Book previews

Saturday, January 05, 2019

Everything you wanted to know about Kaposi’s Sarcoma in Chronic Fatigue Syndrome patients and the growing CFS epidemic of HHV-8



"Persons infected with KSHV can asymptomatically shed the virus. It is advised to practice safe sex with infected individuals and curtail activities where saliva might be shared during sexual activity."


http://www.herpes.com/hhv-8.html




This is what oral Kaposi's Sarcoma looks like.




Source: https://doctorspiller.com/kaposis-sarcoma/

Compare it to these crimson crescent lesions in the mouths of Chronic Fatigue Syndrome patients.



"Burke A. Cunha, MD, discovered what he called crimson crescents in the mouths of 80% of his CFS patients. After the word got out, Cunha received calls from other parts of the country. Physicians began telling him that they also were finding the crimson crescents in their patients once they looked for them."

https://www.prohealth.com/library/crimson-crescents-facilitate-chronic-fatigue-syndrome-cfs-diagnosis-11266




Chronic Fatigue Syndrome patients may have undiagnosed internal Kaposi's Sarcoma. Susan Levine found HHV-8, the Kaposi's Sarcoma virus, in half of CFS patients she looked at.

Prevalence in the Cerebrospinal Fluid of the Following Infectious Agents in a Cohort of 12 CFS Subjects


Susan Levine

Published online: 04 Dec 2011



Over the last decade a wide variety of infectious agents has been associated with the chronic fatigue syndrome (CFS) as potential etiologies for this disorder by researchers from all over the world. Many of these agents are neurotrophic and have been linked previously to other diseases involving the central nervous system (CNS). Human herpes virus-6 (HHV-6), especially the B variant, has been found in autopsy specimens of patients who suffered from multiple sclerosis. Because patients with CFS manifest a wide range of symptoms involving the CNS as shown by abnormalities on brain MRIs, SPECT scans of the brain and results of tilt table testing we sought to determine the prevalence of HHV-6, HHV-8, Epstein-Barr virus (EBV), cytomegalovirus (CMV), Mycoplasma species, Chlamydia species, and Coxsackie virus in the spinal fluid of a group of 12 patients with CFS. Although we intended to search mainly for evidence of actively replicating HHV-6, a virus that has been associated by several researchers with this disorder, we found evidence of HHV-8, Chlamydia species, CMV and Coxsackie virus in 6/12 samples. Attempts were made to correlate the clinical presentations of each of these patients, especially the neurological exams and results of objective testing of the CNS, with the particular infectious agent isolated. It was also surprising to obtain such a relatively high yield of infectious agents on cell free specimens of spinal fluid that had not been centrifuged. Future research in spinal fluid analysis, in addition to testing tissue samples by polymerase chain reaction (PCR) and other direct viral isolation techniques will be important in characterizing subpopulations of CFS patients, especially those with involvement of the CNS.

https://www.tandfonline.com/doi/abs/10.1300/J092v09n01_05








Everything you wanted to know about Kaposi’s Sarcoma in Chronic Fatigue Syndrome patients and the growing CFS epidemic of HHV-8, one of the two or three viruses that may be causing Kaposi’s Sarcoma.







Excerpted from The Chronic Fatigue Syndrome Epidemic Cover-up, a bestseller on Amazon.



     Neenyah Ostrom began one of my favorite series of articles in the same issue. Titled “The Color Purple,” Ostrom reported, “Burke Cunha, M.D. who is chief of infectious disease at Winthrop-University Hospital (Mineola, Long Island), has described what he calls ‘crimson crescents’ that appear in the throats of more than 80 percent of chronic fatigue syndrome (CFS) patients. Cunha describes the crescents not only as ‘crimson,’ but ‘purplish.’ The reddish-purplish regions found in CFS patients’ throats sounded quite similar to KS (Kaposi’s sarcoma) in the throat, commented an ‘AIDS’ doctor [who wished to remain anonymous] to whom they were described. Is it possible that the crimson crescents observed in the throats of CFS patients are actually a type of KS?”      Ostrom raised the possibility that the lesions in the throats of CFS patients connected them to the theory that Florida researchers held about KS being the unrecognized but unifying central pathological event AIDS. As I previously reported, the Florida team, headed by Dr. George Hensley, had turned the AIDS paradigm upside down, by finding KS in nearly 100% of AIDS patients, when they explored the internal organs closely during autopsies of AIDS patients. Their fascinating work suggested that KS preceded AIDS and caused more of the immune problem in AIDS than previously thought.

     Basically, Ostrom was asking if the KS-like lesions, in the tonsils of [CFS]patients, were an indication that some kind of unrecognized indolent KS was present internally, something that physicians would not even be thinking about because of the conceptual wall that socially hostile epidemiology had built between AIDS and chronic fatigue syndrome. And the CFS patients were not particularly interested in finding out if they shared KS with AIDS patients.

    Ostrom went even further, in the July 20 issue, and speculated that the dramatic digestive problems in chronic fatigue syndrome were actually the result of the unrecognized chronic or slowly progressive KS in the CFS patients’ digestive tracts. Ostrom noted that Dr. Carol Jessop, who was talking to a group of patients at a chronic fatigue syndrome conference, said, “Almost all patients would say to me, ‘I was totally well until I got this [chronic fatigue syndrome],’ and yet, when I took their past medical histories, I found it wasn’t quite true. Now these aren’t disastrous problems. In fact, if they had gone to their physicians for any of these problems such as irritable bowel, diarrhea and constipation, abdominal cramping, bloating, flatulence, chronic constipation, heartburn, etc., their physician would probably just say, ‘Oh, take this’ and that would be it. So we as physicians didn’t relate to our patients that this was a problem, so they considered themselves to be totally healthy. Yet, if you look at the numbers, 89 percent of the [chronic fatigue syndrome] patients had irritable bowel syndrome, diarrhea alternating with constipation, and abdominal cramping pain episodically. Another 80 percent complained of constant gas, bloating and flatulence. It’s amazing that we can all meet in this room together.”       Ostrom wondered if “Jessop may have uncovered a fallacy in the prevailing wisdom of chronic fatigue syndrome: that it begins as a respiratory, flu-like illness. Instead, as she points out, it may be a digestive tract disturbance. Jessop’s statistic—that more than 80 percent of CFS patients complain of irritable bowel syndrome, abdominal pain, gas, bloating, etc.—corresponds to the more than 80 percent of CFS patients who exhibit a red-to-purplish crescent-shaped lesion in their throats. (Helot, Paul, in the New York Times Long Island edition, January 14, 1992) . . . What if the digestive problems described by the CFS patients are actually caused by KS in the gastrointestinal tract? According to the AIDS Treatment News, ‘The most common HIV-related causes of gastric symptoms include KS, lymphoma, and CMV [cytomegalovirus].’ And while KS is unusual in the esophagus, it ‘may occasionally be found there.’ KS also can cause colitis and diarrhea . . . in people with AIDS.” Ostrom noted, “Gastrointestinal symptoms, it is realized in retrospect, were among the first signs of the ‘AIDS’ epidemic; and, it now seems, were also among the first symptoms seen in the CFS epidemic. That observation raises what should be a relatively simple question to answer: Are the gastrointestinal symptoms in both patient populations caused, in part, by undetected KS?”





Excerpted from The Chronic Fatigue Syndrome Epidemic Cover-up, a bestseller on Amazon.







Important information about the Kaposi’s Sarcoma problem in Chronic Fatigue Syndrome

Whatever happened to the concern about controlling the Kaposi's Sarcoma Virus? What about all the infected Chronic Fatigue Syndrome patients?


Is Kaposi's Sarcoma responsible for the digestive disorders in Chronic Fatigue Syndrome?


HHV-8 is a Kaposi's Sarcoma cancer virus in many AIDS and Chronic Fatigue Syndrome patients and is spread by kissing but the CDC couldn't care less.


Company founded by Robert Gallo suggests 65% of gay men are infected with Kaposi's Sarcoma virus.


Coagulation issues may link Chronic Fatigue Syndrome, Kaposi's Sarcoma, and AIDS


Should Chronic Fatigue Syndrome be added to the spectrum of Kaposi's Sarcoma-Associated Herpesvirus, or Human Herpesvirus 8, Diseases?


Why Susan Levine may have done the world's most important research on Chronic Fatigue Syndrome.


Does HHV-8 viral load raise questions about the legitimacy of HIV viral load?


Can Chronic Fatigue Syndrome patients with internal Kaposi's Sarcoma pass it on to their partners?


Can most of the symptoms of Chronic Fatigue Syndrome described by Paul Cheney be attributed to internal Kaposi's Sarcoma?


Is Chronic Fatigue Syndrome Associated Kaposi's Sarcoma  (CFSKS) a diagnosis all doctors should become aware of?


Stanford University and Open Medicine Foundation should have a conference on diagnosing Kaposi's Sarcoma in Chronic Fatigue Syndrome.


Why are doctors not looking for Kaposi's Sarcoma in Chronic Fatigue Syndrome patients?


If Chronic Fatigue Syndrome involves HHV-8 and Kaposi's Sarcoma, scientists will have to ask if it came from pigs.


Does the Red Blood Cell Deformability Issue Link Chronic Fatigue Syndrome to Kaposi's Sarcoma and AIDS?


Will the Montoya cytokine study show that Chronic Fatigue Syndrome is Kaposi's Sarcoma Inflammatory Syndrome?


Is Chronic Fatigue Syndrome a Kaposi's Sarcoma inflammatory cytokine syndrome?


How Kaposi's Sarcoma almost undermined the HIV theory of AIDS


How did 50% of Chronic Fatigue Syndrome patients become infected with a Kaposi’s Sarcoma cancer virus?


Has the moment finally come to address the issue of Kaposi's Sarcoma in Chronic Fatigue Syndrome?


Oral Kaposi's Sarcoma looks like the Crimson Crescents in Chronic Fatigue Syndrome patients.


Were oral crimson crescents the first obvious sign of Kaposi's Sarcoma in Chronic Fatigue Syndrome patients?


Did Paul Cheney ever consider the possibility that Chronic Fatigue Syndrome patients have internal Kaposi's Sarcoma?


Is the red blood cell deformability issue another clue that Chronic Fatigue Syndrome is also a Kaposi's Sarcoma Syndrome?


Why is nobody warned about exposure to HHV-8, the Kaposi's Sarcoma virus that even patients with Chronic Fatigue Syndrome are sometimes infected with?


Do petechiae in Chronic Fatigue Syndrome connect it to Kaposi's Sarcoma, HHV-8, and AIDS?


Whatever is causing Kaposi's Sarcoma may be the real cause of Chronic Fatigue Syndrome and AIDS.


A massive epidemic of Kaposi's Sarcoma may be coming.


When Kaposi's Sarcoma almost turned AIDS upside down.


Human herpesvirus 6 activates lytic cycle replication of Kaposi's sarcoma-associated herpesvirus.


All AIDS patients have some form of Kaposi's Sarcoma in this study. Is the same true for Chronic Fatigue Syndrome?


Crimson crescents may suggest that all Chronic Fatigue Syndrome patients have Kaposi's Sarcoma.


Do all Chronic Fatigue Syndrome patients have an indolent form of Kaposi's Sarcoma?


Are these marks on the skin a sign of Kaposi’s Sarcoma in Chronic Fatigue Syndrome?


On autopsy, do the inflamed ganglia of Chronic Fatigue Syndrome patients resemble Kaposi's Sarcoma?


What people don't know about Kaposi's Sarcoma in Chronic Fatigue Syndrome and AIDS.


Do all Chronic Fatigue Syndrome patients show internal Kaposi's Sarcoma upon autopsy?




Decades ago, a New York newspaper sounded the alarm about Kaposi’s Sarcoma in Chronic Fatigue Syndrome. The book about that newspaper is now a must-read bestseller on Amazon. Purchase a hardcover, paperback, or Kindle version here.






Gay and bisexual men are at high risk for infection with up to 60% of gay men found to be infected with the Kaposi's Sarcoma Virus in some studies




Biotrin Human Herpes Virus 8 Products
Frequently Asked Questions
1. What is HHV 8?
Human Herpes Virus 8 (HHV 8) is also known as Kaposi’s sarcoma associated herpes virus or KSHV. It is the causative agent of Kaposi’s Sarcoma (KS), a tumour. It was first identified in 1994 when HHV 8 DNA was isolated from KS lesions. The Virus has also been associated with other lymphoproliferative disorders such as Burkitt’s lymphoma, Castleman’s disease (form of lymph node enlargement), body cavity lymphoma, non-hodgkin’s lymphoma and multiple myeloma.
Infection with this virus is thought to be life-long, but a healthy immune system will keep the virus in check. KS occurs when someone who has been infected with KSHV becomes immunocompromised due to AIDS, old age or medical treatment.
2. How prevalent is HHV 8?
KSHV is an uncommon infection in industrialised countries such as North America/North Europe, where less than 2% of the general population is infected with the virus.

The virus is more frequent is some Mediterranean countries such as Italy and Greece (4-35%), while it is widespread in Africa (30-60%).
The burden of KS is high in Africa, where KS accounts for almost half of all reported cancers in certain countries including Uganda.

3. What groups are most at risk to this virus?
African populations are at risk to this virus due to the high prevalence of the virus. It is thought that infection in Africa is spread through non-sexual routes that remain poorly understood.
Gay and bisexual men are at high risk for infection with up to 60% of gay men found to be infected in some studies. Among gay men, the incidence increases with the number of sex partners. The exact reasons why gay men are at high risk for infection compared to heterosexuals remains unknown, although it has been suggested that men in general may be more susceptible to the virus and therefore more likely to transmit it to male sex partners.
HHV 8 infection is also of particular concern to individuals receiving organ transplants. Not only is there a risk of transmitting the virus from the donated organ, but recipients are immunosuppressed to avoid organ rejection and are at high risk for developing KS if they are infected. Some studies found that up to 50% of transplant recipients who are infected with HHV-6 develop KS. This can cause loss of the donated organ and be life-threatening.
4. What is Kaposi’s sarcoma (KS)?
It is a tumour caused by the Human Herpes Virus 8 (HHV8) in which cancerous cells, as well as abnormally growing blood vessels, form solid KS lesions in connective tissue.
KS lesions are nodules or blotches that may be red, purple, brown, or black, usually painless but sometimes painful and swollen. They most often appear under the surface of the skin or on mucous membranes, where they are only dangerous if they cause enough swelling to obstruct circulation, breathing, or eating. They may also be found in internal organs, particularly the respiratory system or gastrointestinal system; internal lesions are most commonly seen in epidemic KS, and can cause fatal bleeding.
Kaposi's sarcoma occurs when someone who has been infected with KSHV becomes immunocompromised due to AIDS, old age or medical treatment.

5. How is HHV 8 transmitted?
In African countries, infection is commonly spread through non-sexual routes that remain poorly understood. Young children can be infected (although direct transmission from mothers to their children during pregnancy is uncommon), and rates of infection can continue to increase throughout adulthood. A form of Kaposi's sarcoma occurring in young African children due to this infection is almost uniformly and rapidly fatal.
Infections with HHV 8 are generally asymptomatic. People infected with KSHV will asymptomatically shed the virus and caution should be used by sex partners in having unprotected sex and activities where saliva might be shared such as deep-kissing.
Unlike HIV, it is not clear whether the virus is transmitted through unprotected anal intercourse. Instead, it is likely that it is transmitted between sex partners by oral secretions (e.g. saliva).

6. How are HHV 8 infections treated?
Infection with this virus is thought to be a life-long infection, however a healthy immune system will keep the virus in check. KS or other disorders occur when someone who has been infected with HHV 8 becomes immunocompromised. The most effective treatment is treatment is of the underlying immunodeficiency.
Antiviral drugs, such as ganciclovir, that target the replication of herpesviruses such as KSHV have been used to successfully prevent development of KS, although once the tumor develops these drugs are of little use.
For patients with AIDS-KS, the most effective therapy is highly active antiretroviral therapy to reduce HIV infection. AIDS patients receiving adequate anti-HIV treatment may have up to a 90% reduction in Kaposi's sarcoma occurrence.
There is no vaccination available for this virus.


https://web.archive.org/web/20111010032706/http://www.biotrin.com/HHV8_FAQ.html

Whatever happened to the concern about controlling the Kaposi's Sarcoma Virus? What about all the infected Chronic Fatigue Syndrome patients?



"Persons infected with KSHV can asymptomatically shed the virus. It is advised to practice safe sex with infected individuals and curtail activities where saliva might be shared during sexual activity."


http://www.herpes.com/hhv-8.html




This is what oral Kaposi's Sarcoma looks like.




Source: https://doctorspiller.com/kaposis-sarcoma/

Compare it to these crimson crescent lesions in the mouths of Chronic Fatigue Syndrome patients.



"Burke A. Cunha, MD, discovered what he called crimson crescents in the mouths of 80% of his CFS patients. After the word got out, Cunha received calls from other parts of the country. Physicians began telling him that they also were finding the crimson crescents in their patients once they looked for them."

https://www.prohealth.com/library/crimson-crescents-facilitate-chronic-fatigue-syndrome-cfs-diagnosis-11266




Chronic Fatigue Syndrome patients may have undiagnosed internal Kaposi's Sarcoma. Susan Levine found HHV-8, the Kaposi's Sarcoma virus, in half of CFS patients she looked at.

Prevalence in the Cerebrospinal Fluid of the Following Infectious Agents in a Cohort of 12 CFS Subjects


Susan Levine

Published online: 04 Dec 2011



Over the last decade a wide variety of infectious agents has been associated with the chronic fatigue syndrome (CFS) as potential etiologies for this disorder by researchers from all over the world. Many of these agents are neurotrophic and have been linked previously to other diseases involving the central nervous system (CNS). Human herpes virus-6 (HHV-6), especially the B variant, has been found in autopsy specimens of patients who suffered from multiple sclerosis. Because patients with CFS manifest a wide range of symptoms involving the CNS as shown by abnormalities on brain MRIs, SPECT scans of the brain and results of tilt table testing we sought to determine the prevalence of HHV-6, HHV-8, Epstein-Barr virus (EBV), cytomegalovirus (CMV), Mycoplasma species, Chlamydia species, and Coxsackie virus in the spinal fluid of a group of 12 patients with CFS. Although we intended to search mainly for evidence of actively replicating HHV-6, a virus that has been associated by several researchers with this disorder, we found evidence of HHV-8, Chlamydia species, CMV and Coxsackie virus in 6/12 samples. Attempts were made to correlate the clinical presentations of each of these patients, especially the neurological exams and results of objective testing of the CNS, with the particular infectious agent isolated. It was also surprising to obtain such a relatively high yield of infectious agents on cell free specimens of spinal fluid that had not been centrifuged. Future research in spinal fluid analysis, in addition to testing tissue samples by polymerase chain reaction (PCR) and other direct viral isolation techniques will be important in characterizing subpopulations of CFS patients, especially those with involvement of the CNS.

https://www.tandfonline.com/doi/abs/10.1300/J092v09n01_05






Blog Archive

Popular Posts in the Last 30 Days

You can support us by listening to these songs by Charles Ortleb on Spotify.

cfs book scrib promo

Previous HHV-6 University Reports

ad for cfs book

Audible CFS book

Closing Argument Audible

African Swine Fever Novel Audible

Stonewall Audible