Modulatory effects on dendritic cells by human herpesvirus 6 and African Swine Fever Virus
http://journal.frontiersin.org/article/10.3389/fmicb.2015.00388/abstract "Human herpesvirus 6A and 6B are β-herpesviruses approaching 100% seroprevalance worldwide. These viruses are involved in several clinical syndromes and have important immunomodulatory effects. Dendritic cells (DC) are key players in innate and adaptive immunity. Accordingly, DC are implicated in the pathogenesis of many human diseases, including infections. In this review the effects of HHV-6 infection on DC will be discussed." Wikipedia on Dendritic Cells: Dendritic cells (DCs) are antigen-presenting cells (also known as accessory cells ) of the mammalian immune system . Their main function is to process antigen material and present it on the cell surface to the T cells of the immune system. They act as messengers between the innate and the adaptive immune systems . Dendritic cells are present in those tissues that are in contact with the external environment, such as the skin (wh...