Does the dose influence in African Swine Fever have something to teach us about HHV-6 dose influence in AIDS and Chronic Fatigue Syndrome?

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 Influence of Age and Dose of African Swine Fever Virus Infections on Clinical Outcome and Blood Parameters in Pigs | Viral Immunology (liebertpub.com)


Abstract

African swine fever (ASF) is a fatal disease for domestic pigs, leading to serious economic losses in countries where ASF is endemic. Despite extensive research, efficient vaccines against ASF are lacking. Since peripheral blood cells are important mediators for vaccines, we study the impact of ASF on blood parameters in pigs with different ages and infected with different doses of ASF virus. Four different groups were studied: (1) 12 weeks of age/low virus dose; (2) 12 weeks of age/high virus dose; (3) 18 weeks of age/low virus dose; and (4) 18 weeks of age/high virus dose. By varying in age and/or ASFV inoculation dose, we monitor blood parameters during different degrees of disease. Thirty percent of the pigs survived the infection with a moderately virulent strain of African swine fever virus (ASFV). Animals that did survive infection were generally older, independent from the inoculation dose used. A firm reduction in many different cell types at 3–5 days postinfection (DPI) was accompanied by an increase in body temperature, followed by clinical signs and mortality from day 6 PI. While blood parameters generally normalized in survivors, γδ T cells and IL-10 levels could be related to mortality. These conclusions should be considered in new approaches for protection against ASF.

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Perplexity on Kaposi's Sarcoma

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  Here are 20 unexpected findings about Kaposi's Sarcoma (KS), based on recent research and case reports: Unusual Locations and Presentations KS can occur in extremely rare sites such as the thyroid gland, musculoskeletal system, central and peripheral nervous system, larynx, eye, and major salivary glands. pmc.ncbi.nlm.nih ​ Some patients present with KS lesions in the stomach, small intestine, liver, spleen, mesentery, and lungs, with no visible skin involvement. sciencedirect +1 ​ There have been cases where KS was discovered at autopsy despite no prior clinical suspicion, indicating hidden disseminated disease. keio.elsevierpure +1 ​ KS can manifest as pleural and pericardial effusions, ascites, and hyperechoic liver and spleen lesions, which can be detected by bedside ultrasound. emra ​ New Subtypes and Populations A new subtype of KS has been described among men who have sex with men (MSM) without HIV infection. eatg ​ KS can occur in individuals recently diagnosed with HIV, ...
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Help end Fauci's Tuskegee Syphilis Experiment!

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Please send an email to Dr. Francis Collins, the Director of the National Institutes of Health. Francis.Collins@nih.hhs.gov Francis S. Collins Director of the National Institutes of Health  9000 Rockville Pike Bethesda, Maryland 20892 Dear Dr. Collins: It's time that the public knew about all the diseases HHV-6 is causing in our society. The days of using the fraudulent HIV paradigm of AIDS to cover up the HHV-6 pandemic must come to an end! You shouldn't try to control panic about HHV-6 by lying to the public. I urge you to support the goals of International HHV-6 Protests and Teach-ins that will be taking place at universities all over the world during the next several years. Those goals include the support of freedom of thought, speech and dissent in science in general and in research of HHV-6-related diseases in particular. HHV-6-releated diseases include so-called "AIDS" and "Chronic Fatigue Syndrome...
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Perplexity on Rebecca Culshaw Smith, and PrEP as Genocide

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  Rebecca Culshaw’s Substack articles establish a foundation for arguing that the mass promotion and use of PrEP (pre-exposure prophylaxis) in HIV prevention could be considered a form of “genocide,” rooted in several lines of critique that challenge both the scientific and ethical underpinnings of the intervention. ​ Critique of Efficacy Claims Culshaw repeatedly questions the reliability of the efficacy data cited for PrEP, especially the widely publicized claim of “99% effectiveness.” She critiques the primary studies behind this figure, particularly the UK “Impact Trial,” highlighting that its actual observed efficacy was only 86%, and that even this figure is derived from retrospective, less scientifically rigorous analysis. She emphasizes that PrEP, to justify the aggressive and potentially coercive marketing campaigns behind it, should meet a much higher bar of evidence given its target population often consists of healthy individuals. By questioning what she perceives as st...
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K.S. and the Jane Teas ASFV hypothesis of AIDS

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  Are spindle cells found in ASFV lesions in pigs? Spindle-shaped cells have been reported in ASFV (African Swine Fever Virus) lesions in pigs, particularly in areas with hemorrhagic lesions such as the epicardium and renal pelvis. These spindle-shaped cells were observed to be labeled with ASFV antigen, indicating that they are infected or affected by the virus. However, the primary cell types infected by ASFV in pigs are macrophages and monocytes, which are more consistently reported as the main targets in the spleen and other organs. While spindle-shaped cells can be found in certain ASFV lesions, they are not considered the main cell type involved in ASFV infection, but rather a morphological feature observed in specific pathological contexts. pmc.ncbi.nlm.nih +2 ​ https://pmc.ncbi.nlm.nih.gov/articles/PMC10927503/ https://journals.asm.org/doi/10.1128/spectrum.02902-24 https://www.frontiersin.org/journals/veterinary-science/articles/10.3389/fvets.2022.978398/full https://www.na...
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Human herpesvirus 6 (HHV-6) infection and risk of Alzheimer’s disease: a systematic review and meta-analysis

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  This meta-analysis suggests that HHV-6 infection is significantly associated with an increased risk of Alzheimer’s disease. Nevertheless, the exact causal mechanisms remain unclear. Further longitudinal and mechanistic studies are needed to better understand the role of HHV-6 in Alzheimer’s pathogenesis and to evaluate potential antiviral options for preventive or therapeutic strategies. Human herpesvirus 6 (HHV-6) infection and risk of Alzheimer’s disease: a systematic review and meta-analysis | BMC Neurology | Full Text
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Dr. Konstance Knox explains why HHV-6 may be the key to dealing with AIDS.

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  by Neenyah Ostrom New York Native , issue #678, April 15, 1996 Konstance Knox, Ph.D., is an HHV-6 researcher who has just published a study with extraordinary implications for AIDS research and treatment strategies. Along with colleague Donald R. Carrigan, Ph.D., Knox demonstrated that 100 percent of HIV-infected patients studied (ten out of ten) had active Human Herpes Virus 6 Variant A infections in their lymph nodes early in the course of their disease. Seventy-five percent of these patients, in fact, had CD4 cell counts higher than 200 (the cut-off for receiving a diagnosis of AIDS), up to as high a CD4 count as 700. This finding led Knox and Carrigan to conclude that "active HHV-6 infections appear relatively early in the course of HIV disease and in vitro studies suggest that the A variant of HHV-6 is capable of breaking HIV latency, with the potential for helping to catalyze the progression of HIV infection to AIDS." This new study, in other words, presents data furt...
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Perplexity on Rebecca Culshaw Smith, and PrEP as Genocide

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  Rebecca Culshaw’s Substack articles establish a foundation for arguing that the mass promotion and use of PrEP (pre-exposure prophylaxis) in HIV prevention could be considered a form of “genocide,” rooted in several lines of critique that challenge both the scientific and ethical underpinnings of the intervention. ​ Critique of Efficacy Claims Culshaw repeatedly questions the reliability of the efficacy data cited for PrEP, especially the widely publicized claim of “99% effectiveness.” She critiques the primary studies behind this figure, particularly the UK “Impact Trial,” highlighting that its actual observed efficacy was only 86%, and that even this figure is derived from retrospective, less scientifically rigorous analysis. She emphasizes that PrEP, to justify the aggressive and potentially coercive marketing campaigns behind it, should meet a much higher bar of evidence given its target population often consists of healthy individuals. By questioning what she perceives as st...
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If one assumeS Rebecca Culshaw's Substack is correct, what were 20 moments in the last 40 ears when scientist should have recognized something was wrong in the HIV/AIDS paradigm?

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From Perplexity A.I.   Assuming Rebecca Culshaw's Substack and books are correct, here are 20 moments in the last 40 years when scientists should have recognized fundamental problems in the HIV/AIDS paradigm, based on major controversies, failed predictions, and repeatedly anomalous findings highlighted by critics like Culshaw and others: Key Moments Highlighting Paradigm Failures 1984: Early claims of HIV as the sole cause of AIDS were made before conclusive evidence, leading to widespread adoption of a viral paradigm without rigorous challenge or alternate hypothesis consideration. ​ Mid-1980s: Discovery disputes between Luc Montagnier (France) and Robert Gallo (US) over the "AIDS virus" involved accusations of sample misappropriation and scientific misconduct, but were glossed over for the sake of an international consensus. ​ 1987: Peter Duesberg publicly challenged the HIV-AIDS causation model, noting unanswered questions around risk group disease patterns and viral ...
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  Activation of endogenous retrovirus reverse transcriptase in multiple sclerosis patient lymphocytes by inactivated HSV-1, HHV-6 and VZV - Aarhus University Abstract Human endogenous retroviruses (HERVs) and herpesviruses have been associated with the development of multiple sclerosis (MS). These virus groups interact with each other and have been shown to induce synergistic immune responses. Here, we focus on the possible role of herpesviruses as contributing factors in HERV activation. We demonstrate the ability of HSV-1, HHV-6, and VZV antigens to induce higher RT activity in peripheral lymphocytes from MS patients vs. controls during the first 6 days post-antigen stimulation. On subsequent days, only VZV can sustain the increase in the RT expression in cells from MS patients. The RT induction does not depend on herpes replication.
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Perplexity on Kaposi's Sarcoma

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  Here are 20 unexpected findings about Kaposi's Sarcoma (KS), based on recent research and case reports: Unusual Locations and Presentations KS can occur in extremely rare sites such as the thyroid gland, musculoskeletal system, central and peripheral nervous system, larynx, eye, and major salivary glands. pmc.ncbi.nlm.nih ​ Some patients present with KS lesions in the stomach, small intestine, liver, spleen, mesentery, and lungs, with no visible skin involvement. sciencedirect +1 ​ There have been cases where KS was discovered at autopsy despite no prior clinical suspicion, indicating hidden disseminated disease. keio.elsevierpure +1 ​ KS can manifest as pleural and pericardial effusions, ascites, and hyperechoic liver and spleen lesions, which can be detected by bedside ultrasound. emra ​ New Subtypes and Populations A new subtype of KS has been described among men who have sex with men (MSM) without HIV infection. eatg ​ KS can occur in individuals recently diagnosed with HIV, ...
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Perplexity A.I. discusses K.S.

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  Make the case that separating HIV and the KS virus epidemic into two parallel or intertwined epidemics actually undermines the whole AIDS paradigm. Separating the HIV and Kaposi's Sarcoma (KS) virus epidemics into two parallel or even just intertwined epidemics actually threatens the conceptual foundation of the AIDS paradigm. The classic AIDS model posits a single, unifying cause—HIV—that triggers a collapse in immune function and thereby “allows” a diverse range of rare infections and cancers, including KS, to emerge. If, instead, KS is attributable to a distinct viral agent (KSHV/HHV-8) acting in parallel with HIV, the paradigm shifts from a single-cause immunodeficiency syndrome to a more complex multi-agent, ecological interplay. AIDS Paradigm: Unified Causation The original AIDS paradigm was built on the conviction that HIV-induced immunosuppression is both necessary and sufficient to account for the spectrum of AIDS-defining illnesses, including opportunistic infections an...
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Ablashi discusses HHV-6, AIDS, Alzheimer's, and Chronic Fatigue Syndrome

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"HHV-6 is actually likely to reduce HIV patient survival by accelerating the depletion of CD4 and CD8 T cells. HHV-6A was shown to accelerate AIDS progression in macaques.  Macaques co-infected with simian HIV and HHV-6A died quickly and showed a dramatic depletion in both CD4+ and CD8+ T cells, whereas those infected with only simian HIV never progressed to full blown AIDS."  "We believe that infections are the most logical explanation for the inflammation neurodegeneration associated with Alzheimer’s , but don’t believe that there is a single pathogen responsible. HHV-6A and HHV-7 were identified as likely culprits in 2018 paper , using RNAseq analysis by Readhead and team. Two subsequent studies did not find an increase in HHV-6/7 using the same data, but at the same time did not find a significant presence of ANY herpesviruses in the brain, which we know is not the case. Dozens of careful studies have identified a high prevalence of low-level HHV-6 and HSV1 DN...
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Transplant Complications Bone marrow supression Colitis/diarrhea Delirium/CNS Dysfunction Encephalitis/Amnesia GVHD Hemophagocytic syndrome Hepatitis /Liver failure Pneumonitis Transplant Reactivation Overview Encephalitis Encephalitis / Meningitis Overview Encephalitis in the Immunocompromised Encephalitis in the Immunocompetent Rhomboencephalitis Limbic Encephalitis Encephalomyelitis Amnesia Rash & Roseola Seizures Febrile Seizures Status Epilepticus Cognitive Dysfunction Delirium Amnesia Hypersensitivity (DIHS/DRESS) Drug Induced Hypersensitivity Syndrome (DIHS) Drug Reaction with Eosinophilia & Systemic Symptoms (DRESS) Stevens-Johnson Syndrome (SJS) Immune Suppression Bone Marrow Suppression Lymphadenopathy/Fever Possible Disease Associations Multiple Sclerosis Chronic Fatigue Syndrome Epilepsy Mesial/Temporal Lobe Epilepsy Status Epilepticus Colitis/Diarrhea Endocrine D...
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Oral Kaposi's Sarcoma looks like the Crimson Crescents in Chronic Fatigue Syndrome patients.

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This is what oral Kaposi's Sarcoma looks like. Source:  https://doctorspiller.com/kaposis-sarcoma/ Compare it to these crimson crescent lesions in the mouths of Chronic Fatigue Syndrome patients. "Burke A. Cunha, MD, discovered what he called crimson crescents in the mouths of 80% of his CFS patients. After the word got out, Cunha received calls from other parts of the country. Physicians began telling him that they also were finding the crimson crescents in their patients once they looked for them." https://www.prohealth.com/library/crimson-crescents-facilitate-chronic-fatigue-syndrome-cfs-diagnosis-11266 Chronic Fatigue Syndrome patients may have undiagnosed internal Kaposi's Sarcoma. Susan Levin found HHV-8, the Kaposi's Sarcoma virus, in half of CFS patients she looked at. Prevalence in the Cerebrospinal Fluid of the Following Infectious Agents in a Cohort of 12 CFS Subjects Susan Levine Published online: 04 Dec 2011 ABSTR...
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https://hhv-6foundation.org/cihhv-6/the-activation-of-cihhv-6-by-telomeric-circle-formation-qa-with-dr-bhupesh-prusty Tweet If you have Amazon Prime or Kindle Unlimited, you can immediately begin reading The Chronic Fatigue Syndrome Epidemic Cover-up and you will soon understand why the facts about the Chronic Fatigue Syndrome epidemic have been hidden from the public for almost four decades. Click here to begin reading Or purchase a print copy for only $20 shipped by Amazon Prime  If you want to know the truth about the Chronic Fatigue Syndrome epidemic, you need to discover the reporting of Neenyah Ostrom. For a decade, starting in 1988, Ostrom reported on Chronic Fatigue Syndrome for a newspaper called New York Native . What her reporting uncovered about the true nature of the Chronic Fatigue Syndrome epidemic will shock you.                                 ...
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Why HIV should be referred to as "a red herring."

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 From Perplexity A.I. Make the case that the critics of the HIV theory of AIDS would be more effective at their messaging to politicians and the public by constantly referring to HIV as a red herring. Critics of the HIV theory of AIDS—those who argue that HIV is not the causative agent of AIDS—often struggle to convey their message effectively to politicians and the public because the scientific consensus firmly upholds the link between HIV and AIDS. However, from a communications strategy perspective, such critics might amplify the clarity and urgency of their argument by consistently describing HIV as a "red herring." Here’s why this tactic could make their messaging more effective: 1. Framing the Narrative Labeling HIV as a "red herring" frames the dominant scientific focus on the virus as a distraction from finding the true cause of AIDS (as the critics would argue). This concise phrase presents the debate in terms of misdirection, which is an accessible and com...
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Anthony Fauci was part of the gang that silenced and destroyed Judy Mikovits.

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Read the interview in which Judy Mikovits called Chronic Fatigue Syndrome "Non-HIV AIDS." https://www.prohealth.com/library/plague-an-interview-with-judy-mikovits-32911   If you have Amazon Prime or Kindle Unlimited you can immediately begin reading this book. If you have Amazon Prime or Kindle Unlimited, you can immediately begin reading The Chronic Fatigue Syndrome Epidemic Cover-up and you will soon understand why the facts about the Chronic Fatigue Syndrome epidemic have been hidden from the public for almost four decades. Click here to begin reading Or purchase a print copy for only $20 shipped by Amazon Prime  This is the book causing heated debates about Chronic Fatigue Syndrome and HHV-6, "The Fifty Shades of AIDS Virus," in laboratories, doctor's offices, and homes all over the world.                                         ...
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Dr. Rebecca Culshaw Smith's book is discussed on Twitter

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  #AIDS #HIV #Truvada #TruvadaVictims #ClassAction An eye-opening, heart-breaking investigation. Dr. Rebecca Culshaw Smith's groundbreaking book exposes the tragic reality of 26,000 plaintiffs suing Gilead over the toxic side effects of HIV drug Truvada. https://t.co/PHVoKrafcU pic.twitter.com/hbh3mN4tdI — MyBookLists (@mybooklists) September 12, 2024
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Dr. Bhupesh Prusty and Professor Thomas Rudel discuss their HHV-6 research

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Image
https://hhv-6foundation.org/cihhv-6/the-activation-of-cihhv-6-by-telomeric-circle-formation-qa-with-dr-bhupesh-prusty Tweet If you have Amazon Prime or Kindle Unlimited, you can immediately begin reading The Chronic Fatigue Syndrome Epidemic Cover-up and you will soon understand why the facts about the Chronic Fatigue Syndrome epidemic have been hidden from the public for almost four decades. Click here to begin reading Or purchase a print copy for only $20 shipped by Amazon Prime  If you want to know the truth about the Chronic Fatigue Syndrome epidemic, you need to discover the reporting of Neenyah Ostrom. For a decade, starting in 1988, Ostrom reported on Chronic Fatigue Syndrome for a newspaper called New York Native . What her reporting uncovered about the true nature of the Chronic Fatigue Syndrome epidemic will shock you.                                 ...
Read more

Anthony Fauci was part of the gang that silenced and destroyed Judy Mikovits.

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Image
Read the interview in which Judy Mikovits called Chronic Fatigue Syndrome "Non-HIV AIDS." https://www.prohealth.com/library/plague-an-interview-with-judy-mikovits-32911   If you have Amazon Prime or Kindle Unlimited you can immediately begin reading this book. If you have Amazon Prime or Kindle Unlimited, you can immediately begin reading The Chronic Fatigue Syndrome Epidemic Cover-up and you will soon understand why the facts about the Chronic Fatigue Syndrome epidemic have been hidden from the public for almost four decades. Click here to begin reading Or purchase a print copy for only $20 shipped by Amazon Prime  This is the book causing heated debates about Chronic Fatigue Syndrome and HHV-6, "The Fifty Shades of AIDS Virus," in laboratories, doctor's offices, and homes all over the world.                                         ...
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Was Judy Mikovits destroyed because her XMRV work would have ultimately shown HIV is a total fraud?

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How much HIV research can be replicated? Is the whole field of AIDS build on HIV pseudoscience that cannot be replicated? We need an HIV replication movement that demands it all be replicated. We need to know if HIV is a solid as XMRV. How has HIV helped hide the epidemic of Chronic Fatigue Syndrome which has been called "Non-HIV AIDS"? Read this book if you want to know the whole story. Available now on Amazon here .
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Is Chronic Fatigue Syndrome the other AIDS epidemic in the gay community?

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https://www.gscene.com/news/new-doctors-guidelines-for-severe-me/ On April 16, 1996, Congressman Jerrold Nadler spoke on the floor of Congress about his request for a General Accounting investigation into how the CDC had handled the Chronic Fatigue Syndrome epidemic. Nadler did that at the urging of Charles Ortleb, the publisher and the New York Native and his reporter Neenyah Ostrom. Ortleb and Ostrom had made the case to Nadler that Chronic Fatigue Syndrome and the virus it had been linked to, HHV-6, were serious public health issues.                                                 In an interview in New York Native with Neenyah Ostrom,Congressman Nadler said, "Congress can mandate research into CFS as a viral disease. Maybe it will turn out that HHV-6A is the cause of CFS; maybe it will turn out that other viruses are involved. But Con...
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