Do pigs with African Swine Fever develop hypovolemia? Do pigs with African Swine Fever develop hypovolemia? Pigs infected with African Swine Fever (ASF) commonly develop clinical signs and pathological changes highly suggestive of hypovolemia , particularly due to the disease’s severe hemorrhagic and vascular effects. ASF causes widespread hemorrhages and vascular damage . Typical findings include petechial (pinpoint) hemorrhages in the kidneys, severe hemorrhagic lymphadenitis, pulmonary and gall bladder edema, and effusions (straw-colored or blood-stained fluid) in the pleural, pericardial, and peritoneal cavities . These extensive hemorrhages and vascular leakages can lead to a significant loss of blood volume , resulting in classic features of hypovolemic shock—such as weakness, recumbency, prostration, incoordination, pale mucous membranes, and death from shock . The underlying mechanism is severe disruption of blood vessels and disseminat...