Lipkin's anellovirus findings in CFS may just be more evidence that AIDS and CFS are part of the same epidemic
Lipkin, Anellovirus and CFS:
The Anellovirus was found in 75% of ME cases and evidence of Retroviruses were found in 85% of cases, in research conducted by Dr. Hornig and Dr. Lipkins study in September 2013.
http://www.cfs-ireland.com/diag/2.htm
Read more: The Lipkin Study, The Vagus Nerve Infection Hypothesis and HHV-6: Kristin Loomis of the HHV-6 Foundation Talks – Pt. I http://www.cortjohnson.org/blog/2014/01/09/lipkin-study-vagus-nerve-hhv-6-loomis-hhv-6-foundation/
"We compared the plasma viromes of HIV-infected subjects with low versus high CD4+ T cell counts from the United States and Uganda by using deep sequencing and detected HIV, hepatitis C virus, hepatitis B virus, GB virus C, anellovirus, and human endogenous retrovirus (HERV) reads. An increase in the proportion of reads for anelloviruses, a family of highly prevalent and genetically diverse human viruses, was seen in subjects with AIDS from both countries. The proportion of endogenous human retrovirus reads was increased in AIDS subjects from Uganda but not the United States. Progression to AIDS is therefore associated with changes in the plasma concentration of commensal viruses."
http://jvi.asm.org/content/87/19/10912.full
Anellovirus and Pigs
Anelloviruses are small, single-stranded, circular DNA viruses that infect a wide range of animal species, from humans to domestic animals, including pigs (13, 34). Most recently, all human and other animal anelloviruses have been assigned to a newly established family, Anelloviridae, that includes nine genera (3).
Human and porcine anelloviruses have the same genomic structure, which consists of at least four presumed open readingframes (ORFs), ORF1, ORF2, ORF1/1, and ORF2/2, as well as a short stretch with high GC content in the untranslated region (UTR) (5, 16, 36, 38).
http://jvi.asm.org/content/86/11/6042.full
The Anellovirus was found in 75% of ME cases and evidence of Retroviruses were found in 85% of cases, in research conducted by Dr. Hornig and Dr. Lipkins study in September 2013.
http://www.cfs-ireland.com/diag/2.htm
Anellovirus is found in
a significant percentage of healthy controls as well. If Lipkin found a
much higher viral load in ME/CFS patients this could be a very
important finding because the Stanford study suggests that the
anellovirus load is a good proxy for overall immune status.
Read more: The Lipkin Study, The Vagus Nerve Infection Hypothesis and HHV-6: Kristin Loomis of the HHV-6 Foundation Talks – Pt. I http://www.cortjohnson.org/blog/2014/01/09/lipkin-study-vagus-nerve-hhv-6-loomis-hhv-6-foundation/
Read more: The Lipkin Study, The Vagus Nerve Infection Hypothesis and HHV-6: Kristin Loomis of the HHV-6 Foundation Talks – Pt. I http://www.cortjohnson.org/blog/2014/01/09/lipkin-study-vagus-nerve-hhv-6-loomis-hhv-6-foundation/
Anellovirus is found in
a significant percentage of healthy controls as well. If Lipkin found a
much higher viral load in ME/CFS patients this could be a very
important finding because the Stanford study suggests that the
anellovirus load is a good proxy for overall immune status.
Read more: The Lipkin Study, The Vagus Nerve Infection Hypothesis and HHV-6: Kristin Loomis of the HHV-6 Foundation Talks – Pt. I http://www.cortjohnson.org/blog/2014/01/09/lipkin-study-vagus-nerve-hhv-6-loomis-hhv-6-foundation/
Anellovirus is found in
a significant percentage of healthy controls as well. If Lipkin found a
much higher viral load in ME/CFS patients this could be a very
important finding because the Stanford study suggests that the
anellovirus load is a good proxy for overall immune status.Read more: The Lipkin Study, The Vagus Nerve Infection Hypothesis and HHV-6: Kristin Loomis of the HHV-6 Foundation Talks – Pt. I http://www.cortjohnson.org/blog/2014/01/09/lipkin-study-vagus-nerve-hhv-6-loomis-hhv-6-foundation/
Read more: The Lipkin Study, The Vagus Nerve Infection Hypothesis and HHV-6: Kristin Loomis of the HHV-6 Foundation Talks – Pt. I http://www.cortjohnson.org/blog/2014/01/09/lipkin-study-vagus-nerve-hhv-6-loomis-hhv-6-foundation/
Anellovirus is found in
a significant percentage of healthy controls as well. If Lipkin found a
much higher viral load in ME/CFS patients this could be a very
important finding because the Stanford study suggests that the
anellovirus load is a good proxy for overall immune status.
Read more: The Lipkin Study, The Vagus Nerve Infection Hypothesis and HHV-6: Kristin Loomis of the HHV-6 Foundation Talks – Pt. I http://www.cortjohnson.org/blog/2014/01/09/lipkin-study-vagus-nerve-hhv-6-loomis-hhv-6-foundation/
Anellovirus and AIDS:Read more: The Lipkin Study, The Vagus Nerve Infection Hypothesis and HHV-6: Kristin Loomis of the HHV-6 Foundation Talks – Pt. I http://www.cortjohnson.org/blog/2014/01/09/lipkin-study-vagus-nerve-hhv-6-loomis-hhv-6-foundation/
"We compared the plasma viromes of HIV-infected subjects with low versus high CD4+ T cell counts from the United States and Uganda by using deep sequencing and detected HIV, hepatitis C virus, hepatitis B virus, GB virus C, anellovirus, and human endogenous retrovirus (HERV) reads. An increase in the proportion of reads for anelloviruses, a family of highly prevalent and genetically diverse human viruses, was seen in subjects with AIDS from both countries. The proportion of endogenous human retrovirus reads was increased in AIDS subjects from Uganda but not the United States. Progression to AIDS is therefore associated with changes in the plasma concentration of commensal viruses."
http://jvi.asm.org/content/87/19/10912.full
Anellovirus and Pigs
Anelloviruses are small, single-stranded, circular DNA viruses that infect a wide range of animal species, from humans to domestic animals, including pigs (13, 34). Most recently, all human and other animal anelloviruses have been assigned to a newly established family, Anelloviridae, that includes nine genera (3).
Human and porcine anelloviruses have the same genomic structure, which consists of at least four presumed open readingframes (ORFs), ORF1, ORF2, ORF1/1, and ORF2/2, as well as a short stretch with high GC content in the untranslated region (UTR) (5, 16, 36, 38).
http://jvi.asm.org/content/86/11/6042.full
