Is this the reason Covid-19 has broken out at pork plants?

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Abstract
 The ongoing SARS-CoV-2 pandemic is the third zoonotic coronavirus identified in the last twenty years. Previously, four other known coronaviruses moved from animal reservoirs into humans and now cause primarily mild-to-moderate respiratory disease. The emergence of these viruses likely involved a period of intense transmission before becoming endemic, highlighting the recurrent threat to human health posed by animal coronaviruses. Enzootic and epizootic coronaviruses of diverse lineages pose a significant threat to livestock, as most recently observed for virulent strains of porcine epidemic diarrhea virus (PEDV) and swine acute diarrhea-associated coronavirus (SADS-CoV). Unique to RNA viruses, coronaviruses encode a proofreading exonuclease (ExoN) that lowers point mutation rates to increase the viability of large RNA virus genomes, which comes with the cost of limiting virus adaptation via point mutation. This limitation can be overcome by high rates of recombination that facilitate rapid increases in genetic diversification. To compare dynamics of recombination between related sequences, we developed an open-source computational workflow (IDPlot) to measure nucleotide identity, locate recombination breakpoints, and infer phylogenetic relationships. We analyzed recombination dynamics among three groups of coronaviruses with impacts on livestock or human health: SARSr-CoV, Betacoronavirus-1, and SADSr-CoV. We found that all three groups undergo recombination with highly diverged viruses, disrupting phylogenetic relationships and revealing contributions of unknown coronavirus lineages to the genetic diversity of established groups. Dynamic patterns of recombination impact inferences of relatedness between diverse coronaviruses and expand the genetic pool that may contribute to future zoonotic events. These results illustrate the limitations of current sampling approaches for anticipating zoonotic threats to human and animal health

 Extensive recombination-driven coronavirus diversification expands the pool of potential pandemic pathogens (biorxiv.org)

Popular Posts in the Last 7 Days

If one assumeS Rebecca Culshaw's Substack is correct, what were 20 moments in the last 40 ears when scientist should have recognized something was wrong in the HIV/AIDS paradigm?

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From Perplexity A.I.   Assuming Rebecca Culshaw's Substack and books are correct, here are 20 moments in the last 40 years when scientists should have recognized fundamental problems in the HIV/AIDS paradigm, based on major controversies, failed predictions, and repeatedly anomalous findings highlighted by critics like Culshaw and others: Key Moments Highlighting Paradigm Failures 1984: Early claims of HIV as the sole cause of AIDS were made before conclusive evidence, leading to widespread adoption of a viral paradigm without rigorous challenge or alternate hypothesis consideration. ​ Mid-1980s: Discovery disputes between Luc Montagnier (France) and Robert Gallo (US) over the "AIDS virus" involved accusations of sample misappropriation and scientific misconduct, but were glossed over for the sake of an international consensus. ​ 1987: Peter Duesberg publicly challenged the HIV-AIDS causation model, noting unanswered questions around risk group disease patterns and viral ...
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A Perplexity conversation about self-deceit, conspiracy, Arendt and AIDS

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  Discuss the confusion between the appearance of conspiracy and self-deceit, and how self-deceit in government leaders creates the appearance of conspiracy. Self-deceit in government leaders can powerfully create the appearance of conspiracy, even when there is no coordinated secret plot. When leaders convince themselves of the righteousness or effectiveness of their own policies, they may unconsciously deny evidence of harm, ignore ethical contradictions, or adopt comforting narratives rather than confront uncomfortable truths. Other observers, detecting this disconnect between official statements and lived reality, may then perceive hidden motives, deliberate cover-ups, or coordinated deception—classic ingredients of conspiracy suspicions—even if the real dynamic is psychological denial and bureaucratic inertia. ​ This confusion arises because self-deceit can mimic true conspiracy: it generates secrecy, ritualized language, and the concealment of damaging realities, not by inten...
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Activation of endogenous retrovirus reverse transcriptase in multiple sclerosis patient lymphocytes by inactivated HSV-1, HHV-6 and VZV

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  Activation of endogenous retrovirus reverse transcriptase in multiple sclerosis patient lymphocytes by inactivated HSV-1, HHV-6 and VZV - Aarhus University Abstract Human endogenous retroviruses (HERVs) and herpesviruses have been associated with the development of multiple sclerosis (MS). These virus groups interact with each other and have been shown to induce synergistic immune responses. Here, we focus on the possible role of herpesviruses as contributing factors in HERV activation. We demonstrate the ability of HSV-1, HHV-6, and VZV antigens to induce higher RT activity in peripheral lymphocytes from MS patients vs. controls during the first 6 days post-antigen stimulation. On subsequent days, only VZV can sustain the increase in the RT expression in cells from MS patients. The RT induction does not depend on herpes replication.
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Gallo's early statements about HHV-6

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Gallo's early statements about HHV-6 are discussed in this excerpt from Nick Regush's The Virus Within (page. 13).   When NCI laboratory research revealed the extent of HHV-6's destructive power, Robert Gallo began to speak out about the implications. On May 10, 1988, at the annual meeting of the American Society of Microbiology in Miami, he told an audience that HHV-6 had been found along with HIV in T-4 cells, and speculated that the new herpes virus could be a "co-factor" in AIDS. One month later, at an international AIDS conference in Stockholm, he explained that HHV-6 killed T-4 cells in the test tube more effectively than did HIV, and said the new herpes virus could cause massive cell death. Gallo reasoned that HHV-6 infection might help speed up the HIV-led breakdown of the immune system in AIDS, although he cautioned that NCI research on HHV-6 was still preliminary. The Virus Within: A Coming Epidemic: Regush, Nicholas: 9780525945345: Amazon.com: Books
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A conversation with Perplexity about Camus and Rebecca Culshaw Smith

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  In what book or essay did Camus talk about priests in earlier centuries walk prisoners to their executions holding masks up in front of them? Albert Camus discussed the practice of priests accompanying prisoners to their executions and using masks to shield them in his essay "Reflections on the Guillotine" (1957). This extended essay addresses the death penalty and details the various rituals and psychological impacts surrounding execution, including the presence and actions of priests in earlier centuries. Camus examines how clergy would sometimes hold masks up before the faces of condemned individuals on their final walk, highlighting the historical blend of piety and cruelty within capital punishment practices. What is the passage? The passage Camus wrote about priests holding masks in front of prisoners as they walked to executions appears in "Reflections on the Guillotine." He describes how, in earlier centuries, a priest would accompany the condemned to the ...
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New cartoon

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From a forthcoming Julian Lake collection of cartoons about P-hacking in AIDS and Chronic Fatigue Syndrome research. Don't know what P-hacking is? Read this article in the New York Times . Julian Lake most recent collection of cartoons about Chronic Fatigue Syndrome and AIDS is here . See more of Julian Lake's P-hacking cartoon at P-hack University . To learn more about the P-hacking culture of AIDS, Chronic Fatigue Syndrome, and public health science at the CDC and NIH, read Truth to Power , or Iatrogenocide , or if you really have a sense of humor and like wicked satire, Pig: A Memoir .
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Perplexity on the implications of Rebecca Culshaw Smith's critique of HIV

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  The nosological, or disease-classification, paradigm of AIDS has indeed often been shaped by social, political, and ideological factors—reflecting what people wanted the disease to be, rather than what it necessarily   was   in purely biomedical terms. This phenomenon manifests in how AIDS was conceptualized, named, and managed over time, combining cultural anxieties and political agendas with scientific investigation. Politicized Beginnings and Cultural Framing When AIDS first appeared in the early 1980s, its definition was heavily influenced by the sociopolitical climate of the United States. It emerged amidst moral panic surrounding homosexuality, drug use, and sexuality—conditions viewed as “deviant” by mainstream society. The term “AIDS,” coined to replace the earlier “GRID” (Gay-Related Immune Deficiency), still carried moral and religious overtones that reflected cultural discomfort more than clear etiological understanding. Stigma, moral judgment, and political ...
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 The 1992 Amsterdam International AIDS Conference can be viewed as a critical—but neglected—turning point that exposed cracks in the prevailing HIV/AIDS paradigm. It brought together mounting evidence of immunodeficiencies not fully explained by HIV alone and coincided with emerging research linking Chronic Fatigue Syndrome (CFS) to AIDS-like immune dysfunction. Had these signals been integrated, the conference could have become a “Black Swan” event—an inflection point forcing the scientific establishment to reassess the single-virus causation model and to acknowledge parallel disease mechanisms. The Missed Black Swan Moment The Amsterdam Conference occurred at a moment of scientific unease. By 1992, death rates were escalating despite monotherapy with AZT, and leading researchers debated whether HIV alone could explain the spectrum of immune collapse being observed. Alternative views were gaining quiet traction, suggesting co-factors such as immune activation, oxidative stress, an...
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If one assumeS Rebecca Culshaw's Substack is correct, what were 20 moments in the last 40 ears when scientist should have recognized something was wrong in the HIV/AIDS paradigm?

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From Perplexity A.I.   Assuming Rebecca Culshaw's Substack and books are correct, here are 20 moments in the last 40 years when scientists should have recognized fundamental problems in the HIV/AIDS paradigm, based on major controversies, failed predictions, and repeatedly anomalous findings highlighted by critics like Culshaw and others: Key Moments Highlighting Paradigm Failures 1984: Early claims of HIV as the sole cause of AIDS were made before conclusive evidence, leading to widespread adoption of a viral paradigm without rigorous challenge or alternate hypothesis consideration. ​ Mid-1980s: Discovery disputes between Luc Montagnier (France) and Robert Gallo (US) over the "AIDS virus" involved accusations of sample misappropriation and scientific misconduct, but were glossed over for the sake of an international consensus. ​ 1987: Peter Duesberg publicly challenged the HIV-AIDS causation model, noting unanswered questions around risk group disease patterns and viral ...
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Perplexity on the AIDS paradigm

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  Make the case that a major shift in the HIV/AIDS paradigm could be one of the biggest earthquakes to hit science and medicine in history. A major shift in the HIV/AIDS paradigm would constitute one of the most profound intellectual and institutional earthquakes in the history of science and medicine. It would challenge not only the biomedical understanding of a virus and its pathology but also the sociopolitical and economic infrastructure that has grown around HIV research, treatment, and policy for over four decades. Such a transformation would rival the Copernican, Darwinian, or germ theory revolutions in scope and consequence. [1] [2] [3] The Structure of a Paradigm Shift Thomas Kuhn’s classical model of scientific revolutions shows that a paradigm shift fractures scientific consensus when anomalies accumulate that cannot be explained by the reigning theory. HIV/AIDS research has long been dominated by the biomedical paradigm , which locates the cause of immune coll...
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Ablashi discusses HHV-6, AIDS, Alzheimer's, and Chronic Fatigue Syndrome

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"HHV-6 is actually likely to reduce HIV patient survival by accelerating the depletion of CD4 and CD8 T cells. HHV-6A was shown to accelerate AIDS progression in macaques.  Macaques co-infected with simian HIV and HHV-6A died quickly and showed a dramatic depletion in both CD4+ and CD8+ T cells, whereas those infected with only simian HIV never progressed to full blown AIDS."  "We believe that infections are the most logical explanation for the inflammation neurodegeneration associated with Alzheimer’s , but don’t believe that there is a single pathogen responsible. HHV-6A and HHV-7 were identified as likely culprits in 2018 paper , using RNAseq analysis by Readhead and team. Two subsequent studies did not find an increase in HHV-6/7 using the same data, but at the same time did not find a significant presence of ANY herpesviruses in the brain, which we know is not the case. Dozens of careful studies have identified a high prevalence of low-level HHV-6 and HSV1 DN...
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Oral Kaposi's Sarcoma looks like the Crimson Crescents in Chronic Fatigue Syndrome patients.

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This is what oral Kaposi's Sarcoma looks like. Source:  https://doctorspiller.com/kaposis-sarcoma/ Compare it to these crimson crescent lesions in the mouths of Chronic Fatigue Syndrome patients. "Burke A. Cunha, MD, discovered what he called crimson crescents in the mouths of 80% of his CFS patients. After the word got out, Cunha received calls from other parts of the country. Physicians began telling him that they also were finding the crimson crescents in their patients once they looked for them." https://www.prohealth.com/library/crimson-crescents-facilitate-chronic-fatigue-syndrome-cfs-diagnosis-11266 Chronic Fatigue Syndrome patients may have undiagnosed internal Kaposi's Sarcoma. Susan Levin found HHV-8, the Kaposi's Sarcoma virus, in half of CFS patients she looked at. Prevalence in the Cerebrospinal Fluid of the Following Infectious Agents in a Cohort of 12 CFS Subjects Susan Levine Published online: 04 Dec 2011 ABSTR...
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Why HIV should be referred to as "a red herring."

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 From Perplexity A.I. Make the case that the critics of the HIV theory of AIDS would be more effective at their messaging to politicians and the public by constantly referring to HIV as a red herring. Critics of the HIV theory of AIDS—those who argue that HIV is not the causative agent of AIDS—often struggle to convey their message effectively to politicians and the public because the scientific consensus firmly upholds the link between HIV and AIDS. However, from a communications strategy perspective, such critics might amplify the clarity and urgency of their argument by consistently describing HIV as a "red herring." Here’s why this tactic could make their messaging more effective: 1. Framing the Narrative Labeling HIV as a "red herring" frames the dominant scientific focus on the virus as a distraction from finding the true cause of AIDS (as the critics would argue). This concise phrase presents the debate in terms of misdirection, which is an accessible and com...
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Dr. Bhupesh Prusty and Professor Thomas Rudel discuss their HHV-6 research

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https://hhv-6foundation.org/cihhv-6/the-activation-of-cihhv-6-by-telomeric-circle-formation-qa-with-dr-bhupesh-prusty Tweet If you have Amazon Prime or Kindle Unlimited, you can immediately begin reading The Chronic Fatigue Syndrome Epidemic Cover-up and you will soon understand why the facts about the Chronic Fatigue Syndrome epidemic have been hidden from the public for almost four decades. Click here to begin reading Or purchase a print copy for only $20 shipped by Amazon Prime  If you want to know the truth about the Chronic Fatigue Syndrome epidemic, you need to discover the reporting of Neenyah Ostrom. For a decade, starting in 1988, Ostrom reported on Chronic Fatigue Syndrome for a newspaper called New York Native . What her reporting uncovered about the true nature of the Chronic Fatigue Syndrome epidemic will shock you.                                 ...
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All Time Most Popular Posts

Dr. Bhupesh Prusty and Professor Thomas Rudel discuss their HHV-6 research

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Image
https://hhv-6foundation.org/cihhv-6/the-activation-of-cihhv-6-by-telomeric-circle-formation-qa-with-dr-bhupesh-prusty Tweet If you have Amazon Prime or Kindle Unlimited, you can immediately begin reading The Chronic Fatigue Syndrome Epidemic Cover-up and you will soon understand why the facts about the Chronic Fatigue Syndrome epidemic have been hidden from the public for almost four decades. Click here to begin reading Or purchase a print copy for only $20 shipped by Amazon Prime  If you want to know the truth about the Chronic Fatigue Syndrome epidemic, you need to discover the reporting of Neenyah Ostrom. For a decade, starting in 1988, Ostrom reported on Chronic Fatigue Syndrome for a newspaper called New York Native . What her reporting uncovered about the true nature of the Chronic Fatigue Syndrome epidemic will shock you.                                 ...
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Anthony Fauci was part of the gang that silenced and destroyed Judy Mikovits.

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Read the interview in which Judy Mikovits called Chronic Fatigue Syndrome "Non-HIV AIDS." https://www.prohealth.com/library/plague-an-interview-with-judy-mikovits-32911   If you have Amazon Prime or Kindle Unlimited you can immediately begin reading this book. If you have Amazon Prime or Kindle Unlimited, you can immediately begin reading The Chronic Fatigue Syndrome Epidemic Cover-up and you will soon understand why the facts about the Chronic Fatigue Syndrome epidemic have been hidden from the public for almost four decades. Click here to begin reading Or purchase a print copy for only $20 shipped by Amazon Prime  This is the book causing heated debates about Chronic Fatigue Syndrome and HHV-6, "The Fifty Shades of AIDS Virus," in laboratories, doctor's offices, and homes all over the world.                                         ...
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Was Judy Mikovits destroyed because her XMRV work would have ultimately shown HIV is a total fraud?

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How much HIV research can be replicated? Is the whole field of AIDS build on HIV pseudoscience that cannot be replicated? We need an HIV replication movement that demands it all be replicated. We need to know if HIV is a solid as XMRV. How has HIV helped hide the epidemic of Chronic Fatigue Syndrome which has been called "Non-HIV AIDS"? Read this book if you want to know the whole story. Available now on Amazon here .
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Is Chronic Fatigue Syndrome the other AIDS epidemic in the gay community?

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https://www.gscene.com/news/new-doctors-guidelines-for-severe-me/ On April 16, 1996, Congressman Jerrold Nadler spoke on the floor of Congress about his request for a General Accounting investigation into how the CDC had handled the Chronic Fatigue Syndrome epidemic. Nadler did that at the urging of Charles Ortleb, the publisher and the New York Native and his reporter Neenyah Ostrom. Ortleb and Ostrom had made the case to Nadler that Chronic Fatigue Syndrome and the virus it had been linked to, HHV-6, were serious public health issues.                                                 In an interview in New York Native with Neenyah Ostrom,Congressman Nadler said, "Congress can mandate research into CFS as a viral disease. Maybe it will turn out that HHV-6A is the cause of CFS; maybe it will turn out that other viruses are involved. But Con...
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