Reduction of Adverse Effects by a Mushroom Product, Active Hexose Correlated Compound (AHCC) in Patients With Advanced Cancer During Chemotherapy-The Significance of the Levels of HHV-6 DNA in Saliva as a Surrogate Biomarker During Chemotherapy.

http://www.ncbi.nlm.nih.gov/pubmed/24611562

Abstract

Chemotherapy improves the outcome of cancer treatment, but patients are sometimes forced to discontinue chemotherapy or drop out of a clinical trial due to adverse effects, such as gastrointestinal disturbances and suppression of bone marrow function. The objective of this study was to evaluate the safety and effectiveness of a mushroom product, active hexose correlated compound (AHCC), on chemotherapy-induced adverse effects and quality of life (QOL) in patients with cancer. Twenty-four patients with cancer received their first cycle of chemotherapy without AHCC and then received their second cycle with AHCC. During chemotherapy, we weekly evaluated adverse effects and QOL via a blood test, EORTC QLQ-C30 questionnaire, and DNA levels of herpes virus type 6 (HHV-6) in saliva. The DNA levels of HHV-6 were significantly increased after chemotherapy. Interestingly, administration of AHCC significantly decreased the levels of HHV-6 in saliva during chemotherapy and improved not only QOL scores in the EORTC QLQ-C30 questionnaire but also hematotoxicity and hepatotoxicity. These findings suggest that salivary HHV-6 levels may be a good biomarker of QOL in patients during chemotherapy, and that AHCC may have a beneficial effect on chemotherapy-associated adverse effects and QOL in patients with cancer undergoing chemotherapy.

Popular Posts in the Last 7 Days

A Perplexity conversation about self-deceit, conspiracy, Arendt and AIDS

Perplexity on Rebecca Culshaw Smith, and PrEP as Genocide

A moment of truth every intellectual and scientist in France, Europe and Russia should be aware of!

All these mistakes have been made in AIDS and they have led to the Chronic Fatigue Syndrome epidemic

HHV-6: The 50 Shades of AIDS Virus

Why Brigitte Huber may be the most important AIDS and Chronic Fatigue Syndrome researcher

From Perplexity A.I.: List 20 questions that would make the HIV establishment (which has demonized critics of the HIV theory) uncomfortable.

Popular Post in the Last 30 Days

Memo to CFS patients and CFS quacks: Let's get something straight.

A Perplexity conversation about self-deceit, conspiracy, Arendt and AIDS

Is Chronic Fatigue Syndrome Associated Kaposi's Sarcoma (CFSKS) a diagnosis all doctors should become aware of?

Perplexity on Rebecca Culshaw Smith, and PrEP as Genocide

Today Only!

Why Brigitte Huber may be the most important AIDS and Chronic Fatigue Syndrome researcher

From Perplexity A.I.: List 20 questions that would make the HIV establishment (which has demonized critics of the HIV theory) uncomfortable.

Groq on Hannah Arendt and science

Popular Posts from the Last Year

Perplexity on Rebecca Culshaw Smith, and PrEP as Genocide

Why Brigitte Huber may be the most important AIDS and Chronic Fatigue Syndrome researcher

From Perplexity A.I.: A major nosological mistake in AIDS—meaning a fundamental error in how the disease is defined, classified, or diagnosed—could be the most consequential nosological error in history because of several deeply impactful social, scientific, and ethical consequences.

Oral Kaposi's Sarcoma looks like the Crimson Crescents in Chronic Fatigue Syndrome patients.

How Kaposi's Sarcoma almost undermined the HIV theory of AIDS

If the establishment decides that the nosology of AIDS is wrong and HIV is not the cause of AIDS could that be considered a Black Swan event?

Perplexity on the issue of endogenous versus exogenous retroviruses. Is this a key to the HIV mistake?

A Perplexity conversation about self-deceit, conspiracy, Arendt and AIDS

All Time Most Popular Posts

Dr. Bhupesh Prusty and Professor Thomas Rudel discuss their HHV-6 research

Anthony Fauci was part of the gang that silenced and destroyed Judy Mikovits.

Was Judy Mikovits destroyed because her XMRV work would have ultimately shown HIV is a total fraud?

Is Chronic Fatigue Syndrome the other AIDS epidemic in the gay community?