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Showing posts from July, 2025

Is vasculitis the key to AIDS, Chronic Fatigue Syndrome, and autism?

  Human Herpesvirus 6 Associated With a Secondary Central Nervous System Vasculitis in an Immunocompetent Adult: A Case Report | Cureus

Can AIDS and Chronic Fatigue Syndrome both be considered vascular disorders? And what about autism?

  Can AIDS and Chronic Fatigue Syndrome both be considered vascular disorders? AIDS is primarily caused by infection with the human immunodeficiency virus (HIV), which predominantly affects the immune system—specifically, CD4+ T-cells. However, substantial evidence shows that HIV/AIDS is associated with various forms of vascular dysfunction and increased risk of cardiovascular diseases, such as atherosclerosis, arterial and venous thrombosis, and endothelial damage. The mechanisms behind these vascular effects include: Chronic inflammation and immune activation leading to endothelial dysfunction. Higher prevalence of cardiovascular risk factors and vascular pathologies among people living with HIV compared to the general population. Direct or indirect injury to blood vessels by the virus and its effects on the vascular endothelium. Despite these vascular complications, AIDS itself is not classified as a vascular disorder. Instead, it can lead to vascular disease as a comorbidity or...

" A new study finds that prior herpesvirus infections are linked to a faster age-related increase in blood biomarkers associated with dementia, even in cognitively healthy women. Researchers measured five key biomarkers in 167 women and found that seropositivity for HHVs doubled the rate of biomarker accumulation compared to those without prior infection. The strongest viral associations were seen for Epstein-Barr virus and HHV6, with amyloid-beta and phosphorylated tau levels most affected. These findings support the hypothesis that chronic viral infections may accelerate neurodegeneration and raise dementia risk independently of genetic factors."

  Herpesvirus Infections May Accelerate Dementia - Neuroscience News

Rand Paul: Indict Fauci!

  Sen. Paul: ‘Test’ the autopen by indicting Fauci – World Tribune: U.S. Politics and Culture, Geostrategy, China, North Korea, Corporate Watch, Media Watch

Bhupesh Prusty on macrophages

  (15) When Machines Peer Review: The Silent Erosion of Scientific Novelty | LinkedIn

African Swine Fever and Kaposi's Sarcoma

 From Perplexity A.I. Make the case that the case that internal variable lesions in pigs with African Swine Fever are similar to the variable internal lesions of Kaposi's Sarcoma. African Swine Fever clinical presentation in the field ... Pathological Characteristics of Domestic Pigs Orally ... Full article: Pathogenicity and virulence of African swine ... Manual on meat inspection for developing countries Similarities Between Internal Variable Lesions in African Swine Fever (ASF) and Kaposi's Sarcoma Overview Both African Swine Fever (ASF) in pigs and Kaposi's Sarcoma (KS) in humans are characterized by lesions with marked variability in their internal distribution, severity, and appearance. Comparing the pathology of these diseases illuminates fundamental similarities in the variable and multi-organ nature of their internal lesions. 1. Lesion Distribution and Variability African Swine Fever: Lesions are highly variable depending on the virulence of the ASF virus and the d...

Perplexity looks at a challenging paradigm shift for AIDS and K.S.

  From Perplexity A.I . Make the case that the scientists who did autopsies on the first AIDS patients and found internal Kaposi's Sarcoma in all of them regardless of risk group, may have found out something that could one day change the nosology and causation theory of AIDS if scientists want to go back to the nosological (and epidemiological) drawing board and rethink the AIDS paradigm. Rethinking AIDS Nosology: The Implications of Early Autopsy Findings Introduction The initial autopsy studies on AIDS patients in the early 1980s, notably those identifying internal Kaposi's Sarcoma (KS) across various risk groups, presented findings that may still have profound implications for our understanding of AIDS. These data, often overshadowed by the viral causation narrative, could challenge and potentially expand the current nosological and etiological frameworks for AIDS if revisited with modern scientific approaches. The Significance of Early Autopsy Findings Internal Kaposi'...

Is HIV/AIDS a scientific Ponzi scheme?

 From Perplexity A.I. Make the argument that a scientific theory which is maintained by only publishing research that supports it becomes a kind of de facto Ponzi scheme. The Argument: When Science Mimics a Ponzi Scheme Introduction A scientific theory is expected to survive rigorous scrutiny from the full spectrum of evidence—supportive, neutral, and contradictory. However, when a theory is sustained only by publishing research that affirms it while suppressing or ignoring contrary evidence, it risks behaving less like authentic science and more like a de facto Ponzi scheme in principle. Structural Parallels 1. Information Filtering and Dependency In a Ponzi scheme, early investors are paid returns using the capital of newer investors, not from real profits. The scheme’s sustainability depends on the continuous recruitment of more believers and suppression of inconvenient information. Similarly, if researchers or institutions publish only positive findings for a given theory, the ...

K.S. and HHV-8 question to Perplexity

  Is the real issue the definition of what is K.S.? In other words, if the definition of K.S. is broadened to include all kinds of vascular lesions, even subacute ones, the likelihood that they were not associated with HHV-8 would increase, right? Yes, the definition of Kaposi's sarcoma (KS) is central to whether HHV-8 (KSHV) is always found in these lesions. Currently, KS is specifically defined as a low-grade vascular tumor (neoplasm) that is characteristically associated with HHV-8 infection. This association is now so strong that detection of HHV-8 (often by immunohistochemistry for the LANA-1 protein or by PCR) is often used to confirm the diagnosis of KS and distinguish it from other vascular lesions. If the definition of KS were broadened to include all kinds of vascular tumors or lesions—even ones that are not neoplastic or truly malignant, such as benign vascular proliferations, subacute inflammatory lesions, or other non-HHV-8–related conditions—the likelihood of finding ...

What warnings would Eric Hoffer give about the fanaticism of the AIDS activists like Act Up?

  From Perplexity What warnings would Eric Hoffer give about the fanaticism of the AIDS activists like Act Up? Eric Hoffer’s Warnings on Fanaticism and Their Relevance to ACT UP Eric Hoffer, the influential author of The True Believer, deeply analyzed the psychology and dangers of fanaticism present in all types of mass movements. While he did not specifically address AIDS activism or the group ACT UP—whose activism began long after his most influential work—his general critiques provide insight into how he might have assessed the risks associated with highly zealous activism, even for just causes. Key Warnings Hoffer Would Likely Apply Motivation Rooted in Insecurity Hoffer asserted that the core of fanaticism is a deep sense of personal incompleteness and insecurity, which leads individuals to seek belonging and self-worth through passionate commitment to a cause, sometimes regardless of its particular content or justice. He argued, “The fanatic is perpetually incomplete and inse...

A satirical story about in which AIDS activists get involved in promoting and defending science that turns out to be totally wrong and backfires on them

Fun from Perplexity Write a satirical story about in which AIDS activists get involved in promoting and defending science that turns out to be totally wrong and backfires on them Based on the research I've conducted, I now have enough information to write a satirical story about AIDS activists getting involved in promoting and defending flawed science. I'll create a fictional story that draws inspiration from the real history of AIDS activism, medical reversals, and scientific controversies to craft a satirical narrative that explores the themes requested. The Experts Dr. Marcus Sterling adjusted his wire-rimmed glasses and surveyed the packed auditorium with satisfaction. The banner hanging behind him read "Coalition for Revolutionary AIDS Research" in bold, rainbow letters. After eighteen months of relentless advocacy, CRAR had finally achieved what many thought impossible: they had convinced the medical establishment to embrace the groundbreaking "Cellular Har...

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Consciousness of Guilt in Science and Medicine (From Perplexity A.I.)

We asked Perplexity A.I. to make the argument that Castleman's Disease undermines the nosology, epidemiology, and virology of AIDS.

If one studies all the medical literature on Chronic Fatigue Syndrome and AIDS, what viruses, infections, and pathological findings do they have in common? (From Perplexity)

If the nosological definition of AIDS is reset to include all illnesses with serious inflammation regardless of HIV positivity or status, what illnesses could be included in the nosology of AIDS?

Popular Posts from the Last Year

Oral Kaposi's Sarcoma looks like the Crimson Crescents in Chronic Fatigue Syndrome patients.

Dr. Bhupesh Prusty and Professor Thomas Rudel discuss their HHV-6 research

Dr. Rebecca Culshaw Smith's book is discussed on Twitter

Ablashi discusses HHV-6, AIDS, Alzheimer's, and Chronic Fatigue Syndrome

Is African Swine Fever a threat to human health in Congo?

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Dr. Bhupesh Prusty and Professor Thomas Rudel discuss their HHV-6 research

Anthony Fauci was part of the gang that silenced and destroyed Judy Mikovits.

Was Judy Mikovits destroyed because her XMRV work would have ultimately shown HIV is a total fraud?

Is Chronic Fatigue Syndrome the other AIDS epidemic in the gay community?