Clinical features associated with Macrophagic Myofasciitis

 http://journal.frontiersin.org/Journal/111872/abstract

Macrophagic myofasciitis (MMF) is an emerging condition characterized by specific muscle lesions assessing abnormal long-term persistence of aluminium hydroxide within macrophages at the site of previous immunization. Affected patients usually are middle-aged adults, mainly presenting with diffuse arthromyalgias, chronic fatigue, and marked cognitive deficits, not related to pain, fatigue or depression. Clinical features usually correspond to that observed in chronic fatigue syndrome/myalgic encephalomyelitis. Representative features of MMF-associated cognitive dysfunction include dysexecutive syndrome, visual memory impairment and left ear extinction at dichotic listening test. Most patients fulfil criteria for non-amnestic/dysexecutive mild cognitive impairment, even if some cognitive deficits appear unusually severe. Cognitive dysfunction seems stable over time despite marked fluctuations. Evoked potentials may show abnormalities in keeping with central nervous system involvement, with a neurophysiological pattern suggestive of demyelination. Brain perfusion SPECT shows a pattern of diffuse cortical and subcortical abnormalities, with hypoperfusions correlating with cognitive deficiencies. The combination of musculoskeletal pain, chronic fatigue and cognitive disturbance generates chronic disability with possible social exclusion. Classical therapeutic approaches are usually unsatisfactory making patient care difficult.

Popular Posts in the Last 7 Days

Anthony Fauci was part of the gang that silenced and destroyed Judy Mikovits.

Why HIV should be referred to as "a red herring."

The case that HHV-6 maybe the biggest unrecognized public health threat in the world.

Dr. Rebecca Culshaw Smith's book is discussed on Twitter

Doctors discuss using Chloroquine for COVID-19

Inconsistencies in the HIV theory of AIDS

Ablashi discusses HHV-6, AIDS, Alzheimer's, and Chronic Fatigue Syndrome

Popular Post in the Last 30 Days

Why HIV should be referred to as "a red herring."

The case that HHV-6 maybe the biggest unrecognized public health threat in the world.

Inconsistencies in the HIV theory of AIDS

Anthony Fauci was part of the gang that silenced and destroyed Judy Mikovits.

Dr. Rebecca Culshaw Smith's book is discussed on Twitter

Oral Kaposi's Sarcoma looks like the Crimson Crescents in Chronic Fatigue Syndrome patients.

Popular Posts from the Last Year

Oral Kaposi's Sarcoma looks like the Crimson Crescents in Chronic Fatigue Syndrome patients.

Dr. Rebecca Culshaw Smith's book is discussed on Twitter

Ablashi discusses HHV-6, AIDS, Alzheimer's, and Chronic Fatigue Syndrome

Doctors discuss using Chloroquine for COVID-19

Dr. Bhupesh Prusty and Professor Thomas Rudel discuss their HHV-6 research

Why HIV should be referred to as "a red herring."

All Time Most Popular Posts

Dr. Bhupesh Prusty and Professor Thomas Rudel discuss their HHV-6 research

Anthony Fauci was part of the gang that silenced and destroyed Judy Mikovits.

Was Judy Mikovits destroyed because her XMRV work would have ultimately shown HIV is a total fraud?

Is Chronic Fatigue Syndrome the other AIDS epidemic in the gay community?