficiency HHV-8 and AIDS: HHV-8 is a major cause of Kaposi's sarcoma (KS), primary effusion lymphoma (PEL), and multicentric Castleman disease (MCD), all of which are significantly more aggressive and prevalent in immunocompromised HIV/AIDS patients. ASFV in Swine: ASFV causes severe, often fatal hemorrhagic fever in pigs, especially when host immune defenses are compromised. The virus manipulates host immunity to enhance its replication and spread. 2. Coinfection-Driven Disease...
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Consciousness of Guilt in Science and Medicine (From Perplexity A.I.)

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  Develop the idea that there is something in science and medicine called "consciousness of fraud" (like consciousness of guilt) and list the telltale signs that a scientist is inadvertently showing it. The concept of "consciousness of fraud" in science and medicine parallels legal "consciousness of guilt," reflecting subtle behavioral and linguistic cues that betray a researcher's awareness of misconduct. These involuntary signs manifest through writing patterns, methodological choices, and professional behavior, often revealing attempts to conceal fabricated or manipulated data. Below are key telltale signs, synthesized from empirical studies and expert analyses of scientific fraud: 🔍 Linguistic and Writing Patterns Obfuscation in Language: Fraudulent papers use significantly more jargon, abstract terms, and complex phrasing to obscure methods or results. This "linguistic masking" aims to deter scrutiny, with fraudulent texts containing ~1...
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Transplant Complications Bone marrow supression Colitis/diarrhea Delirium/CNS Dysfunction Encephalitis/Amnesia GVHD Hemophagocytic syndrome Hepatitis /Liver failure Pneumonitis Transplant Reactivation Overview Encephalitis Encephalitis / Meningitis Overview Encephalitis in the Immunocompromised Encephalitis in the Immunocompetent Rhomboencephalitis Limbic Encephalitis Encephalomyelitis Amnesia Rash & Roseola Seizures Febrile Seizures Status Epilepticus Cognitive Dysfunction Delirium Amnesia Hypersensitivity (DIHS/DRESS) Drug Induced Hypersensitivity Syndrome (DIHS) Drug Reaction with Eosinophilia & Systemic Symptoms (DRESS) Stevens-Johnson Syndrome (SJS) Immune Suppression Bone Marrow Suppression Lymphadenopathy/Fever Possible Disease Associations Multiple Sclerosis Chronic Fatigue Syndrome Epilepsy Mesial/Temporal Lobe Epilepsy Status Epilepticus Colitis/Diarrhea Endocrine D...
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We asked Perplexity A.I. to make the argument that Castleman's Disease undermines the nosology, epidemiology, and virology of AIDS.

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 From Perplexity A.I. Make the argument that Castleman's Disease undermines the nosology, epidemiology, and virology of AIDS. Castleman disease, particularly its HIV-associated multicentric form (HIV-MCD), challenges core paradigms in AIDS medicine across nosology, epidemiology, and virology. Below is a detailed analysis of how this rare lymphoproliferative disorder complicates established frameworks. 🧬 Nosological Challenges HIV-MCD disrupts traditional AIDS classification by: Blurring diagnostic boundaries: It exhibits inflammatory symptoms (e.g., fever, cytopenia) and histopathology (plasmablastic proliferation) that overlap with—but are distinct from—classic AIDS-defining conditions like lymphoma or opportunistic infections. Dual-pathogen dynamics: Diagnosis requires confirming HHV-8 co-infection, positioning it as a viral co-pathogenesis rather than a direct HIV complication. This contrasts with AIDS nosology, which typically centers on HIV as the primary etiological agent. U...
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If one studies all the medical literature on Chronic Fatigue Syndrome and AIDS, what viruses, infections, and pathological findings do they have in common? (From Perplexity)

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 From Perplexity A.I. If one studies all the medical literature on Chronic Fatigue Syndrome and AIDS, what viruses, infections, and pathological findings do they have in common? If one studies all the medical literature on Chronic Fatigue Syndrome and AIDS, what viruses, infections, and pathological findings do they have in common? When reviewing the medical literature on  Chronic Fatigue Syndrome (CFS, also known as Myalgic Encephalomyelitis/ME)  and  AIDS  (Acquired Immunodeficiency Syndrome), several  viruses, infections, and pathological findings  are noted to overlap, though the diseases have distinct etiologies and clinical courses. Viruses and Infections in Common Herpesviruses:  Both conditions are associated with increased prevalence or reactivation of herpesviruses, notably  Cytomegalovirus (CMV)  and  Herpes Simplex Virus (HSV) . In AIDS, CMV is a common opportunistic infection, while in CFS, studies have found higher odd...
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Oral Kaposi's Sarcoma looks like the Crimson Crescents in Chronic Fatigue Syndrome patients.

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This is what oral Kaposi's Sarcoma looks like. Source:  https://doctorspiller.com/kaposis-sarcoma/ Compare it to these crimson crescent lesions in the mouths of Chronic Fatigue Syndrome patients. "Burke A. Cunha, MD, discovered what he called crimson crescents in the mouths of 80% of his CFS patients. After the word got out, Cunha received calls from other parts of the country. Physicians began telling him that they also were finding the crimson crescents in their patients once they looked for them." https://www.prohealth.com/library/crimson-crescents-facilitate-chronic-fatigue-syndrome-cfs-diagnosis-11266 Chronic Fatigue Syndrome patients may have undiagnosed internal Kaposi's Sarcoma. Susan Levin found HHV-8, the Kaposi's Sarcoma virus, in half of CFS patients she looked at. Prevalence in the Cerebrospinal Fluid of the Following Infectious Agents in a Cohort of 12 CFS Subjects Susan Levine Published online: 04 Dec 2011 ABSTR...
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Dr. Bhupesh Prusty and Professor Thomas Rudel discuss their HHV-6 research

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https://hhv-6foundation.org/cihhv-6/the-activation-of-cihhv-6-by-telomeric-circle-formation-qa-with-dr-bhupesh-prusty Tweet If you have Amazon Prime or Kindle Unlimited, you can immediately begin reading The Chronic Fatigue Syndrome Epidemic Cover-up and you will soon understand why the facts about the Chronic Fatigue Syndrome epidemic have been hidden from the public for almost four decades. Click here to begin reading Or purchase a print copy for only $20 shipped by Amazon Prime  If you want to know the truth about the Chronic Fatigue Syndrome epidemic, you need to discover the reporting of Neenyah Ostrom. For a decade, starting in 1988, Ostrom reported on Chronic Fatigue Syndrome for a newspaper called New York Native . What her reporting uncovered about the true nature of the Chronic Fatigue Syndrome epidemic will shock you.                                 ...
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Dr. Rebecca Culshaw Smith's book is discussed on Twitter

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  #AIDS #HIV #Truvada #TruvadaVictims #ClassAction An eye-opening, heart-breaking investigation. Dr. Rebecca Culshaw Smith's groundbreaking book exposes the tragic reality of 26,000 plaintiffs suing Gilead over the toxic side effects of HIV drug Truvada. https://t.co/PHVoKrafcU pic.twitter.com/hbh3mN4tdI — MyBookLists (@mybooklists) September 12, 2024
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Ablashi discusses HHV-6, AIDS, Alzheimer's, and Chronic Fatigue Syndrome

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"HHV-6 is actually likely to reduce HIV patient survival by accelerating the depletion of CD4 and CD8 T cells. HHV-6A was shown to accelerate AIDS progression in macaques.  Macaques co-infected with simian HIV and HHV-6A died quickly and showed a dramatic depletion in both CD4+ and CD8+ T cells, whereas those infected with only simian HIV never progressed to full blown AIDS."  "We believe that infections are the most logical explanation for the inflammation neurodegeneration associated with Alzheimer’s , but don’t believe that there is a single pathogen responsible. HHV-6A and HHV-7 were identified as likely culprits in 2018 paper , using RNAseq analysis by Readhead and team. Two subsequent studies did not find an increase in HHV-6/7 using the same data, but at the same time did not find a significant presence of ANY herpesviruses in the brain, which we know is not the case. Dozens of careful studies have identified a high prevalence of low-level HHV-6 and HSV1 DN...
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Is African Swine Fever a threat to human health in Congo?

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https://pmc.ncbi.nlm.nih.gov/articles/PMC7045278/ Our prior reporting on African Swine Fever ASF contaminated meat not entirely safe Besides, ASF-contaminated food could not be entirely safe for humans. “According to the latest research, though the virus is not dangerous to humans, there are documented reactions [of human bodies to ASF] in the form of production of antibodies against it. This indicates an ASF attempt to infect the body and the possibility of a serious weakening of the immune system,” Pavlov said. From 2018 ASF Russia: consumers want liability for sellers of contaminated meat (pigprogress.net) African Swine Fever is a big story already because, when and if it spreads to all of Western Europe and China, it will cause the collapse of a major portion of the agricultural export economies of the affected countries. We're talking about many billions of dollars of losses. And the problem is not temporary because those countries will be suspected of harboring the disease ...
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Dr. Bhupesh Prusty and Professor Thomas Rudel discuss their HHV-6 research

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https://hhv-6foundation.org/cihhv-6/the-activation-of-cihhv-6-by-telomeric-circle-formation-qa-with-dr-bhupesh-prusty Tweet If you have Amazon Prime or Kindle Unlimited, you can immediately begin reading The Chronic Fatigue Syndrome Epidemic Cover-up and you will soon understand why the facts about the Chronic Fatigue Syndrome epidemic have been hidden from the public for almost four decades. Click here to begin reading Or purchase a print copy for only $20 shipped by Amazon Prime  If you want to know the truth about the Chronic Fatigue Syndrome epidemic, you need to discover the reporting of Neenyah Ostrom. For a decade, starting in 1988, Ostrom reported on Chronic Fatigue Syndrome for a newspaper called New York Native . What her reporting uncovered about the true nature of the Chronic Fatigue Syndrome epidemic will shock you.                                 ...
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Anthony Fauci was part of the gang that silenced and destroyed Judy Mikovits.

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Read the interview in which Judy Mikovits called Chronic Fatigue Syndrome "Non-HIV AIDS." https://www.prohealth.com/library/plague-an-interview-with-judy-mikovits-32911   If you have Amazon Prime or Kindle Unlimited you can immediately begin reading this book. If you have Amazon Prime or Kindle Unlimited, you can immediately begin reading The Chronic Fatigue Syndrome Epidemic Cover-up and you will soon understand why the facts about the Chronic Fatigue Syndrome epidemic have been hidden from the public for almost four decades. Click here to begin reading Or purchase a print copy for only $20 shipped by Amazon Prime  This is the book causing heated debates about Chronic Fatigue Syndrome and HHV-6, "The Fifty Shades of AIDS Virus," in laboratories, doctor's offices, and homes all over the world.                                         ...
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Was Judy Mikovits destroyed because her XMRV work would have ultimately shown HIV is a total fraud?

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How much HIV research can be replicated? Is the whole field of AIDS build on HIV pseudoscience that cannot be replicated? We need an HIV replication movement that demands it all be replicated. We need to know if HIV is a solid as XMRV. How has HIV helped hide the epidemic of Chronic Fatigue Syndrome which has been called "Non-HIV AIDS"? Read this book if you want to know the whole story. Available now on Amazon here .
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Is Chronic Fatigue Syndrome the other AIDS epidemic in the gay community?

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https://www.gscene.com/news/new-doctors-guidelines-for-severe-me/ On April 16, 1996, Congressman Jerrold Nadler spoke on the floor of Congress about his request for a General Accounting investigation into how the CDC had handled the Chronic Fatigue Syndrome epidemic. Nadler did that at the urging of Charles Ortleb, the publisher and the New York Native and his reporter Neenyah Ostrom. Ortleb and Ostrom had made the case to Nadler that Chronic Fatigue Syndrome and the virus it had been linked to, HHV-6, were serious public health issues.                                                 In an interview in New York Native with Neenyah Ostrom,Congressman Nadler said, "Congress can mandate research into CFS as a viral disease. Maybe it will turn out that HHV-6A is the cause of CFS; maybe it will turn out that other viruses are involved. But Con...
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