aocalypse

Friday, March 31, 2017

Detection of Novel Sequences Related to African Swine Fever Virus in Human Serum and Sewage

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2786824/

How Russia can take the lead in HHV-6 research.

Scientists in Russia can help advance the field of HHV-6 research by answering these questions:

1. Is HHV-6 the real AIDS virus?

2. Does HHV-6 cause a Superantigen disease by inducing HERV-K18?

3. Are we in the middle of an HHV-6 epidemic that involves Chronic Fatigue Syndrome and dozens of other disease manifestations?

4. Is HHV-6 really a pig virus?

5. Are pigs infected with a form of HHV-6?

6. Is HHV-8 also a pig virus?

7. Is HHV-6 really a form of African Swine Fever Virus?

8. Is HHV-8 also a  form of African Swine Fever Virus and does that explain why Sardinia has problems with both ASFV and HHV-8?

9. Is HIV really a huge fraud resulting from mistaking HERV-K18 for HIV?

10. Would pigs make the best animal model for HHV-6?

11. Would pigs also make the best animal model for HHV-8?

12. When you infect pigs with HHV-6 or HHV-8 do they develop symptoms of African Swine Fever Virus?

13. Is HHV-6 also the cause of the autism epidemic?

14. Do children with autism get better when you treat their HHV-6 infection with antivirals?







Saturday, March 25, 2017

Is the HHV-6 epidemic keeping a lot of men out of the workforce?

http://www.msn.com/en-us/money/markets/the-mystery-of-why-so-many-american-men-arent-working/ar-BByAUiG?ocid=spartanntp



Charles Ortleb’s Truth to Power takes you inside the New York Native, one of the most unique and consequential newspapers of the twentieth century. Shortly after starting his small gay New York City newspaper in late 1980, one of the biggest scientific and political stories of our time fell into his lap in the form of the AIDS and Chronic Fatigue Syndrome epidemic. What he did with that story has secured his newspaper’s place in history. Under his guidance, a succession of intrepid journalists did some of their greatest work uncovering the crucial facts about the labyrinthine epidemic.

Ortleb made the decision to follow the facts wherever they led. His team of uncompromising investigative reporters inevitably stepped on the toes of the most powerful people in the medical and political establishment. Perhaps not surprisingly, the latter fought back by seeking to discredit the New York Native and even, in time, close its doors. But Ortleb stood his ground for as long as possible and as a result the world now can have a clear understanding of the relationship of AIDS, Chronic Fatigue Syndrome, and HHV-6, the transmissible virus that now threatens everyone on this planet.

Anyone who has wondered why the medical establishment will not tell the truth about the Chronic Fatigue Syndrome epidemic will find the disturbing answer in Truth to Power.

What makes Ortleb so unusual is that not only did he have the natural instincts of a journalist, editor and publisher, but he was also a poet, a fiction writer and a budding political philosopher. Truth to Power is not just a compelling work of journalism and history, but also a major contribution to the intellectual life of our time.

“Charles Ortleb, as editor-in-chief and publisher of the New York Native, was and remains the Izzy Stone of science reporting. He was fearless in his pursuit of the origins of the AIDS epidemic and the government’s response in the 1980s. When his newspaper began to diverge from the dogmatic mainstream, however, he was ostracized by the very people he was seeking to inform. In addition, his laser-like focus in the Native on the simultaneous emergence of so-called “chronic fatigue syndrome”—a topic to which he assigned a full-time reporter, Neenyah Ostrom—was laudable. These disorders remain too much alike to arbitrarily submerge one in favor of the other, as the government has done without blinking for thirty years. Ortleb took considerable risks to profitability by pursuing every avenue of investigation on these matters. Yet, as much as Ortleb was criticized, the Native was also a “must read” of its time. When I was reporting my own book on the latter disease, I frequently spied the Native on the desks of high level scientists at the National Institutes of Health. As much as he made them uncomfortable, everyone in the AIDS research establishment wanted to know what Ortleb was going to report next. Ortleb’s caustic humor and piercing analysis of what he has dubbed “political epidemiology,” and “homodemiology” by the Centers for Disease Control alone makes Truth to Power worth the read. But the history he recounts here is crucial reading for anyone who missed the Native in its heyday or who didn’t “get it” the first time around. Given the recent rise of infectious disease alarms around the world, Truth to Power is, additionally, remarkably timely for those who seek to understand what drives the American public health establishment in times of crises. A rollicking, fascinating and important memoir.”
—Hillary Johnson, author of Osler's Web, Inside the Labyrinth of the Chronic Fatigue Syndrome Epidemic

Truth to Power is now available now on Kindle.

Saturday, March 18, 2017

Wednesday, March 15, 2017

Is HHV-8 a pig virus?

Yuan Chang and Patrick Moore win prize for the discovery of two cancer viruses

https://www.eurekalert.org/pub_releases/2017-03/guf-yca031417.php


Are infected pigs the viral source of HHV-8 and Kaposi's Sarcoma in Sardinia? Is a ASFV-related HHV-8 Kaposi's Sarcoma epidemic possible in Russia where ASFV is spreading?

The world's highest incidence of Kaposi's sarcoma occurs in Sardinia (Reference) Is it possible that it is due to the fact that African Swine Fever Virus is endemic on the island? (Reference) One study suggests that the incidence of K.S. in northern Sardinia is highest in a countryside area where people have contact with animals. (Reference) Given the high prevalence of HHV-8,--the so-called K.S. herpes virus--in Sardinia (Reference) is it at all possible that HHV-8 may have been misclassified and actually is a human-adapted form of African Swine Fever Virus? (ASFV has been at least visually mistaken for another herpes virus, CMV, in the past.)
A number of experiments could be conducted to explore this hypothesis. In addition to a direct comparison of ASFV and HHV-8, pigs with African Swine Fever Virus could be tested for sequences of HHV-8. People with Kaposi's sarcoma could be tested for sequences of African Swine Fever, including new Asfaviridae sequences recently discovered. (Reference) A comparison of the K.S. lesions in humans and ASFV lesions in pigs might be in order.
Given that African Swine Fever is currently spreading in Russia and is now threatening Europe and China, (Reference) it would be useful to know whether people who are exposed to pigs with ASFV are at increased risk for HHV-8, Kaposi's sarcoma and the other pathologies associated with HHV-8. A study in sub-Saharan Africa where ASFV is endemic and HHV-8 is also endemic (Reference) might be useful. And areas of Russia where ASFV is spreading could be monitored closely for any signs of an increase of K.S. or HHV-8 infection and HHV-8 related pathologies.
HHV-8 is an emerging health problem. HHV-8-associated K.S. is a significant problem in AIDS patients. It may also be the key to Chronic Fatigue Syndrome. HHV-8 has been found in the cerebrospinal fluid of 50% of Chronic Fatigue Syndrome patients. (Reference) HHV-8 has been linked to type 2 diabetes. (Reference) HHV-8 has been detected in B-cells in Castleman's disease and primary effusion lymphoma. (Reference).
If HHV-8 is a form of ASFV, it is possible that pigs might constitute a useful animal model for the study of possible treatments for K.S. and other pathologies associated with HHV-8. And if there is any relationship between ASFV and HHV-8, people may have to be warned to take special precautions around pigs in areas where there are ASFV outbreaks. And countries where undercooked pork is consumed (like Ukraine where salo is a staple) may need to alert the public to cook all pork products thoroughly during ASFV epidemics.

Is the HHV-6/AIDS cover-up causing an Alzheimer's epidemic?

Decreased HHV-6 IgG in Alzheimer's Disease.

"Whether HHV-6 is a factor in AD remains to be elucidated in future studies."

https://www.ncbi.nlm.nih.gov/pubmed/?term=westman+2017+hhv-6


You can help support HHV-6 University by purchasing a copy of the history of the HHV-6 cover-up, Truth to Power, now available on Amazon. Click here.

Will mouse model prove HHV-6 is the real AIDS virus?

A murine herpesvirus closely related to ubiquitous human herpesviruses causes T-cell depletion.

https://www.ncbi.nlm.nih.gov/pubmed/28179532




You can help support HHV-6 University by purchasing a copy of the history of the HHV-6 cover-up, Truth to Power, now available on Amazon. Click here.

Thursday, March 09, 2017

African Swine Fever in humans:

"The disease causes lethality of pigs in almost 100%, resulting in damage not only to vascular cells, which leads to extensive hemorrhage, but also the cells of the immune system. It is possible that the virus of African swine fever can suppress the immunity of even a human. Certainly not as pronounced as HIV, but still."


http://en.surgeon-live.com/content_svinaya-chuma-opasna-dlya-cheloveka.htm

Does Pirbright know that African Swine Fever Virus can infect people?

Scientists join forces to halt the spread of African swine fever in Europe

https://www.pirbright.ac.uk/news/2017/03/scientists-join-forces-halt-spread-african-swine-fever-europe


Russian Scientist: ASF could become a human health risk


"The African swine fever (ASF) virus, may in the future become dangerous for humans, according to the head of the Russian Epidemiology Service, Chief State Sanitary Doctor Gennady Onishchenko, at the press-conference in St. Petersburg. According to him almost all viruses from time to time go through mutation processes which can give them some additional functions."

 http://www.pigprogress.net/Health-Diseases/Outbreaks/2013/7/ASF-could-become-a-human-health-risk-1308047W/

 

 



Background on African Swine Fever Virus as a human pathogen:

"African Swine fever is an endemic disease in sub-Saharan Africa and many other parts of the developing world. It is caused by the African Swine virus that primarily replicates in macrophages and monocytes leading to the impairment of the structure and function of the immune system of the infected organisms. Until now the African Swine epidemic continues to spread despite all efforts to contain it. Thus, there is an objective need for effective, safe and affordable preventive and therapeutic approaches, in particular for effective vaccines, to control and eventually eradicate this disease. Since the characteristic feature of the African Swine virus is to impair the immune system and to cause immune deficiencies in its hosts the development of vaccines and other therapeutic approaches against the African Swine virus has implications for other immune deficiencies or diseases. Several other viruses are also known to cause immunodeficiency-like syndromes in humans, including cytomegalovirus, Epstein Barr Virus and others. Moreover, a series of cases of so-called "idiopathic" immunodeficiencies have been documented that display CD4+T-lymphocytopenia with opportunistic infections, but show no evidence of HIV infection. Since antibodies for the African Swine virus have been detected in humans, the possibility of human infection with the African Swine virus exists and may thus far have escaped any systematic screening. Thus, any preventive and therapeutic approach to African Swine fever can have far-reaching implications to control immune deficiency conditions in humans."http://www.faqs.org/patents/app/20080207875

Detection of Novel Sequences Related to African Swine Fever Virus in Human Serum and Sewage.


Loh J, Zhao G, Presti RM, Holtz LR, Finkbeiner SR, Droit L, Villasana Z, Todd C, Pipas JM, Calgua B, Girones R, Wang D, Virgin HW.

Departments of Pathology & Immunology and Molecular Microbiology, Department of Medicine and Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri; Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Microbiology, Faculty of Biology, University of Barcelona, Barcelona, Spain.

"The family Asfarviridae contains only a single virus species, African swine fever virus (ASFV). ASFV is a viral agent with significant economic impact due to its devastating effects on populations of domesticated pigs during outbreaks, but has not been reported to infect humans. We report here the discovery of novel viral sequences in human serum and sewage which are clearly related to the Asfarvirus family, but highly divergent from ASFV. Detection of these sequences suggests that greater genetic diversity may exist among Asfarviruses than previously thought, and raises the possibility that human infection by Asfarviruses may occur."
http://www.ncbi.nlm.nih.gov/pubmed/19812170?dopt=Abstract

African Swine Fever Virus (Asfarviridae) sequences found in people with febrile illnesses

Abstract
Virus Identification in Unknown Tropical Febrile Illness Cases Using Deep Sequencing
Dengue virus is an emerging infectious agent that infects an estimated 50–100 million people annually worldwide, yet current diagnostic practices cannot detect an etiologic pathogen in ∼40% of dengue-like illnesses. Metagenomic approaches to pathogen detection, such as viral microarrays and deep sequencing, are promising tools to address emerging and non-diagnosable disease challenges. In this study, we used the Virochip microarray and deep sequencing to characterize the spectrum of viruses present in human sera from 123 Nicaraguan patients presenting with dengue-like symptoms but testing negative for dengue virus. We utilized a barcoding strategy to simultaneously deep sequence multiple serum specimens, generating on average over 1 million reads per sample. We then implemented a stepwise bioinformatic filtering pipeline to remove the majority of human and low-quality sequences to improve the speed and accuracy of subsequent unbiased database searches. By deep sequencing, we were able to detect virus sequence in 37% (45/123) of previously negative cases. These included 13 cases with Human Herpesvirus 6 sequences. Other samples contained sequences with similarity to sequences from viruses in the Herpesviridae, Flaviviridae, Circoviridae, Anelloviridae, Asfarviridae, and Parvoviridae families. In some cases, the putative viral sequences were virtually identical to known viruses, and in others they diverged, suggesting that they may derive from novel viruses. These results demonstrate the utility of unbiased metagenomic approaches in the detection of known and divergent viruses in the study of tropical febrile illness.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3274504/

Detection of African swine fever virus-like sequences in ponds in the Mississippi Delta through metagenomic sequencing

" . .. further study is needed to characterize their potential risks to both public health and agricultural development."

http://link.springer.com/article/10.1007%2Fs11262-013-0878-2

ASF virus, adapted to grow in VERO cells, produces a strong cytopathic effect in human macrophages leading to cell destruction.

http://vir.sgmjournals.org/content/34/3/455.short

Wednesday, March 08, 2017

Tuesday, March 07, 2017

How Russia could take the lead in HHV-6 research.

Scientists in Russia can help advance the field of HHV-6 research by answering these questions:

1. Is HHV-6 the real AIDS virus?

2. Does HHV-6 cause a Superantigen disease by inducing HERV-K18?

3. Are we in the middle of an HHV-6 epidemic that involves Chronic Fatigue Syndrome and dozens of other disease manifestations?

4. Is HHV-6 really a pig virus?

5. Are pigs infected with a form of HHV-6?

6. Is HHV-8 also a pig virus?

7. Is HHV-6 really a form of African Swine Fever Virus?

8. Is HHV-8 also a  form of African Swine Fever Virus and does that explain why Sardinia has problems with both ASFV and HHV-8?

9. Is HIV really a huge fraud resulting from mistaking HERV-K18 for HIV?

10. Would pigs make the best animal model for HHV-6?

11. Would pigs also make the best animal model for HHV-8?

12. When you infect pigs with HHV-6 or HHV-8 do they develop symptoms of African Swine Fever Virus?

13. Is HHV-6 also the cause of the autism epidemic?

14. Do children with autism get better when you treat their HHV-6 infection with antivirals?






Sunday, March 05, 2017

The autism connection to AIDS:

Why HIV is probably not the cause of AIDS

By Etienne de Harven M.D.

Etienne de Harven M.D. is Emeritus Professor of Pathology, University of Toronto. He worked in electron microscopy primarily on the ultrastructure of retroviruses throughout his professional career of 25 years at the Sloan Kettering Institute in New York, and 13 years at the University of Toronto.





http://www.virusmyth.com/aids/hiv/edhjaps.pdf





Charles Ortleb’s Truth to Power takes you inside the New York Native, one of the most unique and consequential newspapers of the twentieth century. Shortly after starting his small gay New York City newspaper in late 1980, one of the biggest scientific and political stories of our time fell into his lap in the form of the AIDS and Chronic Fatigue Syndrome epidemic. What he did with that story has secured his newspaper’s place in history. Under his guidance, a succession of intrepid journalists did some of their greatest work uncovering the crucial facts about the labyrinthine epidemic.

Ortleb made the decision to follow the facts wherever they led. His team of uncompromising investigative reporters inevitably stepped on the toes of the most powerful people in the medical and political establishment. Perhaps not surprisingly, the latter fought back by seeking to discredit the New York Native and even, in time, close its doors. But Ortleb stood his ground for as long as possible and as a result the world now can have a clear understanding of the relationship of AIDS, Chronic Fatigue Syndrome, and HHV-6, the transmissible virus that now threatens everyone on this planet.

Anyone who has wondered why the medical establishment will not tell the truth about the Chronic Fatigue Syndrome epidemic will find the disturbing answer in Truth to Power.

What makes Ortleb so unusual is that not only did he have the natural instincts of a journalist, editor and publisher, but he was also a poet, a fiction writer and a budding political philosopher. Truth to Power is not just a compelling work of journalism and history, but also a major contribution to the intellectual life of our time.

“Charles Ortleb, as editor-in-chief and publisher of the New York Native, was and remains the Izzy Stone of science reporting. He was fearless in his pursuit of the origins of the AIDS epidemic and the government’s response in the 1980s. When his newspaper began to diverge from the dogmatic mainstream, however, he was ostracized by the very people he was seeking to inform. In addition, his laser-like focus in the Native on the simultaneous emergence of so-called “chronic fatigue syndrome”—a topic to which he assigned a full-time reporter, Neenyah Ostrom—was laudable. These disorders remain too much alike to arbitrarily submerge one in favor of the other, as the government has done without blinking for thirty years. Ortleb took considerable risks to profitability by pursuing every avenue of investigation on these matters. Yet, as much as Ortleb was criticized, the Native was also a “must read” of its time. When I was reporting my own book on the latter disease, I frequently spied the Native on the desks of high level scientists at the National Institutes of Health. As much as he made them uncomfortable, everyone in the AIDS research establishment wanted to know what Ortleb was going to report next. Ortleb’s caustic humor and piercing analysis of what he has dubbed “political epidemiology,” and “homodemiology” by the Centers for Disease Control alone makes Truth to Power worth the read. But the history he recounts here is crucial reading for anyone who missed the Native in its heyday or who didn’t “get it” the first time around. Given the recent rise of infectious disease alarms around the world, Truth to Power is, additionally, remarkably timely for those who seek to understand what drives the American public health establishment in times of crises. A rollicking, fascinating and important memoir.”
—Hillary Johnson, author of Osler's Web, Inside the Labyrinth of the Chronic Fatigue Syndrome Epidemic

Truth to Power is now available now on Amazon.

What Does Truvada Reveal about the Relationship of AIDS and Chronic Fatigue Syndrome?


Truvada and Chronic fatigue syndrome - from FDA reports

http://www.ehealthme.com/ds/truvada/chronic%20fatigue%20syndrome/


Chronic fatigue syndrome after PEP treatment?

http://helpline.aidsvancouver.org/what-we-do/helpline/online/chronic-fatigue-syndrome-after-pep-treatment




Charles Ortleb’s Truth to Power takes you inside the New York Native, one of the most unique and consequential newspapers of the twentieth century. Shortly after starting his small gay New York City newspaper in late 1980, one of the biggest scientific and political stories of our time fell into his lap in the form of the AIDS and Chronic Fatigue Syndrome epidemic. What he did with that story has secured his newspaper’s place in history. Under his guidance, a succession of intrepid journalists did some of their greatest work uncovering the crucial facts about the labyrinthine epidemic.

Ortleb made the decision to follow the facts wherever they led. His team of uncompromising investigative reporters inevitably stepped on the toes of the most powerful people in the medical and political establishment. Perhaps not surprisingly, the latter fought back by seeking to discredit the New York Native and even, in time, close its doors. But Ortleb stood his ground for as long as possible and as a result the world now can have a clear understanding of the relationship of AIDS, Chronic Fatigue Syndrome, and HHV-6, the transmissible virus that now threatens everyone on this planet.

Anyone who has wondered why the medical establishment will not tell the truth about the Chronic Fatigue Syndrome epidemic will find the disturbing answer in Truth to Power.

What makes Ortleb so unusual is that not only did he have the natural instincts of a journalist, editor and publisher, but he was also a poet, a fiction writer and a budding political philosopher. Truth to Power is not just a compelling work of journalism and history, but also a major contribution to the intellectual life of our time.

“Charles Ortleb, as editor-in-chief and publisher of the New York Native, was and remains the Izzy Stone of science reporting. He was fearless in his pursuit of the origins of the AIDS epidemic and the government’s response in the 1980s. When his newspaper began to diverge from the dogmatic mainstream, however, he was ostracized by the very people he was seeking to inform. In addition, his laser-like focus in the Native on the simultaneous emergence of so-called “chronic fatigue syndrome”—a topic to which he assigned a full-time reporter, Neenyah Ostrom—was laudable. These disorders remain too much alike to arbitrarily submerge one in favor of the other, as the government has done without blinking for thirty years. Ortleb took considerable risks to profitability by pursuing every avenue of investigation on these matters. Yet, as much as Ortleb was criticized, the Native was also a “must read” of its time. When I was reporting my own book on the latter disease, I frequently spied the Native on the desks of high level scientists at the National Institutes of Health. As much as he made them uncomfortable, everyone in the AIDS research establishment wanted to know what Ortleb was going to report next. Ortleb’s caustic humor and piercing analysis of what he has dubbed “political epidemiology,” and “homodemiology” by the Centers for Disease Control alone makes Truth to Power worth the read. But the history he recounts here is crucial reading for anyone who missed the Native in its heyday or who didn’t “get it” the first time around. Given the recent rise of infectious disease alarms around the world, Truth to Power is, additionally, remarkably timely for those who seek to understand what drives the American public health establishment in times of crises. A rollicking, fascinating and important memoir.”
—Hillary Johnson, author of Osler's Web, Inside the Labyrinth of the Chronic Fatigue Syndrome Epidemic

Truth to Power is now available now on Kindle.

complete book list



newsletter

CFS Book 1 audio

Patient Zero

Intro to Patient Zero

Book previews

Book Previews 2

Book previews 3

Book previews 4

Ourbooks on Amazon

ad for cfs book

New York Native Chapters

New York Native Chapters 2

New York Native Chapters 3

Final New York Native Chapter

Audible CFS book

Popular Posts in the Last 30 Days

You can support us by listening to these songs by Charles Ortleb on Spotify.