Is this the most important fact about HHV-6's origins?

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707524/

Antibody Cross-Reactivity between Porcine Cytomegalovirus (PCMV) and Human Herpesvirus-6 (HHV-6)


Porcine cytomegalovirus (PCMV) infection is widely prevalent among pigs, and PCMV is one of the viruses which may be transmitted during xenotransplantation using pig cells, tissues, or organs. While human cytomegalovirus (HCMV) is a major risk factor for allotransplantation, it is still unclear whether PCMV is able to infect human cells or pose a risk for xenotransplantation. Previously, it was shown that transmission of PCMV after pig kidney to non-human primate transplantations resulted in a significantly reduced survival time of the transplanted organ. To detect PCMV, PCR-based and immunological methods were used. Screening of pigs by Western blot analyses using recombinant viral proteins revealed up to 100% of the tested animals to be infected. When the same method was applied to screen human sera for PCMV-reactive antibodies, positive Western blot results were obtained in butchers and workers in the meat industry as well as in normal blood donors. To exclude an infection of humans with PCMV, the sera were further investigated. PCMV is closely related to human herpesvirus-6 (HHV-6) and human herpesvirus-7 (HHV-7), and a sequence alignment of glycoprotein B suggests that the antibodies may cross-react with identical epitope sequences. HCMV is not related with PCMV, and no correlation between antibody reactivity against PCMV and HCMV was detected. These data indicate that antibodies against PCMV found in humans are cross-reactive antibodies against HHV-6.

Comparative Analysis of Roseoloviruses in Humans, Pigs, Mice, and Other Species



Popular Posts in the Last 7 Days

From Perplexity A.I.: A major nosological mistake in AIDS—meaning a fundamental error in how the disease is defined, classified, or diagnosed—could be the most consequential nosological error in history because of several deeply impactful social, scientific, and ethical consequences.

From Perplexity: HIV viral load as biomedical optical illusion.

Rebecca Culshaw in a time machine (from Perplexity)

Why no VIP doctor or scientist wants to be the first to admit that Rebecca Culshaw Smith is right about HIV/AIDS.

Rethinking AIDS Nosology in Light of Inflammation (from Perplexity)

Perplexity on Rebecca Culshaw and Chronic Fatigue Syndrome

Perplexity on Rebecca Culshaw's critics.

Popular Post in the Last 30 Days

Ablashi discusses HHV-6, AIDS, Alzheimer's, and Chronic Fatigue Syndrome

Oral Kaposi's Sarcoma looks like the Crimson Crescents in Chronic Fatigue Syndrome patients.

Dr. Bhupesh Prusty and Professor Thomas Rudel discuss their HHV-6 research

Was Judy Mikovits destroyed because her XMRV work would have ultimately shown HIV is a total fraud?

Popular Posts from the Last Year

Ablashi discusses HHV-6, AIDS, Alzheimer's, and Chronic Fatigue Syndrome

Oral Kaposi's Sarcoma looks like the Crimson Crescents in Chronic Fatigue Syndrome patients.

Why HIV should be referred to as "a red herring."

Dr. Rebecca Culshaw Smith's book is discussed on Twitter

All Time Most Popular Posts

Dr. Bhupesh Prusty and Professor Thomas Rudel discuss their HHV-6 research

Anthony Fauci was part of the gang that silenced and destroyed Judy Mikovits.

Was Judy Mikovits destroyed because her XMRV work would have ultimately shown HIV is a total fraud?

Is Chronic Fatigue Syndrome the other AIDS epidemic in the gay community?