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Saturday, November 02, 2019

A new finding may link Chronic Fatigue Syndrome to the AIDS epidemic: Intra brainstem connectivity is impaired.

Intra brainstem connectivity is impaired in chronic fatigue syndrome

Neuroimage Clin. 2019 Oct 19;24:102045. doi:
10.1016/j.nicl.2019.102045. [Epub ahead of print]
Intra brainstem connectivity is impaired in chronic fatigue syndrome.
Barnden LR, Shan ZY, Staines DR, Marshall-Gradisnik S, Finegan K,
Ireland T, Bhuta S.


In myalgic encephalomyelitis or chronic fatigue syndrome (ME/CFS),
abnormal MRI correlations with symptom severity and autonomic measures
have suggested impaired nerve signal conduction within the brainstem.
Here we analyse fMRI correlations to directly test connectivity within
and from the brainstem. Resting and task functional MRI (fMRI) were
acquired for 45 ME/CFS (Fukuda criteria) and 27 healthy controls (HC).
We selected limited brainstem reticular activation system (RAS)
regions-of-interest (ROIs) based on previous structural MRI findings
in a different ME/CFS cohort (bilateral rostral medulla and midbrain
cuneiform nucleus), the dorsal Raphe nucleus, and two subcortical ROIs
(hippocampus subiculum and thalamus intralaminar nucleus) reported to
have rich brainstem connections. When HC and ME/CFS were analysed
separately, significant correlations were detected for both groups
during both rest and task, with stronger correlations during task than
rest. In ME/CFS, connections were absent between medulla and midbrain
nuclei, although hippocampal connections with these nuclei were
enhanced. When corresponding correlations from HC and ME/CFS were
compared, ME/CFS connectivity deficits were detected within the
brainstem between the medulla and cuneiform nucleus and between the
brainstem and hippocampus and intralaminar thalamus, but only during
task. In CFS/ME, weaker connectivity between some RAS nuclei was
associated with increased symptom severity. RAS neuron oscillatory
signals facilitate coherence in thalamo-cortical oscillations.
Brainstem RAS connectivity deficits can explain autonomic changes and
diminish cortical oscillatory coherence which can impair attention,
memory, cognitive function, sleep quality and muscle tone, all
symptoms of ME/CFS.

Structural and functional brain imaging in acute HIV

Healthcare watch: Nancy Pelosi basically tells Warren and Sanders that Medicare for all is nuts.

Human, Adult, Clown, Harlequin, Fool

Mayor Pete: “I am running to be the president who will stand amid the rubble, pick up the pieces of our divided nation and lead us to real action to do right by Americans who have waited far too long.”

Here is Mayor Pete's guide to ending the Chronic Fatigue Syndrome epidemic 

Now an audiobook!

On April 16, 1996, Congressman Jerrold Nadler spoke on the floor of Congress about his request for a General Accounting investigation into how the CDC had handled the Chronic Fatigue Syndrome epidemic. Nadler did that at the urging of Charles Ortleb, the publisher and the New York Native and his reporter Neenyah Ostrom. Ortleb and Ostrom had made the case to Nadler that Chronic Fatigue Syndrome and the virus it had been linked to, HHV-6, were serious public health issues.         
In an interview in New York Native with Neenyah Ostrom,Congressman Nadler said, "Congress can mandate research into CFS as a viral disease. Maybe it will turn out that HHV-6A is the cause of CFS; maybe it will turn out that other viruses are involved. But Congress can mandate research into CFS as a contagious, viral disease. I will certainly try to get Congress to do that as soon as possible."

Unfortunately, back in 1996, Nadler's warning to Congress and the medical establishment fell on deaf ears. But now that the Democrats have regained power in the House of Representatives, the newly prominent Congressman Nadler may finally be able to bring the Chronic Fatigue Syndrome epidemic and HHV-6 to the public's attention.

This book by Charles Ortleb, which details Neenyah Ostrom's diligent reporting on Chronic Fatigue Syndrome, is necessary reading for anyone who wants to know the whole history of an epidemic which has been hidden in plain sight. For a decade, starting in 1988, Ostrom reported on Chronic Fatigue Syndrome and the damage that the virus HHV-6 does to patients. What her reporting uncovered about the true nature of the Chronic Fatigue Syndrome epidemic will shock you. 

In The Chronic Fatigue Syndrome Epidemic Cover-up, Charles Ortleb recounts his newspaper's fascinating struggle to get the medical and political establishment to pay attention to Ostrom's pioneering investigative reporting on Chronic Fatigue Syndrome. 

By the time you finish Ortleb's stunning memoir, you will understand why the CDC has been unwilling to tell the public the truth about Chronic Fatigue Syndrome. The CDC does not want the public to know that Chronic Fatigue Syndrome is a transmissible illness linked to a virus that affects every system in the body. They have covered up the illness for so many decades that the neglected virus is totally out of control. Now it is causing a long list of other illnesses and many cancers. The CDC has put us all in danger.

Ostrom's decade of reporting on HHV-6 was recently vindicated by this statement from scientists at the University of Wurzburg: "While HHV-6 was long believed to have no negative impact on human health, scientists today increasingly suspect the virus of causing various diseases such as multiple sclerosis or chronic fatigue syndrome. Recent studies even suggest that HHV-6 might play a role in the pathogenesis of several diseases of the central nervous system such as schizophrenia, bipolar disorder, depression or Alzheimer's." 

The big question about Neenyah Ostrom and New York Native is this: How many lives would have been saved if the scientific establishment and the mainstream media had paid more attention to Neenyah Ostrom's reporting on HHV-6 and Chronic Fatigue Syndrome in New York Native?             

One day, if there is any justice in the world, the CDC and the medical establishment will apologize for not paying attention to Neenyah Ostrom's groundbreaking work on Chronic Fatigue Syndrome that Charles Ortleb published in New York Native. That would be a fitting end to one of journalism's greatest David and Goliath stories.    

Anyone who wants to help Congressman Nadler and the other members of Congress who are trying to end the suffering of millions of people with Chronic Fatigue Syndrome, needs to read The Chronic Fatigue Syndrome Epidemic Cover-up.

Please support HHV-6 University by purchasing one or our books about the cover-up of the relationship between HHV-6 and Chronic Fatigue Syndrome, AIDS, and many other immunological illnesses. Click book to read a free excerpt.

The state of CFS research

Three Big Books

Two books on amazon

Everyone needs to know what the CDC is hiding about CFS and HHV-6. NEW YORK NATIVE contains both volumes of THE CHRONIC FATIGUE SYNDROME EPIDEMIC COVER-UP. The print version is $23. Only $7.98 in Kindle.

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