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Friday, October 23, 2015

Bulletin #99 from the Coordinating Committee of The International HHV-6 Protest and Teach-in at Harvard (November 9-11, 2015)

Response to valganciclovir in chronic fatigue syndrome patients with human herpesvirus 6 and Epstein–Barr virus IgG antibody titers

 Valganciclovir has been reported to improve physical and cognitive symptoms in patients with chronic fatigue syndrome (CFS) with elevated human herpesvirus 6 (HHV-6) and Epstein-Barr virus (EBV) IgG antibody titers. This study investigated whether antibody titers against HHV-6 and EBV were associated with clinical response to valganciclovir in a subset of CFS patients. An uncontrolled, unblinded retrospective chart review was performed on 61 CFS patients treated with 900 mg valganciclovir daily (55 of whom took an induction dose of 1,800 mg daily for the first 3 weeks). Antibody titers were considered high if HHV-6 IgG ≥ 1:320, EBV viral capsid antigen (VCA) IgG ≥ 1:640, and EBV early antigen (EA) IgG ≥ 1:160. Patients self-rated physical and cognitive functioning as a percentage of their functioning prior to illness. Patients were categorized as responders if they experienced at least 30% improvement in physical and/or cognitive functioning. Thirty-two patients (52%) were categorized as responders. Among these, 19 patients (59%) responded physically and 26 patients (81%) responded cognitively. Baseline antibody titers showed no significant association with response. After treatment, the average change in physical and cognitive functioning levels for all patients was +19% and +23%, respectively (P < 0.0001). Longer treatment was associated with improved response (P = 0.0002). No significant difference was found between responders and non-responders among other variables analyzed. Valganciclovir treatment, independent of the baseline antibody titers, was associated with self-rated improvement in physical and cognitive functioning for CFS patients who had positive HHV-6 and/or EBV serologies. Longer valganciclovir treatment correlated with an improved response.


Journal of Medical VirologyVolume 84, Issue 12, pages 1967–1974, December 2012

 

 

FREQUENTLY ASKED QUESTIONS about the International HHV-6 Protest and Teach-in at Harvard November 9-11, 2015

Art, Cartoons, and Posters for the International HHV-6 Protest and Teach-in at Harvard (November 9-11, 2015)

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Bulletins from The Coordinating Committee of The International HHV-6 Protest and Teach-in At Harvard (November 9-11, 2015)

The Harvard Declaration of the HHV-6 Rights of Man
1. The right not to be lied to about the role of HHV-6 in AIDS.
2. The right not to be lied to about the role of HHV-6 in Chronic Fatigue Syndrome.
3. The right not to be lied to about the role of HHV-6 in Autism.
4.The right not to be lied to about the role of HHV-6 in Multiple Sclerosis.
5. The right not to be lied to about the role of HHV-6 in Brain Cancer.
6. The right not to be lied to about the role of HHV-6 in Heart Disease.
7. The right not to be lied to about the role of HHV-6 in Encephalitis.
8. The right not to be lied to about the role of HHV-6 in Cognitive Dysfunction.
9. The right not to be lied to about the role of HHV-6 in Drug Hypersensitivity Syndrome.
10. The right not to be lied to about the role of HHV-6 in Bone Marrow Suppression.
11. The right not to be lied to about the role of HHV-6 in Lymphadenopathy.
 12. The right not to be lied to about the role of HHV-6 in Colitis.
13. The right not to be lied to about the role of HHV-6 in Endocrine Disorders.
14. The right not to be lied to about the role of HHV-6 in Liver Disease.
 15. The right not to be lied to about the role of HHV-6 in Hodgkin's Lymphoma.
 16. The right not to be lied to about the role of HHV-6 in Glioma.
17. The right not to be lied to about the role of HHV-6 in Cervical Cancer.
18. The right not to be lied to about the role of HHV-6 in Hypogammaglobulinemia.
 19. The right not to be lied to about the role of HHV-6 in Optic Neuritis.
20. The right not to be lied to about the role of HHV-6 in Microangiopathy.
21. The right not to be lied to about the role of HHV-6 in Mononucleosis.
22. The right not to be lied to about the role of HHV-6 in Uveitis.
23. The right not to be lied to about the role of HHV-6 in Stevens-Johnson Syndrome.
24. The right not to be lied to about the role of HHV-6 in Rhomboencephalitis.
25. The right not to be lied to about the role of HHV-6 in Limbic Encephalitis.
26. The right not to be lied to about the role of HHV-6 in Encephalomyelitis
27. The right not to be lied to about the role of HHV-6 in Pneumonitis.
28. The right not to be lied to about the role of HHV-6 in GVHD.
29. The right not to be lied to about the role of HHV-6 in Ideopathic Pneumonia.
30. The right not to be lied to about the role of HHV-6 in Pediatric Adrenocortical Tumors
31. The right not to be lied to about the role of HHV-6 in the reactivation of endogenous retroviruses.
32. The right not to be lied to about the impact of HHV-6 on T-Cells.
33. The right not to be lied to about the impact of HHV-6 on B-Cells
34. The right not to be lied to about the impact of HHV-6 on Epithelial Cells.
35. The right not to be lied to about the the impact of HHV-6 on Natural Killer Cells.
36. The right not to be lied to about the the impact of HHV-6 on Dendritic Cells.
37. The right not to be lied to about the the impact of HHV-6 infection of the brain.
 38. The right not to be lied to about the the impact of HHV-6 infection of the liver.
39. The right not to be lied to about the ability of HHV-6 to affect cytokine production.
40. The right not to be lied to about the ability of HHV-6 to affect Aortic and Heart Microvascular Endothelial cells.
41. The right not to be lied to about the role of an HHV-6 cover-up in a massive HIV Fraud Ponzi Scheme that in a number of ways resembles the Tuskegee Syphilis Experiment and Nazi medicine.

 

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