Klimas made it obvious in 1990

 1990 "The results suggest that (ME)CFS is a form of acquired immunodeficiency"

(Nancy Klimas, Professor of Medicine, University of Miami School of Medicine: Director of Immunology; Director of AIDS research and Director of the Allergy Clinic at Miami: Immunologic Abnormalities in Chronic Fatigue Syndrome. Journal of Clinical Microbiology, June 1990:1403-1410) 



1991 The NK (natural killer) cell is a very critical cell in (ME)CFS because it is clearly negatively impacted. The most compelling finding was that the NK cell cytotoxicity in (ME)CFS was as low as we have ever seen it in any disease. This is very, very significant data. (In (ME)CFS) the actual function was very, very low --- 9% cytotoxicity: the mean for the controls was 25, In early HIV and even well into ARC (AIDS related complex, which often precedes the fully developed condition), NK cytotoxicity might be around 13 or 14 percent. (ME)CFS patients represent the lowest cytotoxicity of all populations we ve studied (Nancy Klimas, Professor of Medicine, University of Miami School of Medicine; Director of Immunology; Director of AIDS research and Director of the Allergy Clinic at Miami. Presentation: Immunological Markers in (ME(CFS. The CFIDS Association Research Conference, November 1990, Charlotte, North Carolina. Reported in CFIDS Chronicle, Spring 1991; pp 47-50)



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