HHV-6 University

"One large COVID-19 study hints at the potential benefit of an experimental drug called remdesivir, even as another study published the same day has disappointing results. But both studies had flaws, making results difficult to interpret in the absence of more research." Source: NBC https://www.nbcnews.com/health/health-news/coronavirus-drug-remdesivir-shows-promise-large-trial-n1195171

Please be aware there are skin signs of covid. Purple red papules on the fingers and toes. Looks like chilblains/ pernio. May have no other covid symptoms. Seen in young people. Images of pernio like changes of Covid-19 from Italy @TamarPedsRheum @NataliaVasCan @IreneBlancoMD pic.twitter.com/5jKp04Yykq — Dawn Wahezi (@DWahezi) April 11, 2020 COVID-19 and African Swine ... by rubiconmedia on Scribd

https://lmtribune.com/coronavirus/um-researchers-using-grant-to-work-toward-covid-19-vaccine/article_0d55c0b2-2880-5fc8-b644-1ab2875d78f9.html COVID-19 and African Swine ... by rubiconmedia on Scribd

"Though more research is needed, a growing number of case reports and preliminary studies suggest SARS-CoV-2, the virus that causes COVID-19, can also affect the skin." https://www.msn.com/en-us/health/medical/from-covid-toes-to-hives-these-are-the-skin-conditions-dermatologists-think-could-be-signs-of-coronavirus/ar-BB13jTNC?ocid=spartanntp

Photo Source: http://www.cfsph.iastate.edu/DiseaseInfo/disease-images.php?name=african-swine-fever&lang=en COVID-19 and African Swine ... by rubiconmedia on Scribd

Rare inflammatory syndrome seen in US child with Covid-19 https://www.msn.com/en-us/health/health-news/rare-inflammatory-syndrome-seen-in-us-child-with-covid-19/ar-BB13lKks?ocid=spartanntp HHV-6 and Kawasaki Disease Abstract Eighteen of a total of 22 serum specimens (81.8%) from patients with Kawasaki disease were positive for immunoglobulin G or M antibodies to human herpesvirus 6, whereas 10 of 16 age- and sex-matched healthy controls (62.5%) were seropositive. Additionally, increased geometric mean antibody titers of immunoglobulin G were shown in these patients. These results suggest that the status of human herpesvirus 6 infection may be a reflection of the immunologic alterations that are associated with Kawasaki disease. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC267029/ COVID-19 and African Swine ... by rubiconmedia on Scribd

Source: https://www.washingtonexaminer.com/news/paid-for-the-damn-virus-thats-killing-us-giuliani-rips-fauci-over-grants-to-wuhan-laboratory

For ME/CFS patients, viral immunities come at a devastating, lifelong cost New research shows a connection between a common human herpes virus-6 exposure that leaves a DNA copy of the virus behind and many of the symptoms of a disabling disease called myalgic encephalomyelitis/chronic fatigue syndrome Mylagic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a disabling and complex illness. Affected persons often cannot pursue ordinary activities -- physical or mental -- because of an incapacitating loss of energy and other symptoms, and may find themselves confined to bed or house-bound for years. Anyone can develop ME/CFS, though it most commonly afflicts people between the ages of 40 and 60; women more often than men. In nearly every case, ME/CFS begins after a sequence of severe environmental exposures, injuries or infections. Until relatively recently, the utter mystery and complexity of ME/CFS persuaded some that it was not a...

Human Herpesvirus-6 Reactivation, Mitochondrial Fragmentation, and the Coordination of Antiviral and Metabolic Phenotypes in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Philipp Schreiner , Thomas Harrer , Carmen Scheibenbogen , Stephanie Lamer , Andreas Schlosser , Robert K. Naviaux and Bhupesh K. Prusty ImmunoHorizons April 1, 2020, 4 (4) 201-215; DOI: https://doi.org/10.4049/immunohorizons.2000006 Abstract Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a multifactorial disorder with many possible triggers. Human herpesvirus (HHV)–6 and HHV-7 are two infectious triggers for which evidence has been growing. To understand possible causative role of HHV-6 in ME/CFS, metabolic and antiviral phenotypes of U2-OS cells were studied with and without chromosomally integrated HHV-6 and with or without virus reactivation using the histone deacetylase inhibitor trichostatin-A. Proteomic analysis was conducted by pulsed stable isotope la...

Pigs all over China have a disease that causes Disseminated Intravascular Coagulation. Are they the source of Disseminated Intravascular Coagulation in COVID-19 patients? We still don't know if the COVID-19 virus in circulating in pigs in Wuhan and Hubei. If pigs are the source of COVID-19, it raises the possibility that all the catastrophic blood problems are caused by a cofactor of African Swine Fever virus. Are people getting both COVID-19 and African Swine Fever related Disseminated Intravascular Coagulation as a result of a coinfection that began in China's pigs? COVID-19 and African Swine ... by rubiconmedia on Scribd

"Since the end of last century, however, it has been emphasized that DIC equals a sign that “ Death Is Coming ”. DIC is now recognized an independent disease entity characterized by the intravascular activation of coagulation with loss of localization arising from different causes, including trauma and sepsis." https://www.biomedcentral.com/collections/DIC We still don't know if the COVID-19 virus in circulating in pigs in Wuhan and Hubei. If pigs are the source of COVID-19, it raises the possibility that all the catastrophic blood problems are caused by a cofactor of African Swine Fever virus. Are people getting both COVID-19 and African Swine Fever related Disseminated Intravascular Coagulation as a result of a coinfection that began in China's pigs? COVID-19 and African Swine ... by rubiconmedia on Scribd

Britain’s national health authority issued a worrisome alert about children, covid-19 and potential complications "Some of the children had tested positive for covid-19 while others had not." Source: Washington Post https://www.washingtonpost.com/health/2020/04/27/britains-national-health-authority-issued-worrisome-alert-about-children-covid-19-potential-complications/ COVID-19 and African Swine ... by rubiconmedia on Scribd

Source: Newsweek https://www.newsweek.com/uk-health-officials-warn-coronavirus-related-inflammatory-condition-could-emerging-children-1500369 "The Paediatric Intensive Care Society shared the alert on Twitter, which reportedly stated that the cases have "common overlapping features of toxic shock syndrome and atypical Kawasaki Disease with blood parameters consistent with severe COVID-19 in children." A life-threatening condition, toxic shock syndrome occurs when bacteria gets inside the body and lets off harmful toxins. Kawasaki Disease, meanwhile, is a condition which generally affects those under the age of five, and is characterized by a rash, swollen glands in the neck, dry cracked lips, red fingers or toes, and red eyes."

A serious coronavirus-related syndrome may be emerging in the UK, according to an “urgent alert” issued to doctors, following a rise in cases in the last two to three weeks, HSJ has learned. An alert to GPs and seen by  HSJ says that in the “last three weeks, there has been an apparent rise in the number of children of all ages presenting with a multisystem inflammatory state requiring intensive care across London and also in other regions of the UK”. It adds: “There is a growing concern that a [covid-19] related inflammatory syndrome is emerging in children in the UK, or that there may be another, as yet unidentified, infectious pathogen associated with these cases.” https://www.hsj.co.uk/acute-care/exclusive-national-alert-as-coronavirus-related-condition-may-be-emerging-in-children/7027496.article

HERV-K and HERV-W transcriptional activity in Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome Abstract Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFSMS) is an incapacitating chronic disease that dramatically compromise the life quality. The CFS/ME pathogenesis is multifactorial, and it is believed that immunological, metabolic and environmental factors play a role. It is well documented an increased activity of Human endogenous retroviruses (HERVs) from different families in autoimmune and neurological diseases, making these elements good candidates for biomarkers or even triggers for such diseases. Here the expression of Endogenous retroviruses K and W (HERVK and HERVW) was determined in blood from moderately and severely affected ME/CFS patients. HERVK was overexpressed only in moderately affected individuals and HERVW showed no difference. This is the first report about HERVK differential expression in moderate ME/CFS. https://www.biorxiv.org/content/10.1101/...

https://www.washingtontimes.com/news/2020/apr/27/anthony-fauci-should-explain-37-million-wuhan-labo/ From the Sun: Covid-19  was originally thought to have come from a so-called  “wet market” in the Chinese city. But there has been mounting speculation linking the disease to the lab, which is one of two in Wuhan, and a possible leak. Scientists at WIV experimented on bats as part of a project funded by the US National Institutes of Health , which licences it to receive American money, the Mail on Sunday reports. Research published in April 2018 probed the cross-species transmission of coronaviruses from bats, to other animals, and then to humans. The study - titled "'fatal swine acute diarrhoea syndrome caused by an HKU2-related coronavirus of bat origin" - was investigating a bat-related coronavirus outbreak on Chinese pig farms. Bats were captured in a cave and samples were taken from the creatures. Scientists then ...